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Stent-Graft device under scrutiny for aortic aneurysm and dissection repair

NCT ID NCT06507865

Ongoing Disease control Sponsor: W.L.Gore & Associates Source: ClinicalTrials.gov ↗

First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time

Summary

This study tracks the safety and effectiveness of the GORE® TAG® Thoracic Branch Endoprosthesis, a stent-graft device used to treat aortic arch and descending aorta conditions such as aneurysms, dissections, and transections. Researchers will follow about 155 patients who receive the device as part of standard care, monitoring outcomes like technical success, device-related complications, and survival. The goal is to gather real-world data on how well the device performs over the medium term.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
GORE® TAG® Thoracic Branch Endoprosthesis (a stent-graft device)
What this could lead to
If successful, this study could confirm that the device is a safe and effective long-term option for treating complex aortic conditions, potentially reducing the need for open surgery.
What could go wrong
This is an observational registry, not a controlled trial, so results may not prove cause and effect. Risks include stroke, spinal cord injury, device migration, or need for additional procedures.

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Conditions

The condition(s) this trial relates to.

Aneurysm aortic aneurysm Aortic Aneurysm, Thoracoabdominal Aortic Dissection thoracic aortic aneurysm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANEURYSM DISSECTION, AORTIC TAA THORACOABDOMINAL AORTIC ANEURYSM THORACIC AORTIC ANEURYSM TRANSECTION AORTA

Contacts and locations

Locations

  • AOU Padova

    Padova, 35128, Italy

  • ASST Spedali Civili di Brescia

    Brescia, 25123, Italy

  • Amsterdam UMC

    Amsterdam, 1105 AZ, Netherlands

  • Evangelismos General Hospital

    Athens, 106 76, Greece

  • Hospital Universitario Miguel Servet

    Zaragoza, 50009, Spain

  • IRCCS Ospedale Policlinico San Martino

    Genova, 16132, Italy

  • Klinik für Gefäßmedizin, Universitätsklinikum Hamburg-Eppendorf

    Hamburg, Germany

  • Laiko General hospital of Athens

    Athens, 11527, Greece

  • Medizinische Universität Wien

    Vienna, A-1090, Austria

  • Policlinico di Sant'Orsola

    Bologna, 40138, Italy

  • Radboud UMC

    Nijmegen, 6525 GA, Netherlands

  • Rigshospitalet University Hospital

    Copenhagen, 2100, Denmark

  • Skane University Hospital

    Malmö, 205 02, Sweden

  • St Mary's Hospital

    London, W2 1NY, United Kingdom

  • St Thomas' Hospital

    London, SE1 7EH, United Kingdom

  • University of Heidelberg

    Heidelberg, 69120, Germany

  • Universitätsklinikum Münster

    Münster, 48149, Germany

  • Universitätsklinikum Schleswig-Holstein

    Kiel, 24105, Germany

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