University Of Maryland, Baltimore

This study looks at whether using a continuous glucose monitor (CGM) after leaving the hospital helps people with diabetes control their blood sugar better than the usual finger-stick method. About 120 adults with diabetes and high blood sugar will be randomly assigned to use eit…

This study aims to develop and validate a blood test that detects DNA changes (epigenetic signatures) linked to pancreatic cancer. Researchers will collect blood samples and medical records from 450 adults with or at high risk for pancreatic cancer, following them for about 5 yea…

This study will test a smartphone-based program called HMP to help young sexual and gender minority (SGM) people start and stay on HIV prevention (PrEP) or treatment. About 1,500 participants aged 15-24 will be split into two groups: one gets HMP right away, the other gets it lat…

This study looks at whether using a small electrical stimulation device at home, along with regular clinic therapy, can reduce pain and improve movement in people with frozen shoulder (adhesive capsulitis). Ten adults with the condition will try the device for several weeks. Rese…

This study tests a wearable robot that helps people with traumatic brain injury (TBI) relearn movement while still in bed, even if they are paralyzed. The robot guides the ankle through exercises to improve motor and sensory function. The trial will enroll 100 adults aged 30-85 w…

This study tests whether a gradual exercise program, starting at a center and then moving to home, can safely improve mobility and strength in people aged 50+ with a recently healed diabetic foot ulcer. The goal is to help them walk farther and reduce their high risk of heart-rel…

This early-phase study tests whether a diabetes drug called glibenclamide (glyburide) can safely help nerve pain in people with multiple sclerosis. Ten adults with MS and moderate-to-severe nerve pain will take the drug and be monitored for side effects and pain changes. The goal…

This study tests a program called Fostering Positive Care Interactions in Assisted Living (FPCI-AL) to improve how staff interact with residents who have Alzheimer's or related dementias. The goal is to reduce distress and resistance during care, and increase engagement. The stud…

This study looks at whether a decision aid pamphlet can reduce anxiety and help people with low-risk thyroid cancer feel more ready to choose a treatment. About 34 participants will receive the pamphlet after diagnosis but before seeing a surgeon. The pamphlet explains treatment …

This study tests two simple activities—volunteering inside the assisted living community or joining a current events group—to see if they can reduce apathy in residents with mild to moderate memory issues. About 200 people aged 55+ will take part for 6 months, doing their assigne…

This study compares two standard radiation methods for cervical and endometrial cancer: proton therapy and photon therapy. The goal is to see which causes fewer stomach side effects like diarrhea. About 116 women with newly diagnosed cancer will take part, and they will be random…

This study looks at how healthy people respond to sitagliptin, an FDA-approved diabetes drug. Researchers want to understand why some people produce more insulin after taking the drug. About 400 healthy, non-diabetic volunteers from the Old Order Amish community will take part in…

This study will test two new risk scores that predict a patient's chance of developing sepsis or experiencing a serious decline (like cardiac arrest or unplanned ICU transfer) within the next four hours. Researchers will see if giving these scores to hospital staff leads to faste…

This study will develop and test a hub-based engagement navigator service for people aged 13-35 with early psychosis who are at risk of dropping out of care. The service will be created with input from patients, families, and clinic staff. Researchers will then test whether the s…

This study will test whether a smartphone app called Gingko Active can help middle-aged and older adults (45+) improve their strength, endurance, and balance better than following a standard exercise booklet. The study involves 60 healthy adults or those with controlled high bloo…

This study looks at how doctors treat pelvic fractures in people 60 and older. It aims to see if patients and surgeons are willing to join a future trial comparing surgery versus non-surgery. 120 participants will be followed to check if such a large study is possible.

This study aims to understand how the live attenuated influenza vaccine (nasal spray) affects immune cells in the tonsils and adenoids. Researchers will give the vaccine or no vaccine to 25 children scheduled for tonsil/adenoid removal for sleep apnea, then study the discarded ti…

This study looks at whether using a special fluid management approach (ACUMEN) during heart surgery can help prevent kidney damage. About 100 adults having heart bypass or valve surgery will take part. Researchers will measure kidney injