Brain aneurysm coils put to the test in largest Real-World study

NCT ID NCT03642639

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tracked 723 people with brain aneurysms treated using MICRUSFRAME and GALAXY coils, sometimes with a PulseRider device. The goal was to see how well the coils blocked the aneurysm and kept it closed after 12 months. Researchers collected data from real hospital settings to understand the devices' everyday performance.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

MICRUSFRAME and GALAXY coils (medical devices used to block blood flow to an aneurysm)

What this could lead to

If successful, this could confirm that these coils are a safe and effective option for treating brain aneurysms in everyday medical practice.

What could go wrong

This is an observational registry, not a controlled trial, so results may not prove the coils are better than other treatments. Some aneurysms may still reopen over time.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Aneurysm brain aneurysm intracranial berry aneurysm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Aichi Medical University Hospital

    Aichi, Japan

  • Algemeen Ziekenhuis Groeninge

    Kortrijk, Belgium

  • Baptist Medical Center

    Jacksonville, Florida, 32207, United States

  • Centre Hospitalier Regional Universitaire de Tours

    Tours, France

  • Centre Hospitalier Universitaire d'Amiens Picardie

    Amiens, France

  • Centre Hospitalier Universitaire de Bordeaux

    Bordeaux, France

  • Centro Hospitalar de Vila Nova de Gaia

    Porto, Portugal

  • Duke University Medical Center

    Durham, North Carolina, 27710, United States

  • Galilee Hospital Naharyia

    Nahariya, Israel

  • Geisinger Clinic

    Danville, Pennsylvania, 17822, United States

  • Greenville Health System

    Greenville, South Carolina, 61103, United States

  • Hopital Roger Salengro-Centre Hospitalier Universitaire de Lille

    Lille, France

  • Hopitaux Universitaires de Geneve

    Geneva, Switzerland

  • Hospital Universitari i Politecnic La Fe

    Valencia, Spain

  • Javon Bea Hospital

    Rockford, Illinois, 61103, United States

  • Kohnan Hospital

    Sendai, Japan

  • Maine Medical Center

    Scarborough, Maine, 04074, United States

  • Medical University of South Carolina

    Charleston, South Carolina, 29425, United States

  • Meihokai Yokohama Shin-Toshi Brain Orthopedic Hospital

    Yokohama, Japan

  • Memorial Health University

    Savannah, Georgia, 31405, United States

  • Mercy Health St. Vincent Medical Center

    Toledo, Ohio, 43604, United States

  • Mercy San Juan Medical Center

    Carmichael, California, 95608, United States

  • Mount Sinai Hospital

    New York, New York, 10029, United States

  • National Hospital Organization Osaka National Hospital

    Osaka, Japan

  • Norton Healthcare

    Louisville, Kentucky, 40241, United States

  • Okayama University Hospital

    Okayama, Japan

  • Oregon Health and Science University

    Portland, Oregon, 97239, United States

  • Ospedale Cannizzaro

    Sicily, Italy

  • Ospedale Niguarda Ca' Granda

    Milan, Italy

  • Policlinico Tor Vergata

    Roma, Italy

  • Praticien Hospitalier Université de Lorraine

    Nancy, France

  • Rush University

    Chicago, Illinois, 60612, United States

  • St. Louis University

    St Louis, Missouri, 63110, United States

  • Stony Brook University

    Stony Brook, New York, 11794, United States

  • Tennessee Interventional and Imaging Associates

    Chattanooga, Tennessee, 37403, United States

  • Texas Stroke Institute

    Plano, Texas, 75075, United States

  • Tominaga Hospital

    Osaka, Japan

  • Universitatsklinikum Schleswig Holstein

    Lübeck, Germany

  • University Hospital Zurich

    Zurich, Switzerland

  • University of Arizona

    Tucson, Arizona, 85724, United States

  • University of Buffalo

    Buffalo, New York, 14075, United States

  • University of California Irvine

    Orange, California, 92868, United States

  • University of Florida

    Gainesville, Florida, 32608, United States

  • University of Illinois

    Chicago, Illinois, 60612, United States

  • University of Massachusetts

    Worcester, Massachusetts, 01655, United States

  • University of Miami

    Miami, Florida, 33136, United States

  • University of Oklahoma Health Sciences Center

    Oklahoma City, Oklahoma, 73104, United States

  • University of Tennessee

    Knoxville, Tennessee, 37920, United States

  • University of Utah

    Salt Lake City, Utah, 84132, United States

  • University of Virginia

    Charlottesville, Virginia, 22908, United States

  • Westchester Medical Center

    Valhalla, New York, 10595, United States