New antibiotic combo shows promise against tough UTIs
NCT ID NCT04979806
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a new antibiotic combination, cefepime-zidebactam, against a standard antibiotic (meropenem) in adults hospitalized with complicated urinary tract infections or kidney infections. About 530 participants received either the new drug or the standard one for 7 to 10 days. The goal was to see if the new antibiotic works as well and is safe. This is a late-stage trial (Phase 3) that has already been completed.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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ACE Hospital and Research Centre
Pune, Maharashtra, 411004, India
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Aartham Multi Super Speciality Hospital
Ahmedabad, 380006, India
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Accord Hospitals
Pune, Maharashtra, 412105, India
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Acibadem City Clinic University Multiprofile Hospital for Active Treatment Tokuda EAD
Sofia, Bulgaria
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Arke SMO S.A. de C.V.
Veracruz, Mexico
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Centro de Investigacion Clinica de Oaxaca (CICLO)
Oaxaca City, Mexico
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Deyang People's Hospital
Deyang, China
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Fakultna nemocnica Nitra
Nitra, Slovakia
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Fakultna nemocnica s poliklinikou F.D. Roosevelta Banska Bystrica
Banská Bystrica, Slovakia
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Fakultna nemocnica s poliklinikou Zilina
Žilina, Slovakia
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Fudan University Huashan Hospital
Shanghai, 200040, China
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General hospital of the PLA northern theater command
Liaoyang, China
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Hospital Angeles Chihuahua
Chihuahua City, 31238, Mexico
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Hunan Provincial People's Hospital
Changsha, China
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Ida-Viru Central Hospital
Kohtla-Järve, Estonia
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JM Research Cuernavaca
Cuernavaca, 62290, Mexico
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Klaipedos university hospital
Klaipėda, LT-92288, Lithuania
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MHAT Dobrich AD
Dobrich, Bulgaria
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Multiprofile Hospital for Active Teatment (MHAT) and Emergency Medicine - Pirogov
Sofia, Bulgaria
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Multiprofile Hospital for Active Treatment (MHAT) Sveta Anna - Varna
Varna, Bulgaria
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Multiprofile Hospital for Active Treatment (MHAT)- Silistra
Silistra, Bulgaria
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Multiprofile Hospital for Active Treatment - KANEV
Rousse, Bulgaria
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Multiprofile Hospital for Active Treatment - Plovdiv AD, Plovdiv
Plovdiv, Bulgaria
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Nemocnica Poprad, a.s. Urologicke oddeleni
Poprad, Slovakia
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North Estonia Medical Centre Foundation
Tallinn, Estonia
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ORIION Citicare Super Speciality Hospital
Aurangabad, 431005, India
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Pharmacology & Clinical Research
Querétaro, Mexico
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Republican Vilnius University hospital
Vilnius, Lithuania
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S&D Clinical Research, LLC
Fort Myers, Florida, 33919, United States
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SCM Sp. z o.o.
Krakow, 31-559, Poland
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Santos Research Center
Tampa, Florida, 33615, United States
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Shaoxing People's Hospital
Shaoxing, China
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South-Estonian Hospital Ltd.
Võru, Estonia
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Supe Hearth & Diabetes Hospital & Research Centre
Nashik, Maharashtra, 422002, India
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Super Speciality Hospital Government Medical College and Hospital
Aurangabad, Maharashtra, 431004, India
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Tartu University Hospital
Tartu, Estonia
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The Second Affiliated Hospital of Chongqing Medical University
Chongqing, 400010, China
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The Second Xiangya Hospital of Central South University
Changsha, China
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UMHAT Aleksandrovska Sofia - Clinic of Urology, Clinic of Anaesthesiology and Intensive Care, Clinic of Clinical Hematology
Sofia, Bulgaria
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UMHAT Dr. Georgi Stranski
Pleven, Bulgaria
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Unidad de Atención Médica e Investigación en Salud (Unamis)
Yucatán, C.P 97000, Mexico
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Uniwersytecki Szpital Kliniczny nr 1 im. Norberta Barlickiego w Lodzi, Oddzial Nefrologii
Lodz, 90-153, Poland
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Vilnius University Hospital Santaros Klinikos
Vilnius, Lithuania
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Vilnius city clinical hospital
Vilnius, Lithuania
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West China Hospital, Sichuan University
Chengdu, 610041, China
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West Tallinn Central Hospital
Tallinn, Estonia
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Wojskowy Instytut Medyczny - Panstwowy Instytut Badawczy, Klinika Chorob Wewnetrznych, Nefrologii i Dializoterapii
Warsaw, Poland
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Zespol Opieki Zdrowotnej w Boleslawcu
Bolesławiec, Poland