New coil device aims to seal brain aneurysms without surgery

NCT ID NCT04057352

Ongoing Disease control Sponsor: Stryker Neurovascular Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing a new device called the Citadel Embolization Device, a coil used to block blood flow in brain aneurysms. It involves 150 adults aged 18-80 with unruptured or recently ruptured wide-neck aneurysms. The goal is to see if the device safely and effectively seals the aneurysm, preventing future bleeding.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Citadel Embolization Device (a coil used to block blood flow in brain aneurysms)
What this could lead to: If successful, this device could offer a safer, less invasive way to treat wide-neck brain aneurysms, potentially reducing the need for surgery.
What could go wrong: This is a single-arm study with no comparison group, so results may be less definitive. Risks include stroke or incomplete aneurysm closure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

brain aneurysm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

UNRUPTURED WIDE-NECK ANEURYSMS

Contacts and locations

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Locations

Baptist Health

Jacksonville, Florida, 32207, United States
Baptist Health

Lexington, Kentucky, 40503, United States
California Pacific Medical Center

San Francisco, California, 94114, United States
Cedars-Sinai Medical Center

Los Angeles, California, 90048, United States
Cleveland Clinic

Cleveland, Ohio, 44195, United States
Indiana Methodist

Indianapolis, Indiana, 46202, United States
John Muir Health

Walnut Creek, California, 94598, United States
Kansas University Medical Center

Kansas City, Kansas, 66160, United States
McLaren Health Center

Flint, Michigan, 48532, United States
Montefiore Medical Center

New York, New York, 10467, United States
Northwestern University

Chicago, Illinois, 60611, United States
RIA Neurovascular

Englewood, Colorado, 80113, United States
Spectrum Health

Grand Rapids, Michigan, 49503, United States
Tampa General Hospital

Tampa, Florida, 33606, United States
Thomas Jefferson University

Philadelphia, Pennsylvania, 19107, United States
UCSF Medical Center

San Francisco, California, 94143, United States
UMass Memorial Health

Worcester, Massachusetts, 01605, United States
University of Florida

Gainesville, Florida, 32608, United States
University of Kentucky

Lexington, Kentucky, 40506, United States
University of Miami/Jackson Memorial

Miami, Florida, 33136, United States
University of Pennsylvania Hospital

Philadelphia, Pennsylvania, 19104, United States
University of Washington

Seattle, Washington, 98104, United States
Washington University

St Louis, Missouri, 63110, United States
Weill Cornell

New York, New York, 10021, United States
West Virginia University Hospital

Morgantown, West Virginia, 26506, United States