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127005 trials found · Page 5409 of 6351
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New study aims to boost cancer screening among american indians
Knowledge-focused CompletedThere are continued disparities in cancer incidence, mortality, and survival between American Indians (AIs) and Whites on cancers responsive to early screening (i.e., breast, colorectal, and cervical) in the US. In New Mexico (NM), AIs compared with other racial/ethnic population…
Sponsor: New Mexico Cancer Research Alliance • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Scientists scan brains to see how magic mushrooms work
Knowledge-focused CompletedThis project will employ functional brain imaging to study the mechanism and immediate and long-term effects of psilocybin, a serotonin receptor 2A agonist, on cortical and cortico-subcortical brain networks in healthy adults.
Early phase 1 • Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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Teacher coaching program aims to curb classroom bullying
Knowledge-focused CompletedThe investigators' overall objective is to demonstrate the efficacy of the Bullying Classroom Check-Up (BCCU) on elementary aged students' aggressive and bullying behaviors, teacher practices, and student and teacher relationships. The investigators' principal hypothesis is that …
Sponsor: Johns Hopkins Bloomberg School of Public Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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New Light-Based technique reveals corneal strength in real time
Knowledge-focused By invitation onlyThe objective of this study is to measure the Brillouin biomechanical properties in keratoconic corneas and characterize biomechanical alterations that occur after corneal procedures that inherently strengthen or weaken the cornea by evaluating the change in Brillouin metrics bef…
Sponsor: The Cleveland Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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Could Low-Nicotine smokes plus E-Cigs cut harm for mentally ill smokers?
Knowledge-focused CompletedThis study aims to determine the health effects of very low nicotine content in cigarettes, in conjunction with the availability of nicotine-containing electronic cigarettes (e-cigs) among smokers with mental health conditions (SMHC).
Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:59 UTC
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Massive ALS biobank aims to unlock secrets of the disease
Knowledge-focused Recruiting nowThe goal of the study is to generate a biorepository of longitudinal biofluids-blood (plasma and serum), cerebral spinal fluid (CSF) and urine linked to genetics and longitudinal clinical information that are made available to the research community. To accomplish these goals, we…
Sponsor: Target ALS Foundation, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Herbal combo shows promise for diabetes control in small study
Disease control CompletedType 2 Diabetes Mellitus (T2DM) is a chronic metabolic disorder characterized by persistent hyperglycemia, which contributes to the formation of advanced glycation end-products (AGEs) and increases the risk of long-term complications. Bitter melon (Momordica charantia L.) contain…
Sponsor: Universitas Muhammadiyah Surakarta • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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Shocking strength: EMS workout tested on couch potato women
Knowledge-focused CompletedAbstract Aim of the Study: This study aimed to compare the effects of Electro Muscle Stimulation (EMS) exercise on physical performance in sedentary women. Methods: Our study was conducted with a total of 27 sedentary women, 12 EMS, and 15 controls, aged 19-24 years. The tests a…
Sponsor: Ondokuz Mayıs University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Zambia study aims to improve HIV care delivery
Knowledge-focused OngoingTo achieve global goals for the treatment of HIV, many countries are piloting and scaling up differentiated service delivery models (DSD). A handful of efforts have been formally described and evaluated in the literature; many others are being implemented formally or informally u…
Sponsor: Boston University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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Worms and COVID: surprising immune link explored in india
Knowledge-focused OngoingThis is a pilot, cross-sectional, sample collection study to characterize the immune response and intestinal microorganisms in people with and without COVID-19 antibodies and helminth infection.
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Smart insoles could forecast knee surgery success
Knowledge-focused Recruiting nowThis multicenter prospective observational study aims to evaluate whether preoperative clinical variables and wearable sensor-derived gait features can predict postoperative improvement after total knee arthroplasty (TKA). Participants will undergo standardized gait assessments u…
Sponsor: Yonsei University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:14 UTC
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Why COVID-19 survivors struggle to breathe: muscle damage revealed
Knowledge-focused CompletedFatigue and exercise intolerance after survived COVID-19-infection might be related to weakness of the respiratory muscles especially following invasive mechanical ventilation in the Intensive Care Unit. The aim of the project is to measure respiratory muscle function and streng…
Sponsor: RWTH Aachen University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Hepatitis b drug holiday: can stopping treatment lead to a cure?
Knowledge-focused OngoingChronic hepatitis B (CHB) infection affected 292 million individuals in the world, translating to about 3.9% of global prevalence. Up to 40% of patients with CHB will develop liver-related complications. Many patients require long-term oral antiviral therapy since off-treatment s…
Sponsor: The University of Hong Kong • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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New study tests earlier treatment for low blood sugar in type 1 diabetes
Knowledge-focused CompletedAccording to guidelines, when a mild-to-moderate hypoglycemia occurs (capillary blood glucose \< 4.0 mmol/L), 15-20g of rapidly absorbed carbohydrates should be ingested. Patients should re-test and re-ingest 15-20g carbohydrates every 15 minutes until they recover from hypoglyce…
Sponsor: Institut de Recherches Cliniques de Montreal • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:11 UTC
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Spinal deformity study seeks to unlock best value care
Knowledge-focused OngoingThe study will examine if variability in created value (outcome/costs) over the care cycle for ASD patients can be explained by patient and treatment characteristics.
Sponsor: Universitaire Ziekenhuizen KU Leuven • Aim: Knowledge-focused
Last updated Jul 12, 2026 00:00 UTC
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Can a special MRI scan predict who will have another stroke?
Knowledge-focused CompletedIntracranial atherosclerotic disease (ICAD) is one of the most important causes of ischemic stroke and is also associated with some recurrent stroke. Safety and effective treatment of ICAD is an important precondition to improve the prognosis of patients. The current therapy for …
Sponsor: Shanghai East Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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AI teaches doctors to see inside the body
Knowledge-focused By invitation onlyPoint-of care-ultrasonography has the potential to transform healthcare delivery through its diagnostic and therapeutic utility. Its use has become more widespread across a variety of clinical settings as more investigations have demonstrated its impact on patient care. This incl…
Sponsor: Stanford University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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Too much oxygen in ICU linked to higher death risk
Knowledge-focused CompletedIn our study, to research the prevalence of hyperoxemia in adult patients treated in the intensive care unit (ICU) and its relationship with clinical outcomes. This single-center, observational study included 260 consecutive patients aged 18-85 years who received oxygen therapy i…
Sponsor: Trakya University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Gentle tai chi may help older hearts and minds, small study suggests
Disease control CompletedHigh blood pressure and poor cognitive function are two common health problems among older adults in the United States. They are also closely related because high blood pressure may lead to negative changes in brain structure and function such as poor brain blood flow that can ca…
Sponsor: University of Connecticut • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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Scientists probe cellular signals that may trigger early labor
Knowledge-focused CompletedThis completed observational study evaluated the expression of Hippo-YAP pathway-related genes and proteins and selected microRNAs in maternal blood, placental tissue, and myometrial tissue obtained from women who underwent cesarean delivery at term or preterm gestational ages. …
Sponsor: Cumhuriyet University • Aim: Knowledge-focused
Last updated Jul 12, 2026 00:00 UTC