Abdominal aortic aneurysm
MONDO:0005350Enlargement and ballooning of the vessel that supplies arterial blood to the abdomen, pelvis and legs.
Also known as: aortic aneurysm, familial abdominal 1
117 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
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Can a new device prevent aortic aneurysm rupture?
Disease control CompletedThis trial is evaluating a new device called the Bifurcated Multilayer Flow Modulator (BMFM) for treating abdominal aortic aneurysms that involve the iliac arteries. The device is designed to be implanted inside the blood vessel to help stabilize the aneurysm and prevent it from …
Phase: NA • Sponsor: Cardiatis • Aim: Disease control
Last updated Aug 12, 2026 00:00 UTC
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Can a stent-graft keep aortic aneurysms in check for years? a long-term follow-up study aims to find out.
Disease control CompletedThis study collects follow-up data from about 300 people who have already received a stent-graft to repair an abdominal aortic aneurysm (AAA). The goal is to assess how safe, effective, and durable the repair is over time. Participants had an AAA larger than 4 cm or one growing r…
Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Jul 26, 2026 00:00 UTC
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New stent graft aims to fix Hard-to-Reach aneurysms while saving key arteries
Disease control CompletedThis trial tests a special stent graft system designed to repair a complex type of abdominal aortic aneurysm that involves the arteries to the kidneys and gut. The device is placed inside the aorta using a minimally invasive procedure, aiming to seal the aneurysm while keeping bl…
Phase: NA • Sponsor: Hangzhou Endonom Medtech Co., Ltd. • Aim: Disease control
Last updated Jul 01, 2026 00:00 UTC
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New device aims to seal aortic aneurysms without open surgery
Disease control CompletedThis study followed 48 people who received the Nellix system, a device that seals abdominal aortic aneurysms from the inside using stents and polymer-filled bags. Researchers tracked how well the device worked right after the procedure and for up to 5 years. The goal was to see i…
Sponsor: Endologix • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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New device aims to fix dangerous belly aneurysms without major surgery
Disease control CompletedThis study tested a device called the Nellix system to repair a bulging blood vessel (aneurysm) in the belly without open surgery. 98 people with large or growing aneurysms took part. The goal was to see if the device is safe and works well at keeping the aneurysm from bursting o…
Phase: NA • Sponsor: Endologix • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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Holographic navigation could make aortic surgery safer
Disease control CompletedThis early feasibility study tested a 3D holographic guidance system to help surgeons place stent grafts during endovascular aortic repair (EVAR) for abdominal aortic aneurysms. Two patients participated, and the system was used alongside standard X-ray imaging to confirm correct…
Phase: NA • Sponsor: The Cleveland Clinic • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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New anchor device aims to secure aortic aneurysm repairs
Disease control CompletedThis registry tracked over 1,000 patients who received the Heli-FX EndoAnchor device during endovascular repair of aortic aneurysms. The device is designed to help hold the endograft in place and prevent leaks. Patients were followed for up to 5 years to see how safe and effectiv…
Sponsor: Medtronic Cardiovascular • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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New device shows promise for aneurysm repair in pelvic arteries
Disease control CompletedThis study looked at how well a special stent (the Gore IBE device) works in real-world use for people with bulging blood vessels (aneurysms) in the belly or pelvis. Researchers tracked 100 patients who already had the device implanted to check if it stayed open and kept the aneu…
Sponsor: Rijnstate Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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New Stent-Graft shows promise for tough aneurysm cases
Disease control CompletedThis study tested a specially designed stent-graft for people with abdominal aortic aneurysms (a bulging blood vessel in the belly) that have a difficult shape near the kidney arteries. Fifty patients received the custom device to see if it could safely seal the aneurysm and keep…
Sponsor: Azienda Ospedaliero-Universitaria di Modena • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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Safer scans: ultrasound may replace CT for aortic aneurysm monitoring
Diagnosis CompletedThis study tested whether a special ultrasound with contrast dye can be as good as CT scans for checking aortic endoprostheses after abdominal aortic aneurysm repair. Forty patients received both an ultrasound and a CT scan after surgery. The goal was to see if ultrasound could d…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Diagnosis
Last updated Jun 27, 2026 12:00 UTC
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Watching videos before surgery may ease nerves, study finds
Symptom relief CompletedThis study tested whether giving vascular surgery patients access to a website with educational videos could reduce their anxiety before the operation. 250 patients were split into two groups: one got the videos, the other did not. Researchers measured anxiety using a simple 0-to…
Phase: NA • Sponsor: Centre Chirurgical Marie Lannelongue • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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Aneurysm repair Follow-Up: which scan is best?
