Abdominal aortic aneurysm
MONDO:0005350Enlargement and ballooning of the vessel that supplies arterial blood to the abdomen, pelvis and legs.
Also known as: aortic aneurysm, familial abdominal 1
117 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
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Can a tailored stent graft tame complex aortic aneurysms?
Disease control TerminatedThis trial is testing a specially modified stent graft—a small mesh tube—to repair complex aortic aneurysms in people who are too high-risk for open surgery. The graft is adjusted by the physician to keep blood flowing to the kidneys and other vital organs during the procedure. T…
Phase: NA • Sponsor: Medstar Health Research Institute • Aim: Disease control
Last updated Aug 13, 2026 00:00 UTC
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Can a new stent keep complex aortic aneurysms safely sealed?
Disease control ENROLLING_BY_INVITATIONThis study looks at how well the iCover stent works when used as a bridging stent during a procedure called fenestrated endovascular aneurysm repair (fEVAR) for complex abdominal aortic aneurysms. The goal is to see if the stent stays open and keeps the aneurysm sealed without co…
Sponsor: iVascular S.L.U. • Aim: Disease control
Last updated Aug 05, 2026 00:00 UTC
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New implant aims to shrink deadly belly aneurysms and prevent rupture
Disease control OngoingThis study tests whether adding a special implant (IMPEDE-FX RapidFill) during standard aneurysm repair helps shrink the aneurysm sac more effectively. About 180 adults with large abdominal aortic aneurysms will receive the implant alongside their usual stent graft. The goal is t…
Phase: NA • Sponsor: Shape Memory Medical, Inc. • Aim: Disease control
Last updated Jul 12, 2026 00:00 UTC
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Real-world check for GORE TAMBE device in tough aortic aneurysms
Disease control OngoingThis study follows 300 people who received the GORE TAMBE device to treat complex aortic aneurysms. The goal is to confirm the device works safely and effectively outside of clinical trials. Researchers will track technical success and patient outcomes over 12 months.
Phase: NA • Sponsor: W.L.Gore & Associates • Aim: Disease control
Last updated Jul 09, 2026 00:00 UTC
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New chimney graft study aims to fix tricky aortic aneurysms without open surgery
Disease control OngoingThis study tests a special chimney graft technique for people with a type of aortic aneurysm that is hard to treat because it is close to the kidneys. The goal is to see if this method is safe and works well in everyday medical practice. About 150 adults will take part, and resea…
Sponsor: Medtronic Cardiovascular • Aim: Disease control
Last updated Jun 27, 2026 13:01 UTC
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New stent graft study aims to improve aneurysm repair outcomes
Disease control OngoingThis study follows 164 people with abdominal aortic aneurysm who receive the Ankura stent graft system, a device placed inside the aorta to reinforce the weakened area. Researchers will track major complications and treatment success over 12 months. The goal is to see how well th…
Sponsor: Lifetech Scientific (Shenzhen) Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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New Stent-Grafts aim to fix dangerous aortic bulges without major surgery
Disease control ENROLLING_BY_INVITATIONThis study looks at how well new, custom-made and off-the-shelf stent-grafts work for repairing complex aortic aneurysms (bulges in the main artery). About 750 people with aneurysms in the abdomen, chest, or arch will be treated using a less invasive procedure through blood vesse…
Phase: NA • Sponsor: Carlos Timaran • Aim: Disease control
Last updated Jun 27, 2026 12:32 UTC
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New Blood-Clot monitor could cut transfusions in heart surgery
Disease control OngoingThis study tests whether a bedside device called Quantra can help doctors decide when to give blood transfusions during complex heart surgery. The device measures how well a patient's blood clots in real time. Researchers hope this will reduce the number of blood products (like r…
Phase: NA • Sponsor: The Cleveland Clinic • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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New stent device aims to fix Hard-to-Treat aortic aneurysms
Disease control OngoingThis study is testing a new device called the ChEVAS System for people with complex abdominal aortic aneurysms (bulges in the main blood vessel near the kidneys). The device is placed inside the blood vessel using a catheter, avoiding open surgery. Only 13 people are enrolled, an…
Phase: NA • Sponsor: Endologix • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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New device aims to tame dangerous aortic bulges
Disease control OngoingThis study tests a new device called the Treovance Stent-Graft to treat abdominal aortic aneurysms (a bulge in the main artery). The device is placed inside the artery to reinforce the weak spot and prevent rupture. About 158 adults aged 18-85 with aneurysms large enough to need …
Phase: NA • Sponsor: Bolton Medical • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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New plug may stop aneurysm leaks after surgery
