New hybrid aortic repair technique aims to save lives
NCT ID NCT04747626
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new surgical technique called B-SAFER for people with complex aortic disease affecting multiple segments of the aorta. The procedure combines open surgery with a modified stent graft to repair the aortic arch and descending aorta in one operation. Researchers are enrolling 590 participants to see if the approach is safe and effective, measuring outcomes like death, stroke, and successful sealing of the aortic damage.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
B-SAFER technique (physician-modified endovascular stent graft used during frozen elephant trunk repair)
What this could lead to
If successful, this could offer a safer, more effective surgical option for people with complex aortic disease, potentially reducing death and stroke rates.
What could go wrong
This is an early feasibility study at a single center, not yet randomized or compared to standard care. The modified device may carry unknown risks like endoleak or graft failure.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Locations
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Cleveland Clinic
RECRUITINGCleveland, Ohio, 44195, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••