New device aims to seal brain aneurysms without surgery

NCT ID NCT04380350

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a device called Trenza for treating brain aneurysms. It involved 150 people aged 18 to 80 with a single saccular aneurysm between 6 and 12 mm. The goal was to see if the device could safely block the aneurysm from blood flow and prevent strokes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Trenza embolization device

What this could lead to

If it works, this device could offer a safe and effective way to treat brain aneurysms without open surgery.

What could go wrong

This is a post-market study, so the device is already approved. However, risks include stroke or incomplete aneurysm sealing.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Aneurysm brain aneurysm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • APHP Bicêtre

    Paris, France

  • Asklepios Hospital Hamburg St. Georg

    Hamburg, Germany

  • Besta hopsital

    Milan, Italy

  • Bordeaux Hopsital

    Bordeaux, France

  • Brest Hospital

    Brest, France

  • HCL Lyon

    Lyon, France

  • Helsinski University Hospital

    Helsinki, Finland

  • Hospital Clinic i Provincial de Barcelona

    Barcelona, Spain

  • Hospital Universitario 12 de octubre

    Madrid, Spain

  • Montpellier Hospital

    Montpellier, France

  • NHS Lothian

    Edinburgh, United Kingdom

  • Purpan Hospital

    Toulouse, France

  • Queen Elizabeth Hospital Birmingham

    Birmingham, United Kingdom

  • Queen Elizabeth University Hospital

    Glasgow, United Kingdom

  • Salzburg University Hopsital

    Salzburg, Austria

  • Turun yliopistollinen keskussairaala

    Turku, Finland

  • Universitätsklinikum Knappschaftskrankenhaus Bochum GmbH

    Bochum, Germany

  • Universitätsklinikum Schleswig-Holstein Campus Lübeck

    Lübeck, Germany