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Could a poop transplant fix cancer treatment side effects?

NCT ID NCT03819296

Recruiting now Knowledge-focused Sponsor: M.D. Anderson Cancer Center Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated Jun 13, 2026 · Updated 28 times

Summary

This study looks at how the bacteria in your gut might cause stomach issues like diarrhea and colitis when you take certain cancer drugs called immune checkpoint inhibitors. Researchers will collect stool, blood, and tissue samples from 800 people with melanoma, lung cancer, or genitourinary cancers to understand these side effects. They will also test whether a fecal transplant (putting healthy donor stool into the patient) can help improve symptoms.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • M D Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

The condition(s) this trial relates to.

cancer colitis cutaneous melanoma lung neoplasm metastatic melanoma non-small cell lung carcinoma Urogenital Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CLINICAL STAGE 0 CUTANEOUS MELANOMA AJCC V8 CLINICAL STAGE I CUTANEOUS MELANOMA AJCC V8 CLINICAL STAGE IA CUTANEOUS MELANOMA AJCC V8 CLINICAL STAGE IA CUTANEOUS MELANOMA AJCC V8 CLINICAL STAGE IB CUTANEOUS MELANOMA AJCC V8 CLINICAL STAGE IB CUTANEOUS MELANOMA AJCC V8 CLINICAL STAGE II CUTANEOUS MELANOMA AJCC V8 CLINICAL STAGE II CUTANEOUS MELANOMA AJCC V8 CLINICAL STAGE IIA CUTANEOUS MELANOMA AJCC V8 CLINICAL STAGE IIA CUTANEOUS MELANOMA AJCC V8 CLINICAL STAGE IIB CUTANEOUS MELANOMA AJCC V8 CLINICAL STAGE IIB CUTANEOUS MELANOMA AJCC V8 CLINICAL STAGE IIC CUTANEOUS MELANOMA AJCC V8 CLINICAL STAGE III CUTANEOUS MELANOMA AJCC V8 CLINICAL STAGE III CUTANEOUS MELANOMA AJCC V8 CLINICAL STAGE IV CUTANEOUS MELANOMA AJCC V8 CLINICAL STAGE IV CUTANEOUS MELANOMA AJCC V8 COLITIS LUNG NON-SMALL CELL CARCINOMA MALIGNANT GENITOURINARY SYSTEM NEOPLASM MALIGNANT SOLID NEOPLASM PATHOLOGIC STAGE 0 CUTANEOUS MELANOMA AJCC V8 PATHOLOGIC STAGE I CUTANEOUS MELANOMA AJCC V8 PATHOLOGIC STAGE I CUTANEOUS MELANOMA AJCC V8 PATHOLOGIC STAGE IA CUTANEOUS MELANOMA AJCC V8 PATHOLOGIC STAGE IA CUTANEOUS MELANOMA AJCC V8 PATHOLOGIC STAGE IB CUTANEOUS MELANOMA AJCC V8 PATHOLOGIC STAGE IB CUTANEOUS MELANOMA AJCC V8 PATHOLOGIC STAGE IB CUTANEOUS MELANOMA AJCC V8 PATHOLOGIC STAGE II CUTANEOUS MELANOMA AJCC V8 PATHOLOGIC STAGE II CUTANEOUS MELANOMA AJCC V8 PATHOLOGIC STAGE IIA CUTANEOUS MELANOMA AJCC V8 PATHOLOGIC STAGE IIA CUTANEOUS MELANOMA AJCC V8 PATHOLOGIC STAGE IIB CUTANEOUS MELANOMA AJCC V8 PATHOLOGIC STAGE IIB CUTANEOUS MELANOMA AJCC V8 PATHOLOGIC STAGE IIC CUTANEOUS MELANOMA AJCC V8 PATHOLOGIC STAGE IIC CUTANEOUS MELANOMA AJCC V8 PATHOLOGIC STAGE III CUTANEOUS MELANOMA AJCC V8 PATHOLOGIC STAGE III CUTANEOUS MELANOMA AJCC V8 PATHOLOGIC STAGE IIIA CUTANEOUS MELANOMA AJCC V8 PATHOLOGIC STAGE IIIA CUTANEOUS MELANOMA AJCC V8 PATHOLOGIC STAGE IIIB CUTANEOUS MELANOMA AJCC V8 PATHOLOGIC STAGE IIIC CUTANEOUS MELANOMA AJCC V8 PATHOLOGIC STAGE IIID CUTANEOUS MELANOMA AJCC V8 PATHOLOGIC STAGE IV CUTANEOUS MELANOMA AJCC V8 PATHOLOGIC STAGE IV CUTANEOUS MELANOMA AJCC V8 STAGE 0 LUNG CANCER AJCC V8 STAGE 0 LUNG CANCER AJCC V8 STAGE I LUNG CANCER AJCC V8 STAGE I LUNG CANCER AJCC V8 STAGE IA1 LUNG CANCER AJCC V8 STAGE IA1 LUNG CANCER AJCC V8 STAGE IA2 LUNG CANCER AJCC V8 STAGE IA2 LUNG CANCER AJCC V8 STAGE IA3 LUNG CANCER AJCC V8 STAGE IA3 LUNG CANCER AJCC V8 STAGE IB LUNG CANCER AJCC V8 STAGE IB LUNG CANCER AJCC V8 STAGE II LUNG CANCER AJCC V8 STAGE II LUNG CANCER AJCC V8 STAGE IIA LUNG CANCER AJCC V8 STAGE IIA LUNG CANCER AJCC V8 STAGE IIB LUNG CANCER AJCC V8 STAGE IIB LUNG CANCER AJCC V8 STAGE III LUNG CANCER AJCC V8 STAGE III LUNG CANCER AJCC V8 STAGE IIIA LUNG CANCER AJCC V8 STAGE IIIA LUNG CANCER AJCC V8 STAGE IIIB LUNG CANCER AJCC V8 STAGE IIIB LUNG CANCER AJCC V8 STAGE IIIC LUNG CANCER AJCC V8 STAGE IIIC LUNG CANCER AJCC V8 STAGE IV LUNG CANCER AJCC V8 STAGE IV LUNG CANCER AJCC V8 STAGE IVA LUNG CANCER AJCC V8 STAGE IVA LUNG CANCER AJCC V8 STAGE IVB LUNG CANCER AJCC V8 STAGE IVB LUNG CANCER AJCC V8