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127005 trials found · Page 3603 of 6351
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Weekly radiation may ease path to CAR t for tough lymphomas
Disease control CompletedParticipants are invited to take part in this research study because they have relapsed (cancer has come back) or refractory (cancer has not responded to treatment) B-cell Lymphoma and will be undergoing CAR T-cell Therapy. This research is being done to see if a new radiation t…
Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Can a new inhaler match Symbicort's performance?
Knowledge-focused CompletedThe goal of this study is to learn if a new formulation of Budesonide/Formoterol Inhalation Powder (160μg/4.5μg), manufactured by Shanghai New Huanghe Pharmaceutical Co., Ltd., works the same as the already approved reference product, Symbicort® Turbuhaler® (160μg/4.5μg), in the …
Phase 1 • Sponsor: Shanghai Xin Huanghe Pharmaceutical Co., Ltd. • Aim: Knowledge-focused
Last updated Sep 06, 2026 00:00 UTC
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New sleep drug for surgery put to the test
Symptom relief CompletedTo demonstrate HSK3486 0.4/0.2 mg/kg (0.4 mg/kg intravenous \[IV\] slow injection over 30 \[±5\] seconds for the first dose, an additional 0.2 mg/kg if needed) is non-inferior to Propofol 2.0/1.0 mg/kg (2.0 mg/kg IV slow injection over 30 \[±5\] seconds for first dose, an additio…
Phase 3 • Sponsor: Haisco-USA Pharmaceuticals, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 07:54 UTC
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Long flights may swell leg veins for days, study asks
Knowledge-focused Recruiting nowThis prospective repeated-measures study will evaluate how long popliteal vein dilation persists after international commercial air travel to Bogota. Adult medical travelers will undergo standardized bilateral popliteal vein ultrasound within 24 hours before departure, within 2 h…
Sponsor: Research Inc • Aim: Knowledge-focused
Last updated Sep 09, 2026 23:00 UTC
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Heart attack survivors get a buddy: new program aims to keep them moving
Knowledge-focused CompletedFollowing myocardial infarction, cardiac rehabilitation has undeniable benefits on criteria such as cardiovascular mortality and coronary recurrence. Cardiac rehabilitation consists of 3 phases: 1. immediate post-acute, in a cardiology department, 2. active cardiac rehabilitatio…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Cranberry juice may boost brainpower during multitasking, study hints
Symptom relief PausedThis clinical trial aims to investigate the effects of a 70-day consumption of cranberry juice on cognitive and motor accuracy, mental and physiological stress, and stress response in healthy men and women between the ages of 30 and 55 who engage in multitasking. The trial will u…
Sponsor: University of Florida • Aim: Symptom relief
Last updated Jul 04, 2026 00:00 UTC
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Zapping acupoints may keep seniors Clear-Headed after surgery
Symptom relief CompletedTranscutaneous electrical acupoint stimulation (TEAS) was reported to benefit the patients undergoing surgeries by reducing anesthetics consumption and decreasing anesthesia related adverse effects. Electroencephalogram (EEG) and EEG-related indicators are important indicators re…
Sponsor: Zhihong LU • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC
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Scientists scan brains to find the off-switch for negative thoughts in depression
Knowledge-focused CompletedThe purpose of this study is to decode different thinking states from the brain activation patterns and identify the neural circuits that disengage from these thinking patterns using functional magnetic resonance imaging (fMRI) measurement in individuals with major depressive dis…
Sponsor: Laureate Institute for Brain Research, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Could the speed of anesthesia gas shape lung recovery after nose surgery?
Knowledge-focused CompletedThis prospective, single-center observational cohort study evaluated the association between fresh gas flow rate during inhalational anesthesia and perioperative changes in lung aeration in adults undergoing elective surgery for nasal septal deviation. Participants were classifi…
Sponsor: Fatih Sultan Mehmet Training and Research Hospital • Aim: Knowledge-focused
Last updated Aug 13, 2026 00:00 UTC
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New score could spare epilepsy patients from invasive brain probes
Knowledge-focused By invitation onlyThe purpose of this study is to assess how well a new scoring system called the 5-SENSE score can predict where seizures start in the brain using Stereoelectroencephalography (SEEG). The 5-SENSE Score is a 5-point score based on routine presurgical work-up, designed to assist in …
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:02 UTC
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Pharmacists take on high blood pressure: home monitoring trial for women
Disease control OngoingTo evaluate the impact of home blood pressure monitoring when used in addition to pharmacist care, compared to usual care, in women with elevated blood pressure (BP). Randomized 1:1 two-arm controlled trial. Patients to be identified and screened by pharmacists. Patients with a B…
Sponsor: University of Alberta • Aim: Disease control
Last updated Aug 20, 2026 00:00 UTC
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Blood test may spot hidden heart valve infections
Knowledge-focused CompletedFew teams in the world can reliably analyze tissue microbiota. In this regard, the present group has unique expertise in the analysis of blood and tissue microbiota, the first to describe in 2011. Having a blood biomarker of this valve microbiota could help guide the therapeutic…
Sponsor: University Hospital, Toulouse • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Could your own blood ease knee arthritis pain?
Symptom relief CompletedThe purpose of this study is to determine the effectiveness and safety of autologous alpha-2 macroglobulin rich plasma (A2MRP) injections in the treatment of knee osteoarthritis (OA).
Phase 1/2 • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC
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Can a less extensive stomach surgery preserve appetite better?
Symptom relief OngoingParticipants will a diagnosis of gastroesophageal junction (GEJ) adenocarcinoma and will have either a minimally invasive proximal gastrectomy (MIPG) or a minimally invasive total gastrectomy (MITG) as part of their routine care. Participants with complete a questionnaire 1 month…
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Symptom relief
Last updated Jul 24, 2026 00:00 UTC
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Yoga from home may boost weight loss, new study hopes
Symptom relief OngoingThe purpose of this study is to examine whether the addition of online yoga classes, compared to health and wellness classes, can improve the amount of weight loss produced from an Internet-based weight loss program. All individuals will receive a 12-month, automated Internet-bas…
Sponsor: The Miriam Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:33 UTC
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Shock waves vs needle lavage: which eases shoulder pain best?
Symptom relief CompletedThe objective of this systematic alternating prospective experimental longitudinal analytical clinical trial is to compare the mean differences in Visual analgesic scale (VAS) at 1 month, 3 months and 6 months depending on the treatment received, ultrasound-guided barbotage (US-P…
Sponsor: Maimónides Biomedical Research Institute of Córdoba • Aim: Symptom relief
Last updated Jul 23, 2026 00:00 UTC
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Can a Vitamin-Like pill boost fat burning on a keto diet?
Knowledge-focused Recruiting nowBackground: At least 30% of Americans have fatty liver disease. This means that they store too much fat in the liver. At the moment lifestyle changes are the only way to treat this problem. Objective: To test how (1) a low-carbohydrate diet and (2) a supplement called nicotina…
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Knowledge-focused
Last updated Sep 06, 2026 00:00 UTC
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Which works better for h. pylori? triple vs quadruple therapy showdown
Disease control CompletedThis randomized controlled trial is designed to compare the efficacy of standard triple therapy versus bismuth-based quadruple therapy for the eradication of Helicobacter pylori-induced gastritis. The study is being conducted at Shahida Islam Medical College, Lodhran, Pakistan. A…
Phase 4 • Sponsor: Azfar Farogh • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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New computer tool aims to help young cancer patients take control of symptoms
Symptom relief Recruiting nowDetermine the effects of the Computerized Symptom Assessment Tool (C-SCAT) versus usual care on the primary outcomes of self-efficacy for symptom management and symptom self-management behaviors
Sponsor: Virginia Commonwealth University • Aim: Symptom relief
Last updated Jun 27, 2026 12:36 UTC
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Veterans with COPD and pain test remote walking and tai chi program
Symptom relief Recruiting nowPersons with COPD benefit from being physically active, but they are often limited by chronic musculoskeletal pain. This project will determine whether a non-pharmacologic, integrated, technology-mediated walking and Tai Chi mindfulness intervention can improve physical function …
Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC