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Long flights may swell leg veins for days, study asks

NCT ID NCT07808411

Knowledge-focused Sponsor: Research Inc Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
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Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
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Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
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Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 08, 2026 · Last updated Sep 09, 2026 · Updated 1 time

Summary

This study tracks leg vein size in adults before and after a commercial flight of at least 4 hours to Bogota. Researchers use ultrasound to measure the popliteal vein in the leg within 24 hours before departure, within 2 hours after arrival, and again at 24 and 48 hours later. The goal is to see how long any flight-related vein dilation lasts and whether it returns to normal before surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Commercial air travel exposure and standardized bilateral popliteal vein duplex ultrasound
What this could lead to
If vein dilation persists beyond 48 hours, it could inform guidelines on when it is safe to undergo surgery after long flights.
What could go wrong
This is an observational study with a small sample, and results may not apply to all travelers. It does not test any treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2024

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult international medical travelers completing a commercial flight of at least 4 hours to Bogota and undergoing all ultrasound measurements before surgery.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18 to 65 years. * International commercial flight to Bogota with total airborne time of at least 4 hours. * Preflight baseline ultrasound obtained within 24 hours before departure using the standardized protocol. * Arrival ultrasound completed within 2 hours after reaching the study site and before surgery or intravenous fluid therapy. * Availability for 24-hour and 48-hour examinations. * Written informed consent. Exclusion Criteria: * Known current deep venous thrombosis or pulmonary embolism. * Therapeutic anticoagulation at enrollment. * Major lower-extremity venous surgery, active leg infection, or condition preventing popliteal ultrasound. * Surgery, prolonged immobilization, or substantial intravenous fluid administration before completion of the 48-hour measurement. * Pregnancy. * Nondiagnostic baseline examination or inability to reproduce the landmark.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Air travel Physiologic venous dilation

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

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Contacts and locations

Locations

  • Clinica INO

    RECRUITING

    Bogotá, Colombia

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