Brain aneurysm
MONDO:0005291A congenital or acquired aneurysm within the cranium.
Also known as: intracranial aneurysm
138 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
-
New stent shows promise in sealing brain aneurysms
Disease control CompletedThis study tested a new device called SINOMED IAS in 203 people with wide-necked brain aneurysms. The device is a stent placed inside the artery to block blood flow into the aneurysm, helping it heal. The main goal was to see if the aneurysm was successfully closed at 6 months af…
Phase: NA • Sponsor: Sinomed Neurovita Technology Inc. • Aim: Disease control
Last updated Jul 15, 2026 00:00 UTC
-
Stent shows promise for brain aneurysm repair
Disease control CompletedThis study tested a special stent designed to divert blood flow away from brain aneurysms, helping them heal. It involved 143 people with unruptured, wide-necked aneurysms. The main goal was to see if the stent could completely seal the aneurysm within a year without causing majo…
Phase: NA • Sponsor: Sinomed Neurovita Technology Inc. • Aim: Disease control
Last updated Jul 15, 2026 00:00 UTC
-
Brain aneurysm coils put to the test in largest Real-World study
Disease control CompletedThis study tracked 723 people with brain aneurysms treated using MICRUSFRAME and GALAXY coils, sometimes with a PulseRider device. The goal was to see how well the coils blocked the aneurysm and kept it closed after 12 months. Researchers collected data from real hospital setting…
Phase: NA • Sponsor: Cerenovus, Part of DePuy Synthes Products, Inc. • Aim: Disease control
Last updated Jul 11, 2026 00:00 UTC
-
Tighter blood pressure control may reduce brain aneurysm risk
Disease control CompletedThis study tested whether lowering blood pressure more aggressively than standard care reduces the risk of rupture or growth of unruptured brain aneurysms. 577 Chinese adults with small, unruptured aneurysms and high blood pressure were randomly assigned to keep their blood press…
Phase: NA • Sponsor: Beijing Tiantan Hospital • Aim: Disease control
Last updated Jul 01, 2026 00:00 UTC
-
New device aims to seal brain aneurysms without surgery
Disease control CompletedThis study tested a device called Trenza for treating brain aneurysms. It involved 150 people aged 18 to 80 with a single saccular aneurysm between 6 and 12 mm. The goal was to see if the device could safely block the aneurysm from blood flow and prevent strokes.
Sponsor: Stryker Neurovascular • Aim: Disease control
Last updated Jun 27, 2026 13:03 UTC
-
New stent shows promise for tricky brain aneurysms
Disease control CompletedThis study tested a special stent (Enterprise 2) used with coils to treat wide-neck brain aneurysms. Ten adults with this condition received the procedure. Researchers checked if the stent stayed in place, shortened, or narrowed over time. The goal was to see if this device can s…
Sponsor: Methodist Health System • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
-
New wire aims to make brain surgery safer
Disease control CompletedThis study tested a new medical wire, called the Tarvos Microguidewire, used during surgery on blood vessels in the brain. The wire helps doctors guide other tools to the right spot. Researchers looked back at records of 121 patients who had this wire used in their surgery for co…
Sponsor: Keuro MedTech • Aim: Disease control
Last updated Jun 27, 2026 12:03 UTC
-
New stents aim to seal dangerous brain aneurysms
Disease control CompletedThis study tested two stent systems (Neuroform EZ and Neuroform Atlas) used with coils to treat wide-neck brain aneurysms. Wide-neck aneurysms are hard to seal because coils can fall out. The stents act like a scaffold to keep coils in place. 30 adults with unruptured, wide-neck …
Phase: NA • Sponsor: Methodist Health System • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
-
Special coating on brain stent may reduce dangerous narrowing
Disease control CompletedThis study tested whether a coated stent (Derivo 2 heal) causes less narrowing inside the artery than an uncoated stent after treating brain aneurysms. 21 adults with unruptured aneurysms in the internal carotid artery were randomly assigned to receive one of the two stents. Rese…
Phase: NA • Sponsor: Universität des Saarlandes • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
-
New device aims to make brain aneurysm coiling safer
Disease control CompletedThis study tested a temporary device called Comaneci that helps doctors place coils in wide-necked brain aneurysms. 90 patients were treated and followed for up to 6 months to check safety and how well the aneurysm was sealed. The goal was to see if the device works well in every…
Sponsor: Rapid Medical • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
-
New brain aneurysm stent shows promise in clinical trial
Disease control CompletedThis study tested a new stent called Tonbridge for treating brain aneurysms (weak spots in blood vessels). It involved 204 people aged 18 to 80 who needed a stent to help place coils inside the aneurysm. The goal was to see if the new stent works as well as an existing device at …
Phase: NA • Sponsor: Ton-Bridge Medical Tech. Co., Ltd • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
-
New brain aneurysm device shows promise in 142-Patient trial
Disease control CompletedThis study tested a new medical device called the Tonbridge flow diverter to treat brain aneurysms (weak spots in blood vessels). The device is placed inside the artery to redirect blood flow away from the aneurysm, helping it heal. The trial included 142 people aged 18 to 80 wit…
Phase: NA • Sponsor: Ton-Bridge Medical Tech. Co., Ltd • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
-
New brain aneurysm coil shows promise in early safety trial
Disease control CompletedThis study tested a new expandable coil system for treating medium to large brain aneurysms (both ruptured and unruptured) in 13 adults. The goal was to see if the coil is safe and effectively blocks blood flow into the aneurysm. Results focused on serious side effects and how we…
Phase: NA • Sponsor: Shape Memory Medical, Inc. • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
-
Shorter blood thinner course after aneurysm coiling may be just as safe
Disease control CompletedThis study looked at 528 adults who had a brain aneurysm fixed with a stent and coils. It compared taking two blood thinners for 6 months versus 12 months after the procedure. The goal was to see if the shorter course could prevent blood clots just as well while reducing bleeding…
Phase: PHASE4 • Sponsor: Seoul National University Bundang Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
-
Brain aneurysm showdown: which treatment is safer and cheaper?
Disease control CompletedThis study compared two procedures for treating unruptured brain aneurysms: traditional coiling (using tiny coils to block blood flow) and a newer method using a flow diverter stent. 91 adults with specific types of aneurysms took part. The goal was to see which treatment works b…
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
-
Could a simple drug make brain aneurysm surgery safer?
Disease control CompletedThis study tested whether giving the drug tirofiban during stent or flow diverter procedures for unruptured brain aneurysms could reduce the number of small brain injuries seen on MRI after surgery. 192 adults aged 18-80 took part. The goal was to see if tirofiban works better th…
Phase: PHASE2, PHASE3 • Sponsor: Beijing Tiantan Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
-
New coils aim to seal brain aneurysms safely
Disease control CompletedThis study looked at how safe and effective the OPTIMA coil system is for treating brain aneurysms. Researchers followed 300 patients across Europe for up to 12 months after the coiling procedure. They tracked complications like bleeding, blood clots, and the need for repeat trea…
Sponsor: Balt Extrusion • Aim: Disease control
Last updated Jun 26, 2026 17:36 UTC
-
Pompe disease may raise risk of brain aneurysms, new study investigates
Knowledge-focused CompletedThis study investigates whether people with late-onset Pompe disease have a higher risk of severe blood vessel problems in the brain and aorta. Researchers will collect medical and genetic data from adults with Pompe disease and from those who have had a brain aneurysm or bleedin…
Sponsor: Hospitales Universitarios Virgen del Rocío • Aim: Knowledge-focused
Last updated Jul 08, 2026 00:00 UTC
-
Brain aneurysm patients: how does clopidogrel affect you?
Knowledge-focused CompletedThis completed study looked at 208 people with cerebral aneurysms who were treated with clopidogrel, a blood thinner. Researchers wanted to find out how many patients are overly sensitive to the drug and what happens to them. The goal is to better understand risks and improve car…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
-
Eye test may spot brain trouble
Knowledge-focused CompletedThis small pilot study tested whether a non-invasive eye scan called OCTA can detect changes in the brain related to stroke and other neurological conditions. Researchers compared eye scans from 7 people with brain diseases and healthy volunteers. The goal was to gather early dat…
Sponsor: University of Texas Southwestern Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
-
Which anesthesia is safer for brain aneurysm repair? new study investigates
Knowledge-focused CompletedThis study compared two types of anesthesia—propofol alone versus a mix of propofol and ketamine—in 46 adults having elective surgery for unruptured brain aneurysms. Researchers measured the diameter of the optic nerve sheath (a marker of brain pressure) at several points during …
Sponsor: Ankara City Hospital Bilkent • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
-
Massive study reveals best approaches for silent brain aneurysms
Knowledge-focused CompletedThis completed study followed over 31,000 people in China who had unruptured brain aneurysms (a bulge in a blood vessel that hasn't burst). Researchers compared four approaches: simply monitoring the aneurysm, surgical clipping, coil embolization, or flow diversion. The goal was …
Sponsor: Beijing Tiantan Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
-
Simple nurse checklist could predict brain bleeds after stroke therapy
Knowledge-focused CompletedThis study tested a 12-item checklist used by nurses to predict neurological complications like bleeding or re-blockage after endovascular therapy for stroke or aneurysms. Researchers compared 213 patients who were checked with the list to 213 who received standard care. The goal…
Phase: NA • Sponsor: West China Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
-
Brain aneurysm blood flow software tested for predicting stent success
Knowledge-focused CompletedThis study tested a software tool called AneurysmFlow that measures blood flow in brain aneurysms. The goal was to see if it can predict whether an aneurysm will fully close 12 months after a stent is placed. 132 adults with unruptured brain aneurysms participated. The tool is al…
Sponsor: Philips Clinical & Medical Affairs Global • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC