Aphasia
MONDO:0000598A language disorder that involves an acquired impairment of any language modality such as producing or comprehending spoken or written language.
165 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
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New community program targets COPD and mental health together
Disease control CompletedThis completed trial in Xishui, China, tested a community-based program for 3,571 adults aged 35 and older who were at high risk for COPD and had mental health symptoms. The program included lung function tests, digital mental health support, smoking cessation help, and health ed…
Phase: NA • Sponsor: Peking Union Medical College • Aim: Disease control
Last updated Jun 27, 2026 13:03 UTC
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Tailored treatment shows promise for slowing early dementia
Disease control CompletedThis study tested whether a personalized treatment plan—based on each person's test results—works better than standard care for people with mild cognitive impairment or early-stage dementia. 73 adults aged 45-76 took part, receiving either the tailored plan or usual care for 9 mo…
Phase: PHASE3 • Sponsor: Alzheimer's Prevention and Reversal Project, Inc. • Aim: Disease control
Last updated Jun 27, 2026 09:05 UTC
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Can one doctor visit tackle both addiction and depression?
Disease control CompletedThis study tested whether a team-based care model can help people with both opioid use disorder and mental health issues like depression or anxiety. 254 adults in primary care received either full collaborative care for both conditions or just mental health support. The goal was …
Phase: NA • Sponsor: University of Washington • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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Mediterranean diet shows promise for metabolic health in psychiatric patients
Disease control CompletedThis completed study tested whether a Mediterranean diet could improve metabolic syndrome markers in 30 hospitalized adults with psychiatric conditions. Participants followed either a Mediterranean diet or a standard hospital diet for 8 weeks, then switched. Researchers measured …
Phase: NA • Sponsor: King Saud University • Aim: Disease control
Last updated Jun 26, 2026 15:01 UTC
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Counseling program aims to boost mental health and HIV prevention in young women
Symptom relief CompletedThis study tested a counseling program called Youth Friendship Bench SA for young women aged 18-25 in South Africa who had symptoms of depression, anxiety, or stress. The program included individual and group counseling sessions, plus optional text reminders. The goal was to see …
Phase: NA • Sponsor: University of California, San Francisco • Aim: Symptom relief
Last updated Jun 28, 2026 00:00 UTC
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Video game therapy shows promise for mental health
Symptom relief CompletedThis study tested whether a 4-week program using active video games (exergames) on the Nintendo Switch could help adults with mental illness feel better and stay motivated. Twelve participants were split into two groups: one played exergames, the other continued their usual routi…
Phase: NA • Sponsor: University of Salamanca • Aim: Symptom relief
Last updated Jun 27, 2026 12:35 UTC
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Shocking the brain back to reading: new hope for aphasia
Symptom relief CompletedThis study tested whether adding a gentle brain stimulation technique called tDCS to a reading therapy (PMT) could help stroke survivors with aphasia read better. Six people with chronic aphasia took part. The goal was to see if the combination improved reading accuracy more than…
Phase: NA • Sponsor: Kessler Foundation • Aim: Symptom relief
Last updated Jun 27, 2026 12:30 UTC
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Zapping the brain to unlock lost words: a new hope for stroke survivors?
Symptom relief CompletedThis study tested a gentle, non-invasive brain stimulation technique called tDCS in 14 people who had a stroke at least a year ago and still have trouble finding words (aphasia). The goal was to see if stimulating a key language area could improve their ability to name pictures a…
Phase: NA • Sponsor: Adrian Guggisberg • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Intensive talk therapy boosts speech after stroke, study finds
Symptom relief CompletedThis study tested whether 3 weeks of intensive language therapy (at least 2 hours daily, 5 days a week) helps people with long-term aphasia after a stroke communicate better in everyday situations. 156 participants with aphasia for at least 6 months were assigned to either immedi…
Phase: NA • Sponsor: University Hospital Muenster • Aim: Symptom relief
Last updated Jun 27, 2026 12:25 UTC
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New Chat-Based therapy helps stroke survivors communicate better
Symptom relief CompletedThis study tested the PACE technique, a therapy that encourages people with aphasia to use any form of communication—like gestures, drawing, or writing—to get their message across. Sixteen adults aged 45 to 65 with mild to moderate aphasia took part. Half received PACE plus stand…
Phase: NA • Sponsor: Riphah International University • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
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Zapping the brain to restore words: small study tests tACS for aphasia
Symptom relief CompletedThis small pilot study tested whether a gentle electrical current applied to the brain (tACS) could improve naming ability in 11 people with chronic aphasia after a stroke. Participants received either real or sham stimulation during language training over two weeks. The goal was…
Phase: NA • Sponsor: QVITI S.A. • Aim: Symptom relief
Last updated Jun 27, 2026 12:04 UTC
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New app aims to reboot language after stroke
Symptom relief CompletedThis study tested an app called iTalkBetter for people who have trouble finding words after a stroke. 31 participants used the app to practice naming specific items. The goal was to see if the app could improve word retrieval for those practiced items. This small trial helps unde…
Phase: NA • Sponsor: University College, London • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC
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Zapping the brain to find lost words: new hope for TBI patients
Symptom relief CompletedThis study tested a gentle electric current (tDCS) on the brain to see if it could help people with a past traumatic brain injury find words more easily. Fourteen adults with long-term word-finding problems took part. They received either real or fake stimulation while doing memo…
Phase: NA • Sponsor: The University of Texas at Dallas • Aim: Symptom relief
Last updated Jun 27, 2026 09:07 UTC
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Exercise might help stroke survivors find their words again
Symptom relief CompletedThis study looked at whether a high-intensity exercise program is safe and helpful for people with aphasia (trouble speaking or understanding language) after a stroke. Twelve stroke survivors took part in either a low-intensity or high-intensity exercise program. Researchers meas…
Phase: NA • Sponsor: University of California, Berkeley • Aim: Symptom relief
Last updated Jun 27, 2026 09:06 UTC
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Can peer support groups boost recovery in mental health?
Symptom relief CompletedThis study tested a 10-week peer support program called 'Paths to everyday life' for adults with mental health difficulties. Participants were randomly assigned to either the peer support group plus usual services, or usual services alone. The goal was to see if the program impro…
Phase: NA • Sponsor: Amager Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 09:01 UTC
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Zapping the brain to find lost words: tiny study tests tDCS for TBI
Symptom relief CompletedThis small study tested whether a gentle electric current applied to the scalp (tDCS) could improve word-finding in 5 civilians who had a traumatic brain injury more than a year ago. Participants received both real and sham stimulation to see if the real treatment boosted verbal …
Phase: NA • Sponsor: The University of Texas at Dallas • Aim: Symptom relief
Last updated Jun 27, 2026 09:01 UTC
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Zapping the brain to help stroke survivors speak again
Symptom relief CompletedThis study tested whether a gentle, non-invasive brain stimulation called tDCS could make speech therapy work better for people with aphasia (trouble speaking or understanding language) after a stroke. 23 adults who were at least 6 months past their stroke received speech therapy…
Phase: NA • Sponsor: Syracuse University • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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Painting your way back to speech: art therapy shows promise for aphasia after stroke
Symptom relief CompletedThis study tested whether adding art therapy to standard speech rehab could help people who recently had a stroke and now have trouble speaking (aphasia). Fifteen participants received 12 art therapy sessions alongside their usual therapy. Researchers used brain scans to see if a…
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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App helps dementia patients recall loved Ones' names
Symptom relief CompletedThis study tested a web-based app called Gotcha! designed to help people with mild-to-moderate dementia remember names of people they know. 48 participants practiced daily for 6 weeks using a tablet at home. The goal was to see if the therapy improves name recall and whether it c…
Phase: NA • Sponsor: University College, London • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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Zapping the brain to restore speech after stroke
Symptom relief CompletedThis study tested whether a gentle brain stimulation technique called tACS, combined with speech training, can improve the ability to repeat words in people who had a stroke. 28 adults with aphasia received either real or fake stimulation for 20 minutes daily over 10 days. Resear…
Phase: NA • Sponsor: Ke Dong, MD • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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Zapping the brain to help stroke survivors find words again
Symptom relief CompletedThis small study tested whether adding mild brain stimulation (tDCS) to a computer-based naming therapy helps Cantonese-speaking adults with aphasia after stroke find words more quickly and accurately. Six participants completed two 5-day therapy blocks—one with real stimulation …
Phase: NA • Sponsor: The University of Hong Kong • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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Electric zaps to the brain may help veterans remember words
Symptom relief CompletedThis study tested a safe, noninvasive treatment for memory and word-finding problems in Gulf War veterans. 93 veterans received either real or fake (sham) brain stimulation over 10 sessions. The goal was to see if the stimulation improved their ability to recall words and speak m…
Phase: NA • Sponsor: The University of Texas at Dallas • Aim: Symptom relief
Last updated Jun 27, 2026 08:11 UTC
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Brain zaps may help stroke survivors find their words again
Symptom relief CompletedThis pilot study tested whether combining a mild brain stimulation technique (tDCS) with intensive language therapy can help people with non-fluent aphasia after a stroke. Ten participants received both real and sham stimulation during therapy sessions. The goal was to see if the…
Phase: NA • Sponsor: University of Minnesota • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Can Man's best friend boost mental health? new study says maybe.
Symptom relief CompletedThis study tested a 10-session dog-assisted therapy program for 60 adults with severe mental illness. The goal was to see if spending time with trained therapy dogs could help participants build positive mental health behaviors like communication and socialization. Researchers me…
Phase: NA • Sponsor: Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
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Stroke speech therapy: finding the right dose
Symptom relief CompletedThis study tested speech entrainment therapy (SET) in 80 people with non-fluent aphasia after a stroke. Participants practiced speaking along with an audio-visual computer program for 3, 4.5, or 6 weeks, or received no therapy. The goal was to find the best duration for lasting i…
Phase: PHASE2 • Sponsor: Medical University of South Carolina • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
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New Hand-Gesture therapy may help stroke survivors find words again
Symptom relief CompletedThis study tested a behavioral therapy called Intention Treatment for Anomia in 32 stroke survivors with aphasia (language impairment). The therapy uses a left-hand circular gesture to engage the brain's intention mechanisms and improve word retrieval. Researchers looked at how o…
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Jun 27, 2026 07:55 UTC
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Can training dogs help people with aphasia find their voice?
Symptom relief CompletedThis study tested a program where adults with aphasia (a language disorder often from stroke) learn to train dogs using positive reinforcement. The goal was to see if this boosts quality of life, confidence, and social engagement. Seventeen participants completed the program, and…
Phase: NA • Sponsor: Albert Einstein Healthcare Network • Aim: Symptom relief
Last updated Jun 27, 2026 07:54 UTC
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Zapping the brain to save speech: new hope for aphasia?
Symptom relief CompletedThis study tested whether a gentle electrical current applied to the brain (tDCS) can improve language when combined with speech therapy in people with primary progressive aphasia (PPA), a condition that slowly damages language abilities. 76 adults with two types of PPA received …
Phase: PHASE2 • Sponsor: University of Pennsylvania • Aim: Symptom relief
Last updated Jun 27, 2026 07:54 UTC
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Shocking the brain back to speech: new hope for stroke survivors
Symptom relief CompletedThis study tested whether combining transcranial magnetic stimulation (TMS) with language therapy helps people with chronic aphasia—a language disorder after stroke—speak better. 86 participants received either real TMS or a sham version, plus language therapy, over two weeks. Th…
Phase: PHASE2 • Sponsor: H. Branch Coslett • Aim: Symptom relief
Last updated Jun 27, 2026 07:54 UTC
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Zapping the brain to find lost words: new hope for stroke survivors?
Symptom relief CompletedThis study tested whether a gentle electrical current applied to the scalp (tDCS) during speech therapy could help people with chronic aphasia—a language disorder after stroke—recover their ability to name objects and read words. Twenty-five adults with long-term aphasia received…
Phase: NA • Sponsor: Medical College of Wisconsin • Aim: Symptom relief
Last updated Jun 27, 2026 07:53 UTC
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Exercise on campus: a new hope for stressed students?
Symptom relief CompletedThis study tested a 6-week supervised physical activity program for university students dealing with mild-to-moderate mental health issues like stress, anxiety, or feeling isolated. Seventeen students took part in group exercise sessions including walking, aerobics, and strength …
Phase: NA • Sponsor: York St John University • Aim: Symptom relief
Last updated Jun 26, 2026 18:21 UTC
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Talking along: simple speech practice shows promise for aphasia
Symptom relief CompletedThis study tested a speech therapy technique called speech entrainment, where people with aphasia practice speaking along with a recorded voice in real time. Thirty adults with aphasia participated, either in person or at home. The goal was to see if this practice improves how in…
Phase: NA • Sponsor: Albert Einstein Healthcare Network • Aim: Symptom relief
Last updated Jun 26, 2026 18:18 UTC
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Brain scans reveal how language therapy rewires Stroke-Damaged brains
Knowledge-focused CompletedThis study investigates how different language treatments affect both language skills and brain function in people with aphasia, a condition that impairs the ability to speak, understand, read, or write after a stroke. Participants will receive therapy targeting naming, spelling,…
Phase: NA • Sponsor: Northwestern University • Aim: Knowledge-focused
Last updated Jul 03, 2026 00:00 UTC
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Can peers help others recover? small study tests new program
Knowledge-focused CompletedThis study tested whether a 10-week recovery program, co-led by a peer with mental illness and a professional, is feasible for people with mental illness in Taiwan. Twenty participants completed the program, which focused on recovery concepts, strengths, and goal setting. Researc…
Phase: NA • Sponsor: National Cheng-Kung University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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New web tool aims to get sick healthcare workers back on the job faster
Knowledge-focused CompletedThis study tested a web application called PRATICAdr 2.0, designed to help healthcare workers on sick leave due to common mental disorders like depression or anxiety return to work. The app helps coordinators track progress and improve communication. Researchers compared workers …
Phase: NA • Sponsor: Université du Québec a Montréal • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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AI therapists in training: can computers teach better counseling?
Knowledge-focused CompletedThis study tested whether artificial intelligence (AI) can realistically simulate conversations between a therapist and a person with a mental health problem. Researchers used 520 simulated sessions to see if the AI could follow proper therapy techniques. The goal is to use these…
Phase: NA • Sponsor: University Hospital, Basel, Switzerland • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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Brain scans and thinking tests aim to unlock secrets of Self-Harm
Knowledge-focused CompletedThis study looked at how thinking skills and brain activity differ in people who self-harm compared to those who don't. Researchers interviewed 316 adults and gave them thinking tests, with some also having brain scans. The goal was to better understand self-harm to help create m…
Sponsor: Region Skane • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:34 UTC
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Speech therapy frequency: does more mean better?
Knowledge-focused CompletedThis study examined how the frequency of speech therapy sessions affects speech and language outcomes in children. Researchers followed 39 children with speech or language disorders who were receiving individual therapy. They measured changes in articulation, vocabulary, and over…
Phase: NA • Sponsor: Connecticut Children's Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Brain wave study reveals how gestures connect minds after stroke
Knowledge-focused CompletedThis study looked at how the brains of people with aphasia (a language disorder after stroke) and healthy people work together during gestures. Using EEG, researchers measured brain synchronization while participants watched and copied different types of gestures. The goal was to…
Sponsor: IRCCS San Camillo, Venezia, Italy • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Peer support after psychiatric stay shows promise in small VA study
Knowledge-focused CompletedThis study tested a program called Recovery Bridge, where trained peer specialists (people with lived experience of mental illness) helped veterans leaving a psychiatric hospital connect to outpatient care and community life. Fifteen veterans took part to see if the program was f…
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Heart and mind: new study explores the hidden links between cardiovascular disease and mental illness
Knowledge-focused CompletedThis completed study looked at 400 people with both heart disease and a mental health condition (like depression or anxiety). Researchers used questionnaires, blood tests, and imaging to find shared risk factors and biological markers. The goal was to better understand how these …
Sponsor: Ningbo No. 1 Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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Can training reduce stigma in healthcare? new study tests Anti-Bias program
Knowledge-focused CompletedThis study tested whether an anti-stigma training program for healthcare providers improves attitudes toward people with mental illness or substance use problems. About 485 staff and clients from six health centers took part, with three centers receiving the training and three no…
Phase: NA • Sponsor: Centre for Addiction and Mental Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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Sleep struggles widespread in psychiatric wards
Knowledge-focused CompletedThis study looked at how often insomnia occurs in people hospitalized for psychiatric conditions. Researchers checked 427 patients at 11 hospitals in Switzerland and Germany. They also explored whether age, gender, or type of disorder made insomnia more likely.
Sponsor: University of Bern • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:03 UTC
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Can doing meaningful activities boost recovery in mental illness? new study says maybe.
Knowledge-focused CompletedThis study tested an 8-month program called 'Meaningful Activities and Recovery' (MA&R) for people with mental illness. The program helps people take part in activities that matter to them. 139 adults took part to see if the program improves activity engagement, recovery, and qua…
Phase: NA • Sponsor: Amager Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Can a training program help therapy interns talk better with patients?
Knowledge-focused CompletedThis study tested a program called iCOT to improve how occupational therapy interns communicate with patients in mental health settings. The program included online training and feedback from patients, supervisors, and experts. Researchers compared interns who received iCOT to da…
Phase: NA • Sponsor: Chang Gung Memorial Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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Did a simple phone call keep chronic patients out of the hospital?
Knowledge-focused CompletedThis study tested whether a systematic phone call from a medical student, supervised by a general practitioner, could reduce hospitalizations in patients with chronic heart or mental health conditions during the COVID-19 lockdown in France. Over 22,000 patients aged 70 and older …
Phase: NA • Sponsor: University Hospital, Tours • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Study aims to make mental health support for kids more efficient and affordable
Knowledge-focused CompletedThis study tested different parts of a family navigation program to see which ones work best for helping low-income and minority families get mental health services for their children. 312 children aged 3-12 who showed signs of behavioral health concerns took part. The goal was t…
Phase: NA • Sponsor: Boston Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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AI could revolutionize online therapy by predicting who benefits most
Knowledge-focused CompletedThis study used artificial intelligence to predict how engaged people would be in online therapy and how much their symptoms would improve. Researchers analyzed data from over 6,600 adults who took part in a digital psychotherapy program. The goal was to create fair and accurate …
Sponsor: University Hospital, Basel, Switzerland • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Tiny study hopes to match aphasia patients to the right word therapy
Knowledge-focused CompletedThis completed study with just 2 participants aimed to find out who responds best to two different word-finding therapies for aphasia. Both treatments focus on the sounds of words to improve naming. The goal is to learn which therapy helps which person, so future treatment can be…
Phase: NA • Sponsor: State University of New York at Buffalo • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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New app aims to boost college success for veterans with mental health struggles
Knowledge-focused CompletedThis study created and tested a mobile app called VetEd for student veterans dealing with mental health issues like depression, PTSD, or anxiety. The goal was to help them manage academics, mental health, and find resources. Researchers worked with 13 veterans to see if the app w…
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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Hidden ADHD: study reveals how many adults are undiagnosed
Knowledge-focused CompletedThis completed study looked at 224 adults who already had at least one psychiatric condition to see how many also had undiagnosed ADHD. Researchers measured how often ADHD was missed and tracked quality of life in those diagnosed. The goal is to highlight the need for better dete…
Sponsor: Takeda • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC