Aphasia
MONDO:0000598A language disorder that involves an acquired impairment of any language modality such as producing or comprehending spoken or written language.
105 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
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New practice method aims to help stroke survivors find lost words
Disease control CompletedThis study tests a computer-based practice method to help people with aphasia—a language disorder often caused by stroke—retrieve words they know but struggle to say or understand. Participants practice naming pictures with or without cues, repeating items until they reach a set …
Phase: NA • Sponsor: Albert Einstein Healthcare Network • Aim: Disease control
Last updated Jul 10, 2026 00:00 UTC
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Tailored treatment shows promise for slowing early dementia
Disease control CompletedThis study tested whether a personalized treatment plan—based on each person's test results—works better than standard care for people with mild cognitive impairment or early-stage dementia. 73 adults aged 45-76 took part, receiving either the tailored plan or usual care for 9 mo…
Phase: PHASE3 • Sponsor: Alzheimer's Prevention and Reversal Project, Inc. • Aim: Disease control
Last updated Jun 27, 2026 09:05 UTC
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Shocking the brain back to reading: new hope for aphasia
Symptom relief CompletedThis study tested whether adding a gentle brain stimulation technique called tDCS to a reading therapy (PMT) could help stroke survivors with aphasia read better. Six people with chronic aphasia took part. The goal was to see if the combination improved reading accuracy more than…
Phase: NA • Sponsor: Kessler Foundation • Aim: Symptom relief
Last updated Jun 27, 2026 12:30 UTC
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Zapping the brain to unlock lost words: a new hope for stroke survivors?
Symptom relief CompletedThis study tested a gentle, non-invasive brain stimulation technique called tDCS in 14 people who had a stroke at least a year ago and still have trouble finding words (aphasia). The goal was to see if stimulating a key language area could improve their ability to name pictures a…
Phase: NA • Sponsor: Adrian Guggisberg • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Intensive talk therapy boosts speech after stroke, study finds
Symptom relief CompletedThis study tested whether 3 weeks of intensive language therapy (at least 2 hours daily, 5 days a week) helps people with long-term aphasia after a stroke communicate better in everyday situations. 156 participants with aphasia for at least 6 months were assigned to either immedi…
Phase: NA • Sponsor: University Hospital Muenster • Aim: Symptom relief
Last updated Jun 27, 2026 12:25 UTC
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New Chat-Based therapy helps stroke survivors communicate better
Symptom relief CompletedThis study tested the PACE technique, a therapy that encourages people with aphasia to use any form of communication—like gestures, drawing, or writing—to get their message across. Sixteen adults aged 45 to 65 with mild to moderate aphasia took part. Half received PACE plus stand…
Phase: NA • Sponsor: Riphah International University • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
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Zapping the brain to restore words: small study tests tACS for aphasia
Symptom relief CompletedThis small pilot study tested whether a gentle electrical current applied to the brain (tACS) could improve naming ability in 11 people with chronic aphasia after a stroke. Participants received either real or sham stimulation during language training over two weeks. The goal was…
Phase: NA • Sponsor: QVITI S.A. • Aim: Symptom relief
Last updated Jun 27, 2026 12:04 UTC
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New app aims to reboot language after stroke
Symptom relief CompletedThis study tested an app called iTalkBetter for people who have trouble finding words after a stroke. 31 participants used the app to practice naming specific items. The goal was to see if the app could improve word retrieval for those practiced items. This small trial helps unde…
Phase: NA • Sponsor: University College, London • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC
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Zapping the brain to find lost words: new hope for TBI patients
Symptom relief CompletedThis study tested a gentle electric current (tDCS) on the brain to see if it could help people with a past traumatic brain injury find words more easily. Fourteen adults with long-term word-finding problems took part. They received either real or fake stimulation while doing memo…
Phase: NA • Sponsor: The University of Texas at Dallas • Aim: Symptom relief
Last updated Jun 27, 2026 09:07 UTC
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Exercise might help stroke survivors find their words again
Symptom relief CompletedThis study looked at whether a high-intensity exercise program is safe and helpful for people with aphasia (trouble speaking or understanding language) after a stroke. Twelve stroke survivors took part in either a low-intensity or high-intensity exercise program. Researchers meas…
Phase: NA • Sponsor: University of California, Berkeley • Aim: Symptom relief
Last updated Jun 27, 2026 09:06 UTC
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Zapping the brain to find lost words: tiny study tests tDCS for TBI
Symptom relief CompletedThis small study tested whether a gentle electric current applied to the scalp (tDCS) could improve word-finding in 5 civilians who had a traumatic brain injury more than a year ago. Participants received both real and sham stimulation to see if the real treatment boosted verbal …
Phase: NA • Sponsor: The University of Texas at Dallas • Aim: Symptom relief
Last updated Jun 27, 2026 09:01 UTC
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Zapping the brain to help stroke survivors speak again
Symptom relief CompletedThis study tested whether a gentle, non-invasive brain stimulation called tDCS could make speech therapy work better for people with aphasia (trouble speaking or understanding language) after a stroke. 23 adults who were at least 6 months past their stroke received speech therapy…
Phase: NA • Sponsor: Syracuse University • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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Painting your way back to speech: art therapy shows promise for aphasia after stroke
Symptom relief CompletedThis study tested whether adding art therapy to standard speech rehab could help people who recently had a stroke and now have trouble speaking (aphasia). Fifteen participants received 12 art therapy sessions alongside their usual therapy. Researchers used brain scans to see if a…
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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App helps dementia patients recall loved Ones' names
Symptom relief CompletedThis study tested a web-based app called Gotcha! designed to help people with mild-to-moderate dementia remember names of people they know. 48 participants practiced daily for 6 weeks using a tablet at home. The goal was to see if the therapy improves name recall and whether it c…
Phase: NA • Sponsor: University College, London • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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Zapping the brain to restore speech after stroke
Symptom relief CompletedThis study tested whether a gentle brain stimulation technique called tACS, combined with speech training, can improve the ability to repeat words in people who had a stroke. 28 adults with aphasia received either real or fake stimulation for 20 minutes daily over 10 days. Resear…
Phase: NA • Sponsor: Ke Dong, MD • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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Zapping the brain to help stroke survivors find words again
Symptom relief CompletedThis small study tested whether adding mild brain stimulation (tDCS) to a computer-based naming therapy helps Cantonese-speaking adults with aphasia after stroke find words more quickly and accurately. Six participants completed two 5-day therapy blocks—one with real stimulation …
Phase: NA • Sponsor: The University of Hong Kong • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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Electric zaps to the brain may help veterans remember words
Symptom relief CompletedThis study tested a safe, noninvasive treatment for memory and word-finding problems in Gulf War veterans. 93 veterans received either real or fake (sham) brain stimulation over 10 sessions. The goal was to see if the stimulation improved their ability to recall words and speak m…
Phase: NA • Sponsor: The University of Texas at Dallas • Aim: Symptom relief
Last updated Jun 27, 2026 08:11 UTC
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Brain zaps may help stroke survivors find their words again
Symptom relief CompletedThis pilot study tested whether combining a mild brain stimulation technique (tDCS) with intensive language therapy can help people with non-fluent aphasia after a stroke. Ten participants received both real and sham stimulation during therapy sessions. The goal was to see if the…
Phase: NA • Sponsor: University of Minnesota • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Stroke speech therapy: finding the right dose
Symptom relief CompletedThis study tested speech entrainment therapy (SET) in 80 people with non-fluent aphasia after a stroke. Participants practiced speaking along with an audio-visual computer program for 3, 4.5, or 6 weeks, or received no therapy. The goal was to find the best duration for lasting i…
Phase: PHASE2 • Sponsor: Medical University of South Carolina • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
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New Hand-Gesture therapy may help stroke survivors find words again
Symptom relief CompletedThis study tested a behavioral therapy called Intention Treatment for Anomia in 32 stroke survivors with aphasia (language impairment). The therapy uses a left-hand circular gesture to engage the brain's intention mechanisms and improve word retrieval. Researchers looked at how o…
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Jun 27, 2026 07:55 UTC
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Can training dogs help people with aphasia find their voice?
Symptom relief CompletedThis study tested a program where adults with aphasia (a language disorder often from stroke) learn to train dogs using positive reinforcement. The goal was to see if this boosts quality of life, confidence, and social engagement. Seventeen participants completed the program, and…
Phase: NA • Sponsor: Albert Einstein Healthcare Network • Aim: Symptom relief
Last updated Jun 27, 2026 07:54 UTC
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Zapping the brain to save speech: new hope for aphasia?
Symptom relief CompletedThis study tested whether a gentle electrical current applied to the brain (tDCS) can improve language when combined with speech therapy in people with primary progressive aphasia (PPA), a condition that slowly damages language abilities. 76 adults with two types of PPA received …
Phase: PHASE2 • Sponsor: University of Pennsylvania • Aim: Symptom relief
Last updated Jun 27, 2026 07:54 UTC
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Shocking the brain back to speech: new hope for stroke survivors
Symptom relief CompletedThis study tested whether combining transcranial magnetic stimulation (TMS) with language therapy helps people with chronic aphasia—a language disorder after stroke—speak better. 86 participants received either real TMS or a sham version, plus language therapy, over two weeks. Th…
Phase: PHASE2 • Sponsor: H. Branch Coslett • Aim: Symptom relief
Last updated Jun 27, 2026 07:54 UTC
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Zapping the brain to find lost words: new hope for stroke survivors?
Symptom relief CompletedThis study tested whether a gentle electrical current applied to the scalp (tDCS) during speech therapy could help people with chronic aphasia—a language disorder after stroke—recover their ability to name objects and read words. Twenty-five adults with long-term aphasia received…
Phase: NA • Sponsor: Medical College of Wisconsin • Aim: Symptom relief
Last updated Jun 27, 2026 07:53 UTC
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Talking along: simple speech practice shows promise for aphasia
Symptom relief CompletedThis study tested a speech therapy technique called speech entrainment, where people with aphasia practice speaking along with a recorded voice in real time. Thirty adults with aphasia participated, either in person or at home. The goal was to see if this practice improves how in…
Phase: NA • Sponsor: Albert Einstein Healthcare Network • Aim: Symptom relief
Last updated Jun 26, 2026 18:18 UTC
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Brain scans reveal how language therapy rewires Stroke-Damaged brains
Knowledge-focused CompletedThis study investigates how different language treatments affect both language skills and brain function in people with aphasia, a condition that impairs the ability to speak, understand, read, or write after a stroke. Participants will receive therapy targeting naming, spelling,…
Phase: NA • Sponsor: Northwestern University • Aim: Knowledge-focused
Last updated Jul 03, 2026 00:00 UTC
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Speech therapy frequency: does more mean better?
Knowledge-focused CompletedThis study examined how the frequency of speech therapy sessions affects speech and language outcomes in children. Researchers followed 39 children with speech or language disorders who were receiving individual therapy. They measured changes in articulation, vocabulary, and over…
Phase: NA • Sponsor: Connecticut Children's Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Brain wave study reveals how gestures connect minds after stroke
Knowledge-focused CompletedThis study looked at how the brains of people with aphasia (a language disorder after stroke) and healthy people work together during gestures. Using EEG, researchers measured brain synchronization while participants watched and copied different types of gestures. The goal was to…
Sponsor: IRCCS San Camillo, Venezia, Italy • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Tiny study hopes to match aphasia patients to the right word therapy
Knowledge-focused CompletedThis completed study with just 2 participants aimed to find out who responds best to two different word-finding therapies for aphasia. Both treatments focus on the sounds of words to improve naming. The goal is to learn which therapy helps which person, so future treatment can be…
Phase: NA • Sponsor: State University of New York at Buffalo • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC