University Of Washington

This study tested whether a team-based care model can help people with both opioid use disorder and mental health issues like depression or anxiety. 254 adults in primary care received either full collaborative care for both conditions or just mental health support. The goal was …

This completed study tested whether reducing loneliness through group therapy could lower opioid misuse in 102 adults on long-term opioids for chronic pain. Participants received either cognitive behavior therapy or social navigation in weekly sessions. Researchers measured chang…

This large Phase 3 trial tested whether giving erythropoietin (Epo) to extremely premature infants within 24 hours of birth could reduce death or severe neurodevelopmental problems. Over 900 babies born between 24 and 27 weeks of pregnancy were enrolled. The study compared Epo in…

This study tested a new combination of drugs for people with Hodgkin lymphoma that either returned after treatment or didn't respond. The goal was to find the safest dose of a targeted drug (brentuximab vedotin) when added to standard chemotherapy. 45 adults took part, and the st…

This massive study tested whether giving deworming medicine (albendazole) to everyone in a community, not just children, can break the cycle of soil-transmitted worm infections. Over 350,000 people in India, Malawi, and Benin took part. The goal was to see if treating entire vill…

This pilot study tested whether giving a combination of immunotherapy (pembrolizumab) and chemotherapy before surgery could help people with rare types of muscle-invasive bladder cancer. 17 participants received the treatment to see if it could eliminate all signs of cancer at th…

This study tested whether a culturally tailored diabetes education program, called Compañeros en Salud, combined with a continuous glucose monitor (CGM) helps Latinx adults with type 2 diabetes control their blood sugar better than education alone. 120 adults aged 18-60 with an A…

This study tested a combination of three targeted drugs (mosunetuzumab, polatuzumab vedotin, and obinutuzumab) in 42 people with untreated slow-growing B-cell non-Hodgkin lymphoma. The goal was to see how many patients achieved a complete response (no cancer detected). The drugs …

This study tested the drug nivolumab in 20 adults with blood cancers (like lymphoma, leukemia, or myeloma) that returned or did not respond after CAR T-cell therapy. Nivolumab is an immunotherapy that helps the body's immune system attack cancer cells. The goal was to see if it c…

This study tested a new treatment for men with prostate cancer that stopped responding to standard hormone therapy. The approach used high doses of testosterone along with a drug called olaparib to damage cancer cells' DNA and make them die. 36 men took part, and researchers meas…

This study tested a new insulin dosing calculator for adults with type 2 diabetes when they are admitted to the hospital. The goal was to see if the calculator could help control blood sugar without causing dangerously low levels. 38 participants received their first insulin dose…

This pilot study tested whether giving a mix of glucose, insulin, and potassium (GIK) during abdominal surgery can reduce serious complications in patients who do not have diabetes. About 106 adults took part to see if the treatment is practical and safe. The goal is to plan a la…

This study looked at whether offering HIV prevention services, including PrEP medication, in family planning clinics could help more young women in Kenya get tested for HIV and start prevention. Over 25,000 sexually active, HIV-negative women aged 15-24 were included. The goal wa…

This study tested whether a Mediterranean-style diet could help prevent episodes of diverticulitis, a painful digestive condition. 71 adults who had recently recovered from a diverticulitis attack were randomly assigned to follow either a Mediterranean diet or standard high-fiber…

This study tested whether giving TB prevention medicine in the community with fewer refill visits helps more people finish their treatment compared to the usual monthly clinic visits. 301 adults in South Africa who were at risk for TB took part. The goal was to see if the communi…

This study looked at different ways to help young women in South Africa, ages 18-25, take their daily HIV prevention pill (PrEP) consistently. The goal was to find the best support strategies to keep them protected from HIV. 360 women took part in the study, which tested a step-b…

This study tested whether taking a weekly dose of the antibiotic doxycycline can prevent bacterial sexually transmitted infections (STIs) in cisgender women who are already taking daily PrEP to prevent HIV. The study involved 60 women aged 18-30 in Kisumu, Kenya, and focused on m…

This study tested a pop-up clinic inside a van for women who inject drugs and exchange sex in north Seattle. The goal was to see if offering HIV prevention pills, addiction medications, and quick STI testing in a convenient location would help more women start and stay on these t…

This study looked at how safe and effective a daily HIV prevention pill (TAF-FTC) is in 54 Kenyan cisgender women. Participants took different numbers of doses each week to mimic real-world use. The goal was to measure drug levels in the blood and tissues, helping doctors better …

This phase 1 trial tested whether a second psilocybin-assisted group therapy retreat is safe and helpful for anxiety in 15 patients with metastatic cancer who had only a partial response to their first retreat. Psilocybin, the active ingredient in magic mushrooms, is given in a g…

This study tested a web app called Rose that provides hypnosis audio recordings for people with chronic pain. 100 adults with chronic low back pain or other chronic pain used the app for 8 weeks. The researchers measured how often people used it, their satisfaction, and changes i…

This study tested two brief, video-based therapies for women who experienced sexual assault and now struggle with PTSD and heavy drinking. One therapy focused on facing trauma memories, the other on building healthier drinking habits. The goal was to see if these short treatments…

This study tested a program where pregnant people could text with a trained peer mentor for support. 127 participants in Washington state were split into two groups: one could text a mentor, the other got automated messages. The mentor group had lower anxiety six weeks after givi…

This phase 2 trial looked at whether adding acupuncture and acupressure to oral cryotherapy (sucking on ice chips) can reduce nerve pain caused by oxaliplatin chemotherapy in people with gastrointestinal cancers. 78 patients were split into two groups: one got cryotherapy alone, …

This study tested a new type of prosthetic socket called the NU-FlexSIS for people who have a leg amputation above the knee and have limited mobility. The goal was to see if this socket is more comfortable and allows more wear time than the standard socket. 84 participants used b…

This study tested whether a smartphone app called FOCUS, along with coaching from trained clinicians, could help people with serious mental illnesses like schizophrenia and bipolar disorder. 191 participants used the app and received coaching over 12 weeks. Researchers measured c…

This study tested a program called PRISM to help adults with congenital heart disease build resilience and manage stress. 78 adults with moderate or complex heart conditions took part. Researchers checked if the program was feasible and if it improved resilience scores compared t…

This study looked at ways to help people who had a stroke use a CPAP machine for sleep apnea during their rehab stay. Sleep apnea is common after stroke and can slow recovery. The researchers tested different approaches to improve how often patients used the CPAP machine over thr…

This study tested a program called PRISM, which teaches skills like stress management and goal setting, to see if it helps racial minority patients with serious illnesses feel more resilient and communicate better with their healthcare providers. The study enrolled 28 seriously i…

This study tested a single-session website called SPARK Coping in 50 college students who have early signs of psychosis risk. The goal was to see if the tool is easy to use and helps reduce distress and stigma while improving attitudes toward treatment. Participants completed sur…

This study tested a text-message chatbot called Cecebot that combines sleep therapy and activity tips to help breast cancer survivors with insomnia. 60 women with stage I-III breast cancer and poor sleep used the chatbot for 6 weeks. The goal was to see if it was easy to stick wi…

This study tested whether using virtual reality (VR) can lower the pain people feel from short, hot but tolerable pokes on the skin. 24 healthy adults rated their pain with and without VR, and also when getting one poke versus two at the same time. The goal was to see if VR can b…

This study tested a web-based program for college women who have experienced sexual assault and drink heavily. The program teaches skills to manage emotions and cope with distress, aiming to reduce drinking. 200 women from the University of Washington took part. The goal was to s…

This study tested a new, non-invasive treatment for people with cervical spinal cord injury who have difficulty using their hands and arms. Fifteen participants received either electrical stimulation of the spinal cord combined with physical therapy, or physical therapy alone. Th…

This study tested whether a pharmaceutical-grade psilocybin, given in a group therapy setting, is safe and can help reduce anxiety and depression in people with metastatic cancer. 55 adults with advanced cancer took part. The goal was to see if this approach could ease emotional …

This study looked at whether acupuncture can reduce pain in people with long COVID. 93 adults with ongoing pain after a COVID infection were randomly assigned to receive either 8 acupuncture sessions or their usual care. Researchers measured pain intensity and its impact on daily…

This study tested two mobile health (mHealth) strategies to help people with schizophrenia manage their symptoms. 299 participants used smartphone tools to track and improve issues like depression, anxiety, and insomnia. The goal was to see if these digital tools could make a rea…

This study tested a trauma-focused therapy (TF-CBT) for young people aged 8 to 19 who had experienced trauma and had PTSD symptoms. The therapy was delivered in schools to make it easier for students to get help. Researchers also tested a strategy to help school clinicians adopt …

This study tested if using buffered lidocaine (a less acidic numbing medicine) reduces pain during prostate biopsy. 350 men scheduled for a biopsy rated their pain after the injection. The goal was to see if this simple change, already used in other procedures, could make the exp…

This study looked at whether walking in nature can help reduce depressive symptoms in college students more than walking in a city. 138 students with mild to moderate depression were randomly assigned to take 30-minute walks twice a week for three weeks in either a natural settin…

This study tested a comprehensive self-management program for people with inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease. The program included eight sessions covering topics like symptom tracking, relaxation, diet, and pain management. Research…

This study tested a mobile app designed to help people with chronic pain manage their symptoms and improve daily life. 108 adults with chronic pain used the app, which also offered an optional activity tracker. The goal was to see if the app is easy to use and can reduce how much…

This study looked at whether three types of cognitive behavioral therapy (CBT) delivered online could help reduce fatigue in people with multiple sclerosis. 21 adults with MS and chronic fatigue tried relaxation training, behavioral activation, or cognitive therapy. The goal was …

This study tested whether giving comic books and videos about COVID-19 safety to students and parents could reduce school absences due to illness. Over 1,000 people from rural Latino communities in Washington state took part. The goal was to see if simple educational materials co…

