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116076 trials found · Page 3192 of 5804
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Acupuncture vs. placebo: can Needle-Free technique flip breech babies?
Disease control CompletedFor breech presentation, the cesarean section rate is decreased by external cephalic version. This is a painful operation, with some rare but serious complications. The aim of this trial is to evaluate the effectiveness of acupuncture-moxibustion, a non-invasive technique, to cor…
Phase: NA • Sponsor: University Hospital, Lille • Aim: Disease control
Last updated Jun 27, 2026 08:00 UTC
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Blue dye and radioactive tracer team up to spot cancer spread
Knowledge-focused CompletedThe aim of this study is to evaluate the performance of a double labelling method using isotope and methylene blue dye injection to localize precisely Sentinel Lymph Node (SLN) in a series of 100 patients with infiltrative breast cancer justifying SLN excision. Method and patient…
Phase: NA • Sponsor: University Hospital, Strasbourg, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Could a simple biopsy replace major surgery for multifocal breast cancer?
Knowledge-focused CompletedThe scope of this trial is to assess the Sentinel Lymph Node Technique in Multifocal Breast Cancer
Phase: PHASE2 • Sponsor: Centre Oscar Lambret • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Tailored workouts may boost heart function in obesity and diabetes
Knowledge-focused CompletedObesity and diabetes increase cardiovascular risk by complex and incompletely known mechanisms. The aims of this study are : 1. to compare cardiac and vascular functions at rest and during exercise in 4 groups of age-matched men, without cardiovascular diseases but exhibiting in…
Phase: PHASE4 • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Experimental drug targets rare eye cancer in small trial
Disease control CompletedTo evaluate objective response rate and duration of response to weekly Taxoprexin®. To evaluate the safety profile of weekly Taxoprexin® in this patient population. To evaluate overall survival in the same patient population. To evaluate time to disease progression, and the tim…
Phase: PHASE2 • Sponsor: American Regent, Inc. • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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Which statin works best for HIV patients with high cholesterol?
Disease control CompletedIn HIV hypercholesterolemic patients treated with protease inhibitors, some drugs of the statin group are used to control cholesterol level. New and potentially more efficient statins may interfere with protease inhibitors and hence loose a part of their activity. They have thus …
Phase: PHASE4 • Sponsor: French National Agency for Research on AIDS and Viral Hepatitis • Aim: Disease control
Last updated Jun 27, 2026 12:03 UTC
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Scientists hunt for genetic clues to breast cancer recurrence
Knowledge-focused Recruiting nowThe main purpose of this study is to compare genetic markers present on tumor cells before and after chemotherapy.
Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Soy food may lower heart attack risk in women, large study suggests
Prevention CompletedTo investigate whether soy food intake reduces risk of non-fatal myocardial infarction (MI) and fatal coronary heart disease in Chinese women.
Sponsor: Vanderbilt University Medical Center • Aim: Prevention
Last updated Jun 27, 2026 13:00 UTC
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Scientists hunt for heart rhythm genes in 1,300 patients
Knowledge-focused OngoingThe purpose of this study is to establish a genebank repository of blood samples and data to generate information about the hereditary (genetic) basis of atrial fibrillation.
Sponsor: The Cleveland Clinic • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:45 UTC
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Mini GPS in a needle could help doctors hit hidden tumors
Knowledge-focused ENROLLING_BY_INVITATIONThis study will evaluate the accuracy and effectiveness of an experimental tracking device for locating abnormalities during invasive procedures, such as biopsy or ablation, that cannot easily be visualized by usual imaging techniques, such as computed tomography (CT) scans or ul…
Phase: NA • Sponsor: National Institutes of Health Clinical Center (CC) • Aim: Knowledge-focused
Last updated Jul 26, 2026 00:00 UTC
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Could better hospital food save lives and money?
