Acute pyelonephritis

This study is testing the safety and how the body handles Vaborem, a combination of two antibiotics (meropenem and vaborbactam), in children from birth to under 18 years old who have serious Gram-negative bacterial infections. All 44 participants will receive the drug intravenous…

This study tests whether giving oral antibiotics instead of IV antibiotics is just as safe and effective for patients with common infections like pneumonia, urinary tract infections, and cellulitis. About 4,000 adults in Danish emergency rooms will be randomly assigned to start o…

This study compares two antibiotic treatments for acute kidney infection in children aged 1 month to 3 years. One group gets 3 days of IV antibiotics only, while the other gets 3 days IV followed by 7 days of oral antibiotics. The goal is to see if the shorter course works just a…

This study looks at how doctors can improve antibiotic prescriptions for urinary tract infections (UTIs) after patients leave the emergency department. Researchers will check if adjusting antibiotics based on lab test results reduces the use of strong drugs like fluoroquinolones.…

This study from the University of Zurich is looking at how tiny organisms (microbes) and the immune system interact in the bladder. Researchers will collect samples from 800 adults with various urinary conditions, including infections, bladder pain, and overactive bladder, as wel…

This study is testing a new ultrasound method to look at tiny blood vessels in the kidneys of people with nephritis (kidney inflammation). Researchers will use contrast-enhanced ultrasound and ultrasound localization microscopy to create detailed images of kidney blood flow. The …