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Blood test may help cancer patients avoid nerve damage from chemo

NCT ID NCT03987555

First seen Jan 04, 2026 · Last updated Jun 20, 2026 · Updated 31 times

Summary

This pilot study aims to see if doctors can consistently measure paclitaxel levels in the blood of cancer patients receiving the drug. The goal is to eventually adjust doses to give enough chemo to fight cancer while reducing the common side effect of nerve damage. The study involves 22 adults with various solid tumors and uses blood draws and surveys to track drug exposure and symptoms.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Wake Forest Baptist Comprehensive Cancer Center

    Winston-Salem, North Carolina, 27157, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

paclitaxel

What this could lead to

If successful, this could help doctors adjust paclitaxel doses to reduce nerve damage while still effectively treating cancer.

What could go wrong

This is a small, early feasibility study with only 22 participants and is currently suspended. It focuses on whether blood monitoring is practical, not on proving it improves outcomes.

Conditions

The condition(s) this trial relates to.

breast cancer breast carcinoma breast neoplasm cervical cancer cervical carcinoma invasive breast carcinoma lung cancer lung neoplasm metastatic neoplasm non-small cell lung carcinoma ovarian cancer ovarian carcinoma tumor of uterus uterine cancer Uterine Cervical Neoplasms vulva cancer vulvar carcinoma vulvar squamous cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.