Knowledge-focused CompletedThis study looked at 405 patients who had a minimally invasive procedure to fix an abdominal aortic aneurysm. Researchers reviewed medical records to see how often complications occurred and which imaging test—ultrasound or CT scan—was better at finding them. The goal was to impr…
Sponsor: University Hospital of Limerick • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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300-Patient registry tracks nellix® aneurysm sealer in Real-World use
Knowledge-focused CompletedThis completed registry followed 300 patients with abdominal aortic aneurysm who were treated with the Nellix® Endovascular Sealing System across 30 international centers. The goal was to see how well the device performs in everyday medical practice, measuring safety and effectiv…
Sponsor: Endologix • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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New 3D imaging could cut radiation and repeat surgeries for aneurysm patients
Knowledge-focused CompletedThis study tested whether a special 3D X-ray done in the operating room can replace standard CT scans after repairing an abdominal aortic aneurysm. 427 patients were randomly assigned to either the new 3D scan or the usual approach. The goal was to see if the new method reduces r…
Phase: NA • Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Heart surgery study seeks to pinpoint protection window
Knowledge-focused CompletedThis study looked at 80 adults having heart valve or aortic surgery to find out how long a special heart protection solution (Del Nido cardioplegia) keeps the heart safe during surgery. Researchers took blood samples at set times to see when heart injury began. The goal was to le…
Sponsor: Muhammet Talha Ceran, MD • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Low blood pressure after AAA surgery: hidden risks revealed
Knowledge-focused CompletedThis study looked at 511 patients who had surgery to repair an abdominal aortic aneurysm (a bulging blood vessel in the belly) to find out what makes some people develop dangerously low blood pressure after the operation. The researchers reviewed medical records from 2013 to 2021…
Sponsor: Rijnstate Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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Can ultrasound replace CT scans for aneurysm patients?
Knowledge-focused CompletedThis study looked at 659 patients who had surgery to fix an abdominal aortic aneurysm. Researchers compared two types of scans—CT and ultrasound—to see which one is better at finding problems like leaks or blockages after the repair. The goal was to find out if ultrasound could b…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Big data project aims to boost AAA surgery safety
Knowledge-focused CompletedThis study created a large registry of 394 patients who had surgery for an abdominal aortic aneurysm (AAA) in North Texas hospitals. The goal was to track survival, need for repeat surgery, and risk of rupture over time. By collecting this data, doctors hope to improve the qualit…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Mesh fails to prevent hernias in aortic repair patients
Knowledge-focused CompletedThis study looked at whether placing a mesh during abdominal aortic aneurysm repair could prevent incisional hernias later. Fifty patients were split into two groups: one got mesh reinforcement, the other standard closure. After follow-up, the mesh did not show a clear benefit in…
Sponsor: Hospital Universitario Ramon y Cajal • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Stent graft shows promise for tricky aortic aneurysms
Knowledge-focused CompletedThis study looked back at 268 people who had a wide-neck abdominal aortic aneurysm repaired with the Endurant stent graft. Researchers checked how many needed additional procedures within one year and up to ten years after surgery. They also tracked any leaks around the graft. Th…
Sponsor: Rijnstate Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Aging proteins in artery walls could be key to aneurysm mystery
Knowledge-focused CompletedThis study looked at whether natural aging of proteins in blood vessel walls contributes to the development of aortic aneurysms. Researchers measured skin autofluorescence and collected blood and skin samples from 24 patients undergoing surgery for abdominal aortic aneurysms. The…
Phase: NA • Sponsor: CHU de Reims • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Camera and CT scans could help predict surgical risk in aortic surgery
Knowledge-focused CompletedThis study involved 30 adults undergoing open surgery on the abdominal aorta. Researchers used cameras and CT scans to measure the working space inside the body during surgery. The goal was to create a mathematical model that links a patient's body shape and incision size to the …
Sponsor: Geprovas • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC