Acute pancreatitis
MONDO:0006515An acute inflammatory process that leads to necrosis of the pancreatic parenchyma. Signs and symptoms include severe abdominal pain, nausea, vomiting, diarrhea, fever, and shock. Causes include alcohol consumption, presence of gallstones, trauma, and drugs.
Also known as: acute pancreatitis (disorder) [ambiguous], pancreatitis, acute
103 clinical trials for this condition and its sub-types.
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Broader categories
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New study pits scope against scalpel for pancreatic cleanout
Disease control TerminatedThis study was designed to compare two ways to treat walled-off necrosis (a pocket of dead tissue) caused by severe pancreatitis. One method uses a scope through the mouth to clean out the pocket, the other uses surgery through the stomach. The goal was to see which approach work…
Phase: NA • Sponsor: Stanford University • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Can a double-dose of quit-smoking meds help pancreatitis patients kick the habit?
Symptom relief TerminatedThis study tests whether increasing the dose of varenicline or adding bupropion helps people with recurrent acute or chronic pancreatitis quit smoking. All 45 participants start with standard varenicline; those still smoking after 6 weeks are randomly assigned to a higher dose, a…
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated Jul 09, 2026 00:00 UTC
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Can a digestive enzyme device help pancreatitis patients tolerate tube feeds?
Symptom relief ENROLLING_BY_INVITATIONThis study tests whether RELiZORB, a cartridge containing fat-digesting enzymes, can help adults with moderate to severe acute pancreatitis tolerate tube feeding better. Fifteen participants in the ICU will receive the device and be monitored for how much nutrition they can take …
Phase: PHASE4 • Sponsor: Northwell Health • Aim: Symptom relief
Last updated Jun 27, 2026 12:33 UTC
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New protocol aims to speed up pancreatitis recovery
Knowledge-focused OngoingThis study looks at whether a standard set of guidelines, called the Methodist Acute Pancreatitis Protocol (MAPP), improves care for people with acute pancreatitis. Researchers will compare outcomes like hospital stay length and discharge status before and after the protocol was …
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:04 UTC
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New MRI study aims to spot pancreas trouble early
Knowledge-focused ENROLLING_BY_INVITATIONThis study is testing whether MRI scans can help predict pancreas health and complications like diabetes in children and young adults aged 5 to 21. Researchers will compare MRI images with standard tests like endoscopic pancreas function tests and blood work. The goal is to see i…
Phase: PHASE4 • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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120,000-Person study hopes to crack the code of chronic illness
Knowledge-focused TerminatedThis observational study plans to enroll 120,000 people with various chronic diseases like pancreatitis, diabetes, and arthritis. Researchers will collect blood samples and health data to study how genetics and lifestyle affect disease progression. The goal is to find common dise…
Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Antibiotic penetration in pancreatic collections under study
Knowledge-focused OngoingThis observational study looks at how well antibiotics given through a vein reach infected fluid collections in the pancreas of people with acute pancreatitis. About 40 adults who are already scheduled for drainage of these collections will provide a small fluid sample and a bloo…
Sponsor: Brno University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC