Brain aneurysm device under Real-World watch: will it hold up?

NCT ID NCT05071963

Ongoing Disease control Sponsor: Medtronic Neurovascular Clinical Affairs Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Aug 11, 2026 · Updated 3 times

Summary

This study follows 246 people who received the Pipeline Shield device to treat brain aneurysms. The device is a small mesh tube that blocks blood flow to the aneurysm, reducing rupture risk. Researchers are checking how well the aneurysm seals, whether the artery narrows, and if repeat treatment is needed within one year.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Pipeline™ Flex Embolization Device with Shield Technology™ (a device used to block blood flow to brain aneurysms)
What this could lead to: If successful, this study could confirm that the Pipeline Shield device is a safe and effective option for treating brain aneurysms in everyday medical practice.
What could go wrong: This is an observational study, not a controlled trial, so results may not prove the device is better than other treatments. Risks include incomplete aneurysm sealing or artery narrowing.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

brain aneurysm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INTRACRANIAL ANEURYSM

Contacts and locations

Locations

Baptist Medical Center Jacksonville

Jacksonville, Florida, 32207, United States
Baylor Scott & White Research Institute

Dallas, Texas, 75201, United States
Emory University Hospital

Atlanta, Georgia, 30322, United States
Endeavor Health - Evanston Hospital

Evanston, Illinois, 60201, United States
Geisinger Medical Center

Danville, Pennsylvania, 17822-9800, United States
Hospital of the University of Pennsylvania

Philadelphia, Pennsylvania, 19104, United States
Montefiore Medical Center

New York, New York, 10467-2401, United States
NYU Langone Medical Center

New York, New York, 10016-6402, United States
Norton Healthcare

Louisville, Kentucky, 40202, United States
Oklahoma (OU) University Medical Center

Oklahoma City, Oklahoma, 73104, United States
Prisma Health

Greenville, South Carolina, 29605, United States
The Cleveland Clinic Foundation

Cleveland, Ohio, 44195, United States
University of Alabama at Birmingham

Birmingham, Alabama, 35294, United States
University of Utah Hospital

Salt Lake City, Utah, 84132-0001, United States
Washington University in Saint Louis

St Louis, Missouri, 63130, United States
Yale New Haven Hospital

New Haven, Connecticut, 06510, United States

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