Could a Stool-Based pill tame ulcerative colitis?
NCT ID NCT05852574
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This early-phase study tests CP101, an oral capsule made from healthy donor stool, in 30 adults with mild-to-moderate ulcerative colitis. The goal is to see if the drug can safely restore a healthy gut microbiome and improve symptoms. Participants receive either a short or extended course of CP101 and are monitored for 24 weeks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- CP101 (an oral microbiome drug made from donor stool)
- What this could lead to
- If it works, this could point toward a new way to treat ulcerative colitis by restoring healthy gut bacteria.
- What could go wrong
- This is a very early (Phase 1) and small (30 people) study, so it may not show clear benefit or could have side effects. Success is far from guaranteed.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Brigham and Women's Hospital
Boston, Massachusetts, 02115, United States
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