THORACIC AORTIC ANEURYSM

This study tests whether spironolactone, a medication that blocks aldosterone, can reduce stiffness in the aorta for people with a thoracic aortic aneurysm. About 50 adults with an enlarged aorta will receive either spironolactone or a placebo for a short time. The goal is to see…

This study is tracking 1,000 people who receive Terumo aortic stent grafts to repair aneurysms in the abdomen or chest. Researchers are monitoring how well the devices work and any complications, like death related to the aorta. It is an observational registry, meaning no new tre…

This study tests a new surgical technique called B-SAFER for people with complex aortic disease affecting multiple segments of the aorta. The procedure combines open surgery with a modified stent graft to repair the aortic arch and descending aorta in one operation. Researchers a…

This study gathers medical images and health data from 5000 people who had TEVAR (a type of aorta surgery) to create computer models called digital twins. These models simulate the surgery to help doctors choose the best device and predict problems. The goal is to make planning m…

This study follows 320 people with small-to-moderate thoracic aortic aneurysms for up to 5 years. Researchers will track major complications like rupture or need for surgery, and look for factors such as high blood pressure or sleep problems that might speed up aneurysm growth. T…

This study looks at whether measuring a substance called presepsin in the blood during and after aorta surgery can help doctors decide when to use antibiotics. About 50 adults having surgery for a thoracic aortic aneurysm or dissection will take part. The goal is to see if presep…