STAGE IVA LUNG CANCER AJCC V8
Clinical trials for STAGE IVA LUNG CANCER AJCC V8 explained in plain language.
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Targeted pill shows promise for hard-to-treat cancers with rare mutations
Disease control Recruiting nowThis study tests a drug called avapritinib in people with advanced solid tumors that have certain genetic changes (CKIT or PDGFRA mutations). The goal is to see if the drug can shrink or control the cancer. About 50 adults with cancers like melanoma, sarcoma, or breast, lung, or …
Matched conditions: STAGE IVA LUNG CANCER AJCC V8
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 01, 2026 15:28 UTC
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New drug duo targets hard-to-treat lung cancer in early trial
Disease control Recruiting nowThis early-phase study tests two drugs, osimertinib and tegavivint, as the first treatment for people with a specific type of advanced lung cancer (EGFR-mutant NSCLC) that has spread. The main goal is to find the safest and most effective dose. About 24 adults with this cancer wi…
Matched conditions: STAGE IVA LUNG CANCER AJCC V8
Phase: PHASE1 • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Disease control
Last updated May 01, 2026 15:25 UTC
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New drug combo aims to extend life in tough lung cancer
Disease control Recruiting nowThis study tests a combination of chemotherapy (temozolomide) and immunotherapy (atezolizumab) in people with small cell lung cancer that has spread or returned after initial treatment. The goal is to see if this combo can shrink tumors and help patients live longer. About 56 adu…
Matched conditions: STAGE IVA LUNG CANCER AJCC V8
Phase: PHASE2 • Sponsor: Dwight Owen • Aim: Disease control
Last updated Apr 30, 2026 15:52 UTC
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New drug duo targets tough lung cancer
Disease control Recruiting nowThis early-stage trial tests a new drug (MRX-2843) combined with a standard targeted therapy (osimertinib) for people with advanced EGFR-mutant non-small cell lung cancer. The goal is to find the safest dose and see how well the combination works. About 69 participants will be en…
Matched conditions: STAGE IVA LUNG CANCER AJCC V8
Phase: PHASE1 • Sponsor: Emory University • Aim: Disease control
Last updated Apr 30, 2026 15:49 UTC
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Custom-Made cancer vaccine shows promise in advanced tumors
Disease control Recruiting nowThis study tests a personalized vaccine made from a patient's own tumor proteins, combined with the immunotherapy drug pembrolizumab, for people with advanced solid tumors. The goal is to see if this combination is safe and helps the immune system attack cancer more effectively. …
Matched conditions: STAGE IVA LUNG CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Apr 29, 2026 15:15 UTC
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Glow-in-the-Dark dye could help surgeons spot lung cancer
Diagnosis Recruiting nowThis study tests a special dye that attaches to lung cancer cells and makes them glow under a camera during surgery. The goal is to help surgeons see and remove all cancer tissue more accurately. About 30 adults with lung cancer or lung metastases will receive the dye before thei…
Matched conditions: STAGE IVA LUNG CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: Stanford University • Aim: Diagnosis
Last updated May 01, 2026 15:25 UTC
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Yoga may ease cancer treatment side effects for patients and families
Symptom relief Recruiting nowThis study tests whether a special yoga program can improve physical function, fatigue, sleep, and quality of life for people with lung or esophageal cancer who are getting radiation therapy, and also for their family caregivers. About 400 patient-caregiver pairs will take part. …
Matched conditions: STAGE IVA LUNG CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated May 01, 2026 15:28 UTC
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Smart radiation planning may cut lung cancer treatment side effects
Symptom relief Recruiting nowThis study looks at whether updating radiation treatment plans at set times during therapy can lower side effects for people with non-small cell lung cancer. As tumors shrink from radiation, healthy tissue can get exposed, so researchers want to see if planned re-designs help. Ab…
Matched conditions: STAGE IVA LUNG CANCER AJCC V8
Phase: NA • Sponsor: Rutgers, The State University of New Jersey • Aim: Symptom relief
Last updated May 01, 2026 15:24 UTC