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116076 trials found · Page 4321 of 5804
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Mind-Reading wearables? USC tests sensors that track emotions
Knowledge-focused Recruiting nowIn this program, the investigators will develop novel multimodal neural-behavioral-physiological monitoring tools (software and hardware), and machine learning models for mental states within social processes and beyond. The tools consist of a multimodal skin-like wearable sensor…
Phase: NA • Sponsor: University of Southern California • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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Which mesh wins? new study tests infection risk in hernia surgery
Knowledge-focused CompletedThis study compares the incidence of surgical site infections (SSI) in patients undergoing abdominal hernia repair using either light or heavy-weighted polypropylene mesh. The study aims to determine which mesh type results in fewer SSIs, thereby guiding future surgical approache…
Phase: NA • Sponsor: Khyber Medical University Peshawar • Aim: Knowledge-focused
Last updated Jun 26, 2026 12:36 UTC
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Exercise may alter Depression-Related brain chemicals, small trial hints
Knowledge-focused Recruiting nowThis study aims to investigate changes in the levels of biomarkers (IGF-1, FGF2, and EGF) involved in neuron development in patients diagnosed with major depression through the effects of breathing exercises and aerobic exercise, as well as to examine the levels of biomarkers (TN…
Phase: NA • Sponsor: Kutahya Health Sciences University • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:28 UTC
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Sonic zap eases kids' tooth pain, AI reads their faces
Symptom relief CompletedThis study was conducted to evaluate the efficiency of sonic activation of 5%sodium hypochlorite during root canal treatment of primary molars on postoperative pain and facial expressions. In addition to comparing between the Five-face pain scale and AI Emotion Detector mobile ap…
Phase: NA • Sponsor: Suez Canal University • Aim: Symptom relief
Last updated Jun 26, 2026 15:31 UTC
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Could home palliative care keep kids out of the hospital?
Knowledge-focused ENROLLING_BY_INVITATIONThe purpose of this study is to test the hypothesis that the addition of home-based hospice and palliative care (HBHPC) will provide a reduction in health care utilization, improve quality of life, and facilitate goal-concordant care that is superior to inpatient and clinic pedia…
Sponsor: Steven Smith • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC
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Birth control pills may tighten knees, new study suggests
Knowledge-focused Recruiting nowWomen are recognized as being at greater risk of ACL injury, with a risk 6 times higher than that of men. Hyperlaxity is a risk factor for ACL injury, but the pathophysiological basis for this is poorly studied. Hormonal impregnation and certain periods of the menstrual cycle (ov…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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Could a lidocaine combo ease pain after fibroid surgery?
Symptom relief Recruiting nowThe purpose of this study is to determine whether laparoscopic spraying combined with intravenous injection of lidocaine can improve pain in patients undergoing laparoscopic myomectomy under general anesthesia.
Phase: NA • Sponsor: General Hospital of Ningxia Medical University • Aim: Symptom relief
Last updated Jun 27, 2026 08:02 UTC
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New pain combo eases liver cancer procedure recovery
Symptom relief CompletedTo evaluate the effectiveness of the combination of hydrochloride hydromorphone and flurbiprofen ester for post-TACE intravenous patient-controlled intravenous analgesia (PCIA).
Phase: PHASE4 • Sponsor: First Affiliated Hospital, Sun Yat-Sen University • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
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Gel from joint treatments may speed wisdom tooth healing
Symptom relief Recruiting nowComplications such as postoperative pain and delayed socket healing are relatively common following surgical extraction of mandibular third molars. Various biomaterials have been investigated to enhance wound healing and reduce postoperative morbidity. Hyaluronic acid (HA) has de…
Phase: NA • Sponsor: Jordan University of Science and Technology • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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Acupuncture needles take aim at eye strain
Symptom relief CompletedThe study is designed to assess the effiacy of acupuncutre on eye fatigue. The indicator of eye fatigue is eye accommodation ability. Patients will be randomly assigned to the experimental group and the control group. The experimental group will receive acupuncture treatment, whi…
Phase: NA • Sponsor: Chung Shan Medical University • Aim: Symptom relief
Last updated Jun 27, 2026 08:05 UTC
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Jaw pain relief study finds best washing method
Symptom relief CompletedTemporomandibular disorders (TMD) are common conditions in society, characterised by symptoms such as pain, limited movement and joint noises, which negatively affect an individual's quality of life. The primary goal of treatment is to restore the physiological functions of the j…
Phase: NA • Sponsor: Helin Merve Özalp • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
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Drum circles and meditation: a new way to beat stress?
