CLINICAL STAGE III CUTANEOUS MELANOMA AJCC V8
Clinical trials for CLINICAL STAGE III CUTANEOUS MELANOMA AJCC V8 explained in plain language.
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New drug combo trial hopes to tame advanced cancers
Disease control Recruiting nowThis early-phase study tests a new drug called IACS-6274, given alone or with other medicines, in people with advanced solid tumors (like melanoma, ovarian, or head and neck cancers). The main goal is to find the safest dose and understand side effects. About 54 adults will take …
Matched conditions: CLINICAL STAGE III CUTANEOUS MELANOMA AJCC V8
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 26, 2026 04:17 UTC
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New hope for kidney transplant patients with advanced skin cancer: immune-boosting combo tested
Disease control Recruiting nowThis study tests whether combining two immunotherapy drugs (nivolumab and ipilimumab) with two anti-rejection medications (sirolimus and prednisone) can control advanced skin cancer in kidney transplant recipients without losing the transplanted kidney. About 16 adults with skin …
Matched conditions: CLINICAL STAGE III CUTANEOUS MELANOMA AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 26, 2026 03:58 UTC
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New combo therapy aims to shrink tough cancers using biomarker clues
Disease control Recruiting nowThis study tests two drugs—cabozantinib and nivolumab—in people with advanced melanoma or head and neck cancer that has stopped responding to other treatments. The goal is to see if the combination can shrink or stabilize the cancer, and whether certain tumor biomarkers can predi…
Matched conditions: CLINICAL STAGE III CUTANEOUS MELANOMA AJCC V8
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 26, 2026 03:54 UTC
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Custom-Made cancer vaccine shows promise in advanced tumors
Disease control Recruiting nowThis study tests a personalized vaccine made from a patient's own tumor proteins, combined with the immunotherapy drug pembrolizumab, for people with advanced solid tumors (like breast, lung, or skin cancer). The goal is to see if the combination is safe and helps the immune syst…
Matched conditions: CLINICAL STAGE III CUTANEOUS MELANOMA AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated May 22, 2026 14:04 UTC
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Cancer patients may soon get infusions at home, cutting travel and stress
Symptom relief Recruiting nowThis study tests whether giving the cancer drug nivolumab as a shot at home is as safe and effective as getting it in a clinic. About 50 adults with various cancers will try both settings to see which they prefer and how it affects their quality of life. The goal is to reduce the…
Matched conditions: CLINICAL STAGE III CUTANEOUS MELANOMA AJCC V8
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated May 26, 2026 04:19 UTC
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Blood tests may reveal why some cancers resist immunotherapy
Knowledge-focused Recruiting nowThis study looks at how immune cells called T cells change in people with advanced melanoma, lung cancer, or other solid tumors during anti-PD-1 treatment. Researchers will measure specific markers in blood samples to see if they can predict whether the therapy is working or if r…
Matched conditions: CLINICAL STAGE III CUTANEOUS MELANOMA AJCC V8
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated May 26, 2026 04:16 UTC
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Gut bacteria may hold key to easing cancer treatment side effects
Knowledge-focused Recruiting nowThis study looks at how the bacteria in your gut might influence stomach issues like diarrhea and colitis caused by certain cancer drugs (immune checkpoint inhibitors). Researchers will collect stool, blood, and tissue samples from 800 people with melanoma, lung cancer, or genito…
Matched conditions: CLINICAL STAGE III CUTANEOUS MELANOMA AJCC V8
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated May 19, 2026 11:48 UTC
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Can your social life help you beat Cancer's aftermath?
Knowledge-focused Recruiting nowThis study follows 250 young adults (ages 18-39) recently diagnosed with cancer to see how their social relationships and physical activity change over time and affect their quality of life. Researchers will track hospitalizations, treatment details, exercise habits, and well-bei…
Matched conditions: CLINICAL STAGE III CUTANEOUS MELANOMA AJCC V8
Sponsor: University of Southern California • Aim: Knowledge-focused
Last updated May 18, 2026 11:59 UTC