New Stent-Like device aims to seal brain aneurysms without surgery

NCT ID NCT05409989

Ongoing Disease control Sponsor: Microvention-Terumo, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing a device called FRED X, a small mesh tube placed inside an artery to block blood flow to a brain aneurysm. The goal is to see if it works as well as the earlier FRED device in preventing strokes and sealing the aneurysm. About 154 participants with a single aneurysm in the internal carotid artery are being followed for 12 months. The study is already done enrolling and is now in the follow-up phase.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

FRED X device (a stent-like implant placed in the artery to block blood flow to the aneurysm)

What this could lead to

If successful, this study could confirm that the FRED X device is a safe and effective option for treating brain aneurysms, offering a less invasive alternative to open surgery.

What could go wrong

This is a post-approval study, not a new breakthrough. The device is already approved, so the main risk is that it may not perform as well as the earlier version. Complications like stroke or incomplete aneurysm closure are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

brain aneurysm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INTRACRANIAL ANEURYSM

Contacts and locations

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Locations

Albany Medical Center

Albany, New York, 12208, United States
Baptist Healthcare System

Louisville, Kentucky, 40207, United States
Houston Methodist Hospital

Houston, Texas, 77030, United States
Massachusetts General Brigham Incorporated

Boston, Massachusetts, 02114, United States
Memorial Healthcare Systems

Hollywood, Florida, 33021, United States
Montefiore Medical Center

The Bronx, New York, 10467, United States
Mount Sinai

New York, New York, 10029, United States
Northwell Health

Manhasset, New York, 11030, United States
Norton Healthcare

Louisville, Kentucky, 40241, United States
Ochsner Health

New Orleans, Louisiana, 70121, United States
Ohio State University

Columbus, Ohio, 43210, United States
Orlando Health

Orlando, Florida, 32806, United States
ProMedica Toledo Hospital

Toledo, Ohio, 43606, United States
Queen's Medical Center

Honolulu, Hawaii, 96813, United States
Stony Brook University

Stony Brook, New York, 11794, United States
The Johns Hopkins University

Baltimore, Maryland, 21287, United States
Thomas Jefferson University

Philadelphia, Pennsylvania, 19107, United States
UMass Memorial Health

Worcester, Massachusetts, 01655, United States
University at Buffalo

Buffalo, New York, 14203, United States
University of Iowa

Iowa City, Iowa, 52242, United States
University of Kansas

Kansas City, Kansas, 66160, United States
University of Oklahoma Health Sciences Center

Oklahoma City, Oklahoma, 73104, United States
University of Pennsylvania

Philadelphia, Pennsylvania, 19104, United States