This completed study tested whether immersive virtual reality can distract people and reduce their memory of events. Twenty healthy adults wore VR goggles and tried to memorize words while in a virtual world. Researchers measured how many words they recalled and how distracted th…

This completed study collected blood, urine, and kidney tissue from 90 COVID-19 patients with acute kidney injury. Researchers aimed to build a biorepository and analyze samples to better understand how COVID-19 affects the kidneys. The goal is to speed up discoveries and improve…

This study tested whether a special ultrasound with a contrast agent (DEFINITY®) can measure blood flow in the spinal cord during surgery for acute spinal cord injury. 27 patients received the contrast agent while surgeons performed routine decompression. The goal was to see if t…

This study measured how much energy children with cerebral palsy use while walking, with and without harness support. 34 children aged 8-17 walked on a treadmill while researchers tracked their oxygen use and movement. The goal was to understand what makes walking so tiring for t…

This completed study looked at how gender-affirming testosterone therapy changes the way the body processes other medications. Fourteen transgender adults who were about to start testosterone therapy took small doses of three common drugs (midazolam, digoxin, and acetaminophen) b…

This study tested a mentoring program for women in the sheet metal trade. The goal was to see if having a mentor could reduce stress, prevent injuries, and improve job satisfaction. 96 women sheet metal workers took part. The program paired experienced workers with newer ones to …

This study tested whether online health messages and texts can help young adults (ages 18-24) who choose to drink have safer, more positive experiences. 35 participants in Washington State were randomly assigned to receive the messages or just fill out surveys. The main goal was …

This study tested whether immersive virtual reality affects memory and distraction. 16 healthy adults tried to remember word lists while either using VR or not. The goal was to see if VR changes how well we recall information and how distracted we feel.

This study looked at how young children with Down syndrome, cerebral palsy, and other motor delays move and explore when using a powered mobility device called the Explorer Mini and a bodyweight support system. Sixteen children who could sit upright but not walk 10 feet on their …

This study tested whether a clinical pharmacist could reduce medication-related problems when patients move from the hospital to a skilled nursing facility. Over 1,000 adults took part, and the pharmacist reviewed their medicines during the transition. The goal was to see if this…

This study tested a new artificial intelligence tool called CBTpro that helps therapists improve their skills in cognitive behavioral therapy for people with psychosis. Over 600 participants, including clients with conditions like schizophrenia and bipolar disorder, took part. Th…

This study tested a mobile app designed to help caregivers of young adults (ages 15-35) with early psychosis. The app provided interactive lessons to improve caregivers' knowledge and coping skills, aiming to reduce how long psychosis goes untreated. Sixty caregivers in the U.S. …

This study worked with 13 formerly incarcerated parents and their families to adapt a parenting support program. Re-entry navigators with lived experience delivered the program. The goal was to improve parent well-being and parenting skills, and to prevent hardship from passing t…

This study tested whether oxytocin nasal spray helps people with social anxiety disorder learn safety from watching others. About 120 adults received either oxytocin or a placebo and underwent brain scans. The goal was to see if oxytocin improves the brain's ability to tell threa…

This study looked at how psychological stress affects the decision to drink alcohol in people who drink regularly. 160 participants were split into four groups, some exposed to stress and some not, and given a choice between alcoholic and non-alcoholic drinks. The goal was to und…

This study aimed to understand the challenges Spanish-speaking patients face when leaving the hospital for a nursing facility. Researchers interviewed 17 patients and caregivers to identify communication barriers and what helps or hinders a smooth transition. The goal is to use t…

This study looked at 112 people to see if brain inflammation (called gliosis) affects weight loss and regain. Researchers used MRI scans to compare people who lost weight through diet or surgery. The goal was to learn why weight often returns after dieting and how the brain might…

This study tested a short home-visiting program for birth parents whose young children (ages 1-5) had been returned to them after foster care. The goal was to see if the program could improve parenting skills and reduce the chance of children being removed again. 264 parents took…

This study tested whether an AI scribe that listens to doctor-patient conversations can reduce doctor burnout and improve patient satisfaction. 139 doctors and advanced practice providers from primary care, oncology, and urology were randomly assigned to use the AI scribe or cont…

This study looked at how two hormones that rise during pregnancy—estradiol and cortisol—affect the way the body breaks down THC, the main active ingredient in cannabis. Fourteen healthy women of childbearing age took part. Researchers measured THC levels in the blood after taking…

This study looked at how alcohol changes attention in young adults aged 21-25 who drink regularly. Participants completed simple phone-based games to measure focus before and after drinking alcohol, both in a lab and during their daily lives over eight weekends. The goal was to u…

This study looked at how gender-affirming estrogen therapy changes the way the body processes other medications. Twenty-two transgender adults who were not yet on estrogen took part. Researchers measured how two common drugs (midazolam and digoxin) were handled before and after s…

This study looked at how the brain naturally reduces pain when a person feels two painful sensations at the same time. Researchers wanted to see if paying attention to one pain can help turn down the other. Twenty-four healthy University of Washington students took part, rating t…