University Of South Florida
Clinical trials sponsored by University Of South Florida, explained in plain language.
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Pharmacists use High-Tech monitors to tackle prediabetes
Disease control Recruiting nowThis study looks at whether a pharmacist-led program using a continuous glucose monitor (CGM) can help people with prediabetes better control their blood sugar and make healthier choices. About 40 adults aged 18-70 with prediabetes will wear a CGM for 4 weeks and receive pharmaci…
Sponsor: University of South Florida • Aim: Disease control
Last updated Jun 16, 2026 13:33 UTC
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New surgery may help women with pelvic cancer preserve fertility
Disease control Recruiting nowThis study is for women aged 18 to 40 with pelvic cancer who need radiation therapy. The surgery moves the uterus and ovaries away from the radiation area to protect them. The goal is to see if this is safe and helps preserve the ability to have children in the future.
Phase: NA • Sponsor: University of South Florida • Aim: Disease control
Last updated Jun 16, 2026 12:55 UTC
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Can a simple test replace X-Rays for shunt checks?
Diagnosis Recruiting nowThis study is testing a device called ShuntCheck to see if it can correctly tell whether a shunt (a tube that drains fluid from the brain) is working in people with normal pressure hydrocephalus who have no symptoms. The study will include 50 adults aged 40 and older who already …
Sponsor: University of South Florida • Aim: Diagnosis
Last updated Jun 15, 2026 19:07 UTC
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New device could spot shunt blockages faster in brain fluid disorder
Diagnosis Recruiting nowThis study checks if a device called ShuntCheck can accurately find blockages in shunts used to drain fluid from the brain in people with normal pressure hydrocephalus. About 20 adults aged 40 and older with suspected shunt problems will be tested. The goal is to see if ShuntChec…
Sponsor: University of South Florida • Aim: Diagnosis
Last updated Jun 15, 2026 18:55 UTC
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New surgery aims to stop arm swelling in breast cancer patients
Prevention Recruiting nowThis study tests a surgical procedure called Immediate Lymphatic Reconstruction (ILR) to prevent lymphedema, a painful arm swelling, in women undergoing breast cancer surgery that removes lymph nodes. About 98 high-risk patients will be randomly assigned to receive ILR or standar…
Phase: NA • Sponsor: University of South Florida • Aim: Prevention
Last updated Jun 15, 2026 19:04 UTC
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Can parent training tame tough toddler tantrums? new study seeks 800 families
Symptom relief Recruiting nowThis study tests two group-based parent training programs (HOT DOCS and DOCS K-5) for caregivers of children ages 0-12 with disruptive behaviors or developmental delays. The goal is to reduce child behavior problems and lower parenting stress. Researchers will enroll 800 English-…
Phase: NA • Sponsor: University of South Florida • Aim: Symptom relief
Last updated Jun 16, 2026 13:02 UTC
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New eye drop hopes to bring tears to dry eyes damaged by nerve loss
Symptom relief Recruiting nowThis study tests whether a special eye drop called acoltremon can help people with stage 1 neurotrophic keratopathy (a condition where the cornea loses feeling) and dry eye produce more tears. About 50 adults will use the drops and have their tear production measured. The goal is…
Phase: PHASE4 • Sponsor: University of South Florida • Aim: Symptom relief
Last updated Jun 16, 2026 12:51 UTC
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New online program aims to end sleepless nights for dementia caregivers
Symptom relief Recruiting nowThis study tests a web-based program called NiteCAPP that teaches dementia caregivers skills to overcome insomnia. Caregivers often struggle with sleep due to the demands of caring for a loved one, which can lead to depression and poor health. The program is designed to be flexib…
Phase: NA • Sponsor: University of South Florida • Aim: Symptom relief
Last updated Jun 16, 2026 12:50 UTC
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Can pressurized oxygen heal Veterans' brain injuries?
Symptom relief Recruiting nowThis study tests whether breathing pure oxygen in a pressurized chamber (hyperbaric oxygen therapy) can reduce symptoms like headaches, memory problems, and mood changes in veterans and active military with mild to moderate traumatic brain injury. About 420 participants will rece…
Phase: PHASE3 • Sponsor: University of South Florida • Aim: Symptom relief
Last updated Jun 15, 2026 19:08 UTC
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Sleep therapy may cut opioid use in chronic pain patients
Symptom relief Recruiting nowThis study tests two behavioral programs designed to improve sleep in adults who have both chronic pain and chronic insomnia and who take prescribed opioids. The goal is to see if better sleep can help reduce pain and lower the need for opioid medication. Researchers will track s…
Phase: NA • Sponsor: University of South Florida • Aim: Symptom relief
Last updated Jun 15, 2026 19:03 UTC
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New online program aims to ease stress for parents of kids with disabilities
Symptom relief Recruiting nowThis study tests a program called ACT Together for parents of children with disabilities. The program includes six online lessons and weekly phone coaching sessions with a therapist. Researchers want to see if it is easy to use and if it helps parents feel less stressed and depre…
Phase: NA • Sponsor: University of South Florida • Aim: Symptom relief
Last updated Jun 15, 2026 19:03 UTC
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Your own voice may be the key to speaking again after stroke
Symptom relief Recruiting nowThis study tests a new speech therapy technique for people with aphasia (trouble speaking) after a stroke. Instead of copying a therapist's voice, participants will use an app that plays their own voice, altered by AI. The goal is to see if hearing their own voice helps them spea…
Phase: NA • Sponsor: University of South Florida • Aim: Symptom relief
Last updated Jun 15, 2026 18:55 UTC
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Fasting before heart caths questioned in new study
Knowledge-focused Recruiting nowThis study looks at whether people with chest pain or mild heart attacks need to fast before an urgent heart catheterization. About 400 participants will either fast or eat and drink as usual before their procedure. Researchers will measure comfort and safety to see if skipping f…
Phase: NA • Sponsor: University of South Florida • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:53 UTC
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Brain waves reveal secrets of hearing in noise for seniors
Knowledge-focused Recruiting nowThis study looks at how older adults with hearing loss understand speech in noisy settings, and how hearing aids can help. Researchers will test 121 people, including young and older adults with normal hearing and older adults with hearing loss. They will measure both behavior (l…
Phase: NA • Sponsor: University of South Florida • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:53 UTC
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Grief and heart health: could Self-Affirmation be the key?
Knowledge-focused Recruiting nowThis study looks at how recalling a loss affects heart rate and blood pressure in young adults who have lost a loved one in the past 2 to 18 months. Researchers want to see if a brief self-affirmation exercise (thinking about your core values) can help calm the body's stress resp…
Phase: NA • Sponsor: University of South Florida • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:08 UTC
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ER video nudge aims to boost HIV and hepatitis c testing
Knowledge-focused Recruiting nowThis study tests whether a very brief, persuasive message—delivered by a video or a counselor—can increase HIV and hepatitis C testing among emergency room patients who initially said no. About 2,000 adults who speak English or Spanish and haven't been tested in the past year wil…
Phase: NA • Sponsor: University of South Florida • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:02 UTC
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Sugar rush or slump? study probes blood Glucose's grip on motivation
Knowledge-focused Recruiting nowThis study looks at how blood sugar levels influence your desire to be active or to rest. Researchers will give 40 healthy adults a drink (with or without sugar) and have them exercise, then measure their motivation to move or relax. The goal is to understand the link between blo…
Phase: NA • Sponsor: University of South Florida • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:02 UTC