Knowledge-focused Recruiting now1. The aim of this large scale study to survey the prevalence of nutritional risk and malnutrition in China,Europe and USA. 2. The impact of nutritional support for the patients at nutritional risk on clinical outcomes and cost-effectiveness Already get the approval by Ethics Co…
Sponsor: Peking Union Medical College • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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Asthma drug roflumilast tested for Long-Term safety in new study
Disease control CompletedThe aim of this long-term study is to investigate the effect of roflumilast (APTA-2217) on the long-term safety in patients with asthma, who completed the 24-week evaluation of study APTA-2217-05. Roflumilast will be administered orally once daily. The present study consists of a…
Phase: PHASE3 • Sponsor: AstraZeneca • Aim: Disease control
Last updated Jun 27, 2026 13:07 UTC
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Massive study tracks hidden liver dangers of common drugs and herbal remedies
Knowledge-focused Recruiting nowThe purpose of this study is to identify individuals who have suffered a liver injury arising as an idiosyncratic reaction to a prescription drug or a complementary and alternative medicine. Recently added acute cases enrollment that meets criteria to the protocol. Also added Fib…
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Scientists probe why endometriosis pain persists
Knowledge-focused CompletedThis study will examine pelvic pain associated with endometriosis and explore better approaches to treatment. In women with endometriosis, uterine tissue grows outside the uterus. Standard treatments - altering hormone levels to prevent endometrial tissue growth or surgically rem…
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS) • Aim: Knowledge-focused
Last updated Jul 18, 2026 00:00 UTC
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New database aims to unlock secrets of childhood liver disease
Knowledge-focused Recruiting nowBiliary atresia, idiopathic neonatal hepatitis, and specific genetic cholestatic conditions are the most common causes of jaundice and hyperbilirubinemia that continue beyond the newborn period. The long term goal of the Childhood Liver Disease Research Network (ChiLDReN) is to e…
Sponsor: Arbor Research Collaborative for Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:03 UTC
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Can your genes raise your risk for blood cancer? a new study aims to find out
Knowledge-focused Recruiting nowBlood and lymph node cancers can begin in either the lymphatic tissues (as in the case of lymphoma) or in the bone marrow (as with leukemia and myeloma), and they all are involved with the uncontrolled growth of white blood cells. There are many subtypes of these cancers, e.g., c…
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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Can heart checks save Hodgkin's survivors?
Knowledge-focused OngoingThe main purpose of this study is to determine if it is possible to put into practice a cardiac screening program for survivors of Hodgkin's disease. In this study, we would also like to screen for cardiac risk factors that can be modified either through life-style changes or med…
Phase: NA • Sponsor: Dana-Farber Cancer Institute • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:30 UTC
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Can IL-2 keep HIV patients healthier without antiretrovirals?
Disease control CompletedInterleukin-2 (IL-2) increases the number of CD4 cells in HIV-1 infected patients under highly active antiretroviral therapy (HAART) with a CD4 cell count over 200/mm3, but its activity in patients without antiretroviral therapy is unknown. This study will test the efficacy and s…
Phase: PHASE2 • Sponsor: French National Agency for Research on AIDS and Viral Hepatitis • Aim: Disease control
Last updated Jun 27, 2026 12:03 UTC
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Massive heart database aims to unlock secrets of cardiovascular disease
Knowledge-focused Recruiting nowIn the present study, investigators intend to establish a large database of cardiovascular patients. More specifically, investigators will create a database of approximately 12,000 cardiac catheterization and heart failure patients from Emory University Hospital, the Emory Clinic…
Sponsor: Emory University • Aim: Knowledge-focused
Last updated Jul 01, 2026 00:00 UTC
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Kidney disease in kids: a closer look at Long-Term health
Knowledge-focused Recruiting nowThe Division of Kidney, Urologic, and Hematologic Diseases (DKUHD) of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), in collaboration with the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) and the National H…
Sponsor: Johns Hopkins Bloomberg School of Public Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:09 UTC