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127426 trials found · Page 5258 of 6372
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New online training aims to help mental health providers reach underserved youth
Knowledge-focused CompletedThe overall goal of the larger 3-aim study is to develop and pilot test a training intervention to increase mental health providers' use of evidence-based practices with youth patients. Aim 3 (registered here) of the study is an open trial pilot study at a multi-clinic mental hea…
Sponsor: Boston College • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Can bringing family into therapy boost anxiety treatment for veterans?
Symptom relief CompletedDespite the prevalence of posttraumatic stress disorder and anxiety disorders among Veterans, there has been limited focus on the development of interventions that include family members in treatments provided to Veterans. This is a feasibility study that examines a novel adjunct…
Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Jun 26, 2026 14:22 UTC
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Diabetes and fatigue: can special exercise training help?
Knowledge-focused Recruiting nowPre-diabetes (Pre-D) is a precursor to type 2 diabetes (T2D) and characterized by increased exercise fatigability of lower limb muscles, that can impede exercise performance. The cause for the increased fatigability in people with Pre-D is not known. Given the profound vascular d…
Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Sep 03, 2026 00:00 UTC
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Brain scans reveal how learning rewires Stroke-Damaged brains
Knowledge-focused CompletedAfter a stroke, plasticity occurs in the brain from microscopic to network level with positive but also negative consequences for functional recovery. Why post-stroke plasticity takes a beneficial or a maladaptive direction is still incompletely understood. Because the biological…
Sponsor: Medical University of South Carolina • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC
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Nursing home drug trends: are dementia patients getting unmonitored meds?
Knowledge-focused By invitation onlySince the "National Partnership to Improve Dementia Care" debuted in 2012, almost all long-stay psychoactive prescribing has been graded by CMS, which has correlated to decreased use. However, some national data suggest that while these psychoactive medications are being used les…
Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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Nerve block may unlock secrets of dangerous heart rhythm
Knowledge-focused Recruiting nowProspective cohort study evaluating the electrophysiologic and biochemical effects of stellate ganglion block in patients with ventricular tachycardia.
Early phase 1 • Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Olive oil and prebiotics: a tasty way to fight muscle loss in seniors?
Symptom relief CompletedThe main objective of the present study is to add knowledge of the potential health effects and mechanism of action by a dietary strategy based on a VOO rich in phenolic compounds (156 mg hydroxytyrosol and tyrosol/kg oil) alone or combination with prebiotic supplementation based…
Sponsor: University Rovira i Virgili • Aim: Symptom relief
Last updated Jun 27, 2026 08:06 UTC
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Trauma's hidden toll: new study probes blood changes that raise infection risk
Knowledge-focused Recruiting nowThe goal of this observational study is to better understand what happens to circulating blood after a patient experiences severe trauma injury. The main questions it aims to answer are: Is severe human trauma associated with specific patterns of development in the hematopoietic …
Sponsor: University of Florida • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Which heparin method works best during heart ablation?
Knowledge-focused OngoingThromboembolism and bleeding are still the most common encountered complications during atrial fibrillation ablation. The purpose of this study is to investigate a prespecified protocol-driven continuous heparin infusion method comparing intermittent bolus method for an optimal a…
Sponsor: National Taiwan University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Knee surgery showdown: which cut spares your blood vessels?
Knowledge-focused CompletedThe Aim Is To Study The Anatomic Relationship Of The Popliteal Vesseles In Two Types Of (OWHTO) Techniques (Monoplanar VS Biplanar) Which Provide More Safe Technique To The PV
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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Heart failure clue found in coronary sinus blood
Knowledge-focused OngoingHeart failure (HF) is one of the clinical syndromes with the highest morbidity and mortality rates among cardiovascular diseases. Despite pharmacological treatments, symptoms persist in a significant proportion of patients, and mortality cannot be prevented. Therefore, device-bas…
Sponsor: Trakya University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Practice makes perfect: simulation training eases anxiety for student midwives
Knowledge-focused CompletedThis randomized controlled quasi-experimental study investigated the effects of simulation-based vaginal examination training on skill performance, anxiety, and satisfaction in third-year midwifery students at a state university in Turkey. A total of 67 students participated (32 …
Sponsor: Ondokuz Mayıs University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:09 UTC
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New imaging study aims to uncover hidden inflammation in genetic heart disease
Knowledge-focused Recruiting nowStatus of the research project: The main complications of arrhythmogenic cardiomyopathies (AC) are sudden death, more rarely heart failure. Recently, data are emerging in favor of an associated role of myocardial inflammation and myocarditis in this pathology, but the impact of i…
Sponsor: Nantes University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:09 UTC
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HIV drug comparison study seeks clues to shrink hidden virus
Knowledge-focused By invitation onlyThe goal of the project is to determine the difference in immune activation and HIV reservoir size between People living with HIV (PWH) on tenofovir-containing antiretroviral therapy (ART) versus PWH on nucleoside reverse transcriptase inhibitor (NRTI)-sparing ART. Tenofovir (TFV…
Sponsor: University of Washington • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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Could a special MRI replace dental X-Rays for jaw and tooth issues?
Diagnosis Recruiting nowThe aim of the present study is to show that the use of 0.55T MRI combined with a "dental" coil produces images of sufficient diagnostic value to assess areas of interest in dentistry, and to compare MR images to traditional, dental-oriented radiographic images for diagnostic pur…
Sponsor: University of Aarhus • Aim: Diagnosis
Last updated Jun 27, 2026 12:29 UTC
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New laser may speed up kidney stone removal
Symptom relief CompletedTo compare intraoperative as well as postoperative outcomes of SOLTIVE Thulium laser compared to Ho:YAG laser for the treatment of urolithiasis. The hypothesis is that utilizing the SOLTIVE Thulium laser for the treatment of urolithiasis will result in a more efficient procedure…
Sponsor: University of Kansas Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 12:30 UTC
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Which drug keeps sinus surgery cleaner? dexmedetomidine vs. nitroglycerin
Symptom relief CompletedSinus surgery is one of the most prevalent ear, nose, and throat (ENT) surgeries, which is mainly carried out nowadays through functional endoscopic sinus surgery (FESS) and leads to significant improvement in the clinical symptoms of patients with rhinosinusitis. It is necessary…
Sponsor: Zagazig University • Aim: Symptom relief
Last updated Jun 27, 2026 12:34 UTC
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Show and tell: simple trick slashes Kids' dental needle fear
Symptom relief CompletedDental anxiety is common in children and may increase during local anesthesia administration. Dental injection anxiety is one of the most frequently reported causes of dental anxiety in pediatric dental patients. Communication-based behavior guidance techniques are commonly used …
Sponsor: Bezmialem Vakif University • Aim: Symptom relief
Last updated Jun 27, 2026 13:03 UTC
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Rare lung vein condition targeted by novel transplant trial
Disease control CancelledThis is a prospective, single center, safety and feasibility trial to evaluate the transplantation of the left atrium and pulmonary veins in patients with pulmonary vein stenosis. Consented patients will be listed for transplantation. Once a suitable donor has been identified, th…
Sponsor: Boston Children's Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:38 UTC
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Could a 10-Minute AR lesson save lives in a hospital fire?
Knowledge-focused CompletedThis study evaluated the effectiveness of augmented reality-based hospital fire-safety education among hospitalized patients and accompanying caregivers. Hospital fires pose substantial risks to patient safety because of complex clinical environments, high reliance on electrical …
Sponsor: Chou Yun Jyuan • Aim: Knowledge-focused
Last updated Jul 31, 2026 00:00 UTC