STAGE I LUNG CANCER AJCC V8

This study tests whether artificial intelligence can help doctors choose the right radiation dose for each person's lung tumor. About 70 adults with lung cancer or tumors that spread to the lung will receive stereotactic body radiation therapy (SBRT) with doses guided by an AI to…

This study tests whether doing special breathing exercises before lung cancer surgery can lower the chance of problems like pneumonia or breathing trouble after the operation. About 220 people with stage I-IIIB lung cancer will either do the training or receive usual care. The go…

This study tests whether the drug canakinumab can prevent lung cancer in people who have suspicious lung nodules that haven't gone away. About 50 participants will receive the drug to see if their nodules shrink or disappear, and to track how many develop lung cancer over time. T…

This study tests whether a home-based breathing exercise program can help lung cancer survivors (stages I-III) who often struggle with shortness of breath, fatigue, and low fitness after surgery. About 100 participants will do breathing exercises regularly for several weeks. Rese…

This study tests whether a special yoga program can improve physical function, fatigue, sleep, and quality of life for people with lung or esophageal cancer who are getting radiation therapy, and also for their family caregivers. About 400 patient-caregiver pairs will take part. …

This study looks at two different ways surgeons cut blood vessels during lung cancer surgery. The goal is to see if tying off the vein first (instead of the artery) reduces the amount of tumor DNA released into the bloodstream. About 100 adults with early-stage lung cancer will h…

This study looks at how the bacteria in your gut might influence stomach issues like diarrhea and colitis caused by certain cancer drugs (immune checkpoint inhibitors). Researchers will collect stool, blood, and tissue samples from 800 people with melanoma, lung cancer, or genito…

This study looks at whether giving early-stage lung cancer patients information about quality of life helps them choose between surgery and radiation therapy. About 150 adults with stage I-II lung cancer who can have either treatment will take part. The goal is to see if this inf…