Disease control OngoingThis study tests whether a special plug can safely fill the leftover space inside an abdominal aortic aneurysm after standard stent repair. The goal is to prevent blood leaks (endoleaks) and help the aneurysm heal. Fifteen adults with large aneurysms will receive the plug during …
Phase: NA • Sponsor: Shape Memory Medical, Inc. • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
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New plug aims to seal aneurysm sac and prevent leaks
Disease control OngoingThis study tests a device called IMPEDE-FX that is used to fill the empty space around a stent graft after standard abdominal aortic aneurysm repair. The goal is to see if it is safe and can prevent blood from leaking into the aneurysm sac. The trial involves 15 adults who are al…
Phase: NA • Sponsor: Shape Memory Medical, Inc. • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
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New device aims to stop aneurysm growth without open surgery
Disease control OngoingThis study tests a new device called the Nectero EAST System in 46 people with abdominal aortic aneurysms (AAA). The goal is to see if it is safe and can stop the aneurysm from growing, reducing the need for major surgery. Participants receive the device through a catheter, and d…
Phase: NA • Sponsor: Nectero Medical, Inc. • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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Aneurysm repair may stiffen arteries — a study asks what that means for the heart
Knowledge-focused ENROLLING_BY_INVITATIONThis study follows 60 people with abdominal aortic aneurysm who are scheduled for endovascular repair (EVAR). Researchers will measure artery stiffness, heart structure and function, and certain blood markers before the procedure and at several points afterward. The goal is to un…
Sponsor: Josip Juraj Strossmayer University of Osijek • Aim: Knowledge-focused
Last updated Aug 07, 2026 00:00 UTC
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3D ultrasound could spot hidden clot risks in aneurysms
Knowledge-focused OngoingThis study explores whether a special 3D ultrasound technique, called vector flow imaging, can predict where blood clots form inside abdominal aortic aneurysms. Researchers will scan 14 people with small aneurysms (under 5.5 cm), half with existing clots and half without. They wi…
Sponsor: St. Olavs Hospital • Aim: Knowledge-focused
Last updated Jul 23, 2026 00:00 UTC
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10-Year look at aneurysm device: will it hold up?
Knowledge-focused OngoingThis study follows 2000 people who received the AFX2 system, a device to repair abdominal aortic aneurysms. Researchers will track complications like rupture, need for further procedures, and death over 5 to 10 years. The goal is to see how well the device performs in real-world …
Sponsor: Endologix • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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Family history may raise risk of deadly aneurysm, swedish study suggests
Knowledge-focused OngoingThis study looks at whether brothers, sisters, and children of people who have had an abdominal aortic aneurysm are more likely to develop one themselves. Researchers will analyze health records from nearly one million people in Sweden. The goal is to better understand how family…
Sponsor: Karolinska University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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New study tracks kidney health after aortic stent surgery
Knowledge-focused ENROLLING_BY_INVITATIONThis study follows 770 people who had aortic aneurysm repair using branched stent grafts. Researchers will check kidney function and other organ health over two years to see how different stent designs affect outcomes. The goal is to learn which approaches work best for preservin…
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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New study aims to personalize monitoring of aortic aneurysms
Knowledge-focused ENROLLING_BY_INVITATIONThis study is collecting data from 400 people with abdominal aortic aneurysms to improve how doctors predict aneurysm growth. The goal is to create more personalized monitoring plans. Participants will have regular check-ups and imaging tests to track changes over time.
Sponsor: Karolinska University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Ultrasound hunt for silent artery bulges in seniors and smokers
Knowledge-focused OngoingThis study uses painless ultrasound scans to check for hidden bulges (aneurysms) in the belly and behind the knee in 507 people at higher risk, including older women who smoke and men over 65. The goal is to learn how common these bulges are and what risk factors are linked to th…
Sponsor: Centre Hospitalier Universitaire Vaudois • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Could low selenium be linked to aortic aneurysm?
Knowledge-focused OngoingThis study looks at whether people with an abdominal aortic aneurysm (a bulge in the main artery in the belly) have lower selenium levels than those without the condition. Researchers will compare 40 participants: half with the aneurysm and half without. The goal is to see if sel…
Sponsor: Comenius University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC