University Of South Florida

This study tests whether a pharmacist-led program using a continuous glucose monitor (CGM) can help people with prediabetes better control their blood sugar and make healthier choices. Forty adults with prediabetes will wear a CGM sensor for 12 weeks and receive pharmacist guidan…

This study tests whether adding a special medical food that restricts certain amino acids (NEAAR) to standard cancer therapy (radiation and chemotherapy) is safe and tolerable for people with locally advanced rectal cancer. About 30 adults will participate. The goal is to see if …

This pilot study tests whether having a pharmacist oversee continuous glucose monitoring (using a FreeStyle Libre device) can improve blood sugar control and health behaviors in people with type 2 diabetes. Forty participants will use the monitor for 12 weeks, and their results w…

This study is for women aged 18 to 40 with pelvic cancer who need radiation therapy. The surgery moves the uterus and ovaries away from the radiation area to protect them. The goal is to see if this is safe and helps preserve the ability to have children in the future.

This study is testing a device called ShuntCheck that uses a simple, non-invasive skin test to see if a shunt (a tube that drains fluid from the brain) is working properly. The study will include 50 adults aged 40 and older who have a shunt for normal pressure hydrocephalus but h…

This study checks if a device called ShuntCheck can accurately find blockages in shunts used to drain fluid from the brain in people with normal pressure hydrocephalus. About 20 adults aged 40 and older with suspected shunt problems will be tested. The goal is to see if ShuntChec…

This study tests a procedure called Immediate Lymphatic Reconstruction (ILR) done during breast cancer surgery to prevent lymphedema, a painful arm swelling. About 98 high-risk women will be randomly assigned to receive ILR or standard care. Researchers will track who develops ly…

This study is testing a web-based version of cognitive behavioral therapy for insomnia (CBT-I) in 60 dementia caregivers who have chronic insomnia. The program includes four online sessions covering sleep hygiene, relaxation, and changing unhelpful thoughts about sleep. Researche…

This study tests whether dry needling—a treatment using thin needles to target tight muscles—can reduce chronic lower-limb pain in people with multiple sclerosis. Twenty-four participants will receive either real or sham dry needling over six sessions. Researchers also hope to se…

This study tests a new speech therapy technique for people with aphasia (trouble speaking) after a stroke. Instead of copying a therapist's voice, participants will practice speaking along with an AI-cloned version of their own voice. The goal is to see if this personalized appro…

This study looks at whether people with heart pain or mild heart attacks need to fast before an urgent heart catheterization. Researchers want to see if eating and drinking before the procedure makes patients more comfortable without causing safety problems like vomiting or breat…

This study tests whether breathing pure oxygen in a pressurized chamber (hyperbaric oxygen therapy) can reduce long-term symptoms like headaches, memory loss, and mood problems in 420 veterans with mild to moderate traumatic brain injury. Participants will attend 40 sessions over…

This study tests two behavioral treatments for chronic insomnia in 165 adults with chronic pain who take prescribed opioids. The goal is to see if improving sleep can also help reduce opioid use. Participants will be randomly assigned to one of the treatments and monitored for ch…

This study tests whether a new eye drop called acoltremon can help people with a specific type of dry eye caused by early nerve damage (stage 1 neurotrophic keratopathy). The study will include 50 adults who have both decreased tear production and reduced corneal sensation. Resea…

This study tests a program called ACT Together for parents of children with disabilities. The program includes six online lessons and weekly phone coaching sessions with a trained therapist. It teaches skills to handle stress and difficult emotions. Researchers want to see if the…

This study tests two group-based parent training programs (HOT DOCS and DOCS K-5) for caregivers of children ages 0-12 with disruptive behaviors or developmental delays. The goal is to reduce child behavior problems and lower parenting stress. Researchers will enroll 800 English-…

This study looks at how your blood sugar level changes your motivation to be active or to rest. Forty healthy adults will exercise, drink a sugary beverage, or a sugar-free drink, and then report their desire to move or rest. The goal is to understand the link between blood gluco…

This study looks at how remembering a loved one affects the heart rate and blood pressure of young adults who have lost someone in the last 2 to 18 months. Researchers want to see if a quick self-affirmation exercise (thinking about your core values) can help calm the body's stre…

This study follows 50 adults with certain types of hearing loss for 3 years to see if using a bone-anchored hearing device (called an OID) helps maintain or improve thinking skills like memory and attention. Participants will take thinking and memory tests at the start and after …

This study looks at how older adults with hearing loss understand speech in noisy settings, and how hearing aids can help. Researchers will test 121 people, including young and older adults with normal hearing and older adults with hearing loss. They will measure both behavior (l…

This study tests whether a very brief, persuasive message—delivered by a video or a counselor—can increase HIV and hepatitis C testing among emergency room patients who initially said no. About 2,000 adults who speak English or Spanish and haven't been tested in the past year wil…