Knowledge-focused ENROLLING_BY_INVITATIONMental health vulnerability due to stress is increased in People of African Descent (PADs) in America due to disproportionate effects of racism, poverty, education, and criminal justice sentencing. Various meditation and mindfulness approaches have provided evidence of measured r…
Phase: NA • Sponsor: Yale University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Music and mindfulness: a new way to ease stress in black communities?
Knowledge-focused Recruiting nowMental health vulnerability due to stress is increased in People of African Descent (PADs) in America due to disproportionate effects of racism, poverty, education, and criminal justice sentencing. Various meditation and mindfulness approaches have provided evidence of measured r…
Phase: NA • Sponsor: Yale University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Can free legal services ease the burden of colorectal cancer?
Symptom relief CompletedThis is a single center single-arm, pilot study of proactive and early connection with free legal care services for persons with advanced colorectal cancer to assess the feasibility, acceptability, and preliminary efficacy of this intervention in improving financial and psychosoc…
Phase: EARLY_PHASE1 • Sponsor: University of Minnesota • Aim: Symptom relief
Last updated Jun 27, 2026 09:04 UTC
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Massive asia-wide study aims to save young lives in intensive care
Knowledge-focused Recruiting nowThe overall objective of this study is to improve the standard of care of critically ill pediatric patients. The specific aims are to describe the clinical profile and outcomes of all admissions to Asian pediatric ICUs, determine the risk factors associated with poor outcomes, de…
Sponsor: KK Women's and Children's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Healthy volunteers help scientists map Brain's pain pathways for migraine insights
Knowledge-focused OngoingIn previous studies clustering of the three branches of the trigeminal nerve in brainstem were shown, cerebellum and periaqueductal gray. To further evaluate higher cortical structures, which were not covered by our previous field of view (FOV) and to further investigate the iden…
Phase: NA • Sponsor: Universitätsklinikum Hamburg-Eppendorf • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:34 UTC
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Shockwave showdown: which knee pain therapy wins?
Symptom relief CompletedThe goal of this clinical trial is to evaluate and compare the effectiveness of radial pressure wave therapy (RPWT) applied at different anatomical sites in patients with knee osteoarthritis (OA) over a follow-up of four months. The main questions it aims to answer are: How effe…
Phase: NA • Sponsor: Hospital Civil de Guadalajara • Aim: Symptom relief
Last updated Jun 27, 2026 12:34 UTC
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Weighty issue: does obesity block iron supplements?
Knowledge-focused CompletedThis clinical trial aims to learn if there is a relationship between OWT/OB and IDA in nonpregnant women of reproductive age and its impact on iron supplementation. The main questions it aims to answer are: * Is there any independent association between overweight/obesity and ir…
Phase: NA • Sponsor: Griffith University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
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New PET scan tracer could spot keloids without a biopsy
Diagnosis Recruiting nowKeloids are often described as benign dermal fibroproliferative lesions characterized by increased growth beyond the boundaries of the original wound margin.Fibroblasts are considered to be the key cellular mediators of fibrogenesis in keloid scars. Thus this prospective study is…
Phase: PHASE1, PHASE2 • Sponsor: Peking Union Medical College Hospital • Aim: Diagnosis
Last updated Jun 27, 2026 14:01 UTC
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Laser eye surgery showdown: which fix for nearsightedness is better?
Disease control OngoingFemtoLASIK is a type of laser eye surgery used to correct vision problems such as nearsightedness, farsightedness, and astigmatism. It involves two main steps: creating a flap and reshaping the cornea. Refractive lenticule extraction, (KLEx) is another laser eye surgery method to…
Phase: NA • Sponsor: Instituto de Oftalmología Fundación Conde de Valenciana • Aim: Disease control
Last updated Jun 27, 2026 14:03 UTC