New antibiotic combo vaborem tested in kids for tough infections
NCT ID NCT06828848
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing the safety and how the body handles Vaborem, a combination of two antibiotics (meropenem and vaborbactam), in children from birth to under 18 years old who have serious Gram-negative bacterial infections. All 44 participants will receive the drug intravenously every 8 hours for up to 14 days. The goal is to find the right dose and ensure it is safe for children.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Vaborem (meropenem plus vaborbactam)
What this could lead to
If this trial works, it could provide a safe and effective antibiotic option for children with serious bacterial infections that are hard to treat.
What could go wrong
This is a small, early-phase study with only 44 children, so results may not apply to all kids. The drug may cause side effects or not work as well as hoped.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Azienda Ospedaliero-Universitaria di Parma
RECRUITINGParma, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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CHRU de Tours Hôpital Clocheville Clinical Research Site
RECRUITINGTours, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Faculty Hospital Kralovske Vinohrady, Paediatric Clinic
RECRUITINGPrague, Czechia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Fakultni nemocnice Ostrava
RECRUITINGOstrava, Czechia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Giannina Gaslini Institute
RECRUITINGGenoa, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Armand Trousseau Clinical Research Site
RECRUITINGParis, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Clinico Universitario de Santiago de Compostela
RECRUITINGSantiago de Compostela, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Dr Josep Trueta
RECRUITINGGirona, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital General Universitario Gregorio Marañón
RECRUITINGMadrid, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Regional Universitario de Málaga
RECRUITINGMálaga, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Sant Joan de Deu
RECRUITINGBarcelona, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Universitario Puerta del Mar
RECRUITINGCadiz, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hôpital Robert Debré
RECRUITINGParis, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hôpital mère-enfant - CHU de Nantes
RECRUITINGNantes, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Insytut Centrum Zdrowia Matki Polki / Polish Mother´s Memorial Hospital Research Institute (ICZMP)
WITHDRAWNLodz, Poland
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Nice University Hospital (CHU de Nice)
RECRUITINGNice, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Ospedale Pediatrico Bambino Gesù
RECRUITINGRome, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Ospedale Regina Margherita
RECRUITINGTorino, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Ospedale Sant'Orsola
RECRUITINGBologna, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Policlinico di Bari
RECRUITINGBari, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Uniwersyteckie Centrum Kliniczne WUM
RECRUITINGWarsaw, Poland
Contact Email: •••••@•••••
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Wojskowy Instytut Medyczny - Państwowy Instytut Badawczy
RECRUITINGWarsaw, Poland
Contact Phone: •••-•••-•••• Email: •••••@•••••