Acute pyelonephritis
MONDO:0003529Sudden onset pyelonephritis.
Also known as: pyelonephritis, acute
17 clinical trials for this condition and its sub-types.
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Letting patients decide when to stop antibiotics: a pilot study
Disease control CompletedThis pilot study tested whether women with kidney infections could safely stop antibiotics once their symptoms resolved, instead of taking a full 10-day course. 35 women were randomly assigned to either standard treatment or a patient-directed approach. The main goal was to see i…
Phase: PHASE4 • Sponsor: Brett A Faine • Aim: Disease control
Last updated Aug 05, 2026 00:00 UTC
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Can a week of antibiotics beat a kidney infection?
Disease control CompletedThis trial tests whether a 7-day antibiotic course—starting with an intravenous dose of ceftriaxone followed by oral cefixime—can effectively treat acute uncomplicated pyelonephritis (a kidney infection) in women aged 18 to 65. The goal is to see if this shorter regimen works as …
Phase: PHASE4 • Sponsor: University Hospital, Clermont-Ferrand • Aim: Disease control
Last updated Aug 05, 2026 00:00 UTC
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New antibiotic combo shows promise against tough UTIs
Disease control CompletedThis study tested a new antibiotic combination, cefepime-zidebactam, against a standard antibiotic (meropenem) in adults hospitalized with complicated urinary tract infections or kidney infections. About 530 participants received either the new drug or the standard one for 7 to 1…
Phase: PHASE3 • Sponsor: Wockhardt • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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New antibiotic cocktail takes on superbugs in phase 3 trial
Disease control CompletedThis study tested two new antibiotic combinations (cefepime/nacubactam and aztreonam/nacubactam) against the best available treatments for adults with serious infections like urinary tract infections, pneumonia, and abdominal infections caused by carbapenem-resistant bacteria. Th…
Phase: PHASE3 • Sponsor: Meiji Seika Pharma Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC
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Pill power: oral antibiotic could replace IV for tough UTIs
Disease control CompletedThis study tested an oral antibiotic (tebipenem pivoxil hydrobromide) against a standard IV antibiotic in 1,690 hospitalized adults with complicated urinary tract infections or kidney infections. The goal was to see if the oral pill works as well as the IV treatment in curing the…
Phase: PHASE3 • Sponsor: Spero Therapeutics • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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New antibiotic cocktails take on tough UTIs and kidney infections
Disease control CompletedThis phase 3 trial tested two new antibiotic combinations—cefepime/nacubactam and aztreonam/nacubactam—against a standard antibiotic (imipenem/cilastatin) in 614 adults with complicated urinary tract infections or acute kidney infections. The goal was to see if the new combos are…
Phase: PHASE3 • Sponsor: Meiji Seika Pharma Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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Expert advice slashes unnecessary antibiotic prescriptions in family clinics
Knowledge-focused CompletedThis study tested whether adding infectious disease experts to primary care teams helps reduce unnecessary antibiotic use. Over 1,300 patients from six clinics in Spain took part. Doctors in the expert-advised group could call or meet with specialists to discuss tricky cases. The…
Phase: NA • Sponsor: Institut d'Investigació Biomèdica de Bellvitge • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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What predicts survival in severe kidney infections? new study digs into the data
Knowledge-focused CompletedThis study reviewed 575 adults admitted to intensive care for a severe kidney infection called acute obstructive pyelonephritis. Researchers aimed to identify factors that lead to poor outcomes such as death or lasting kidney damage. The goal is to better understand which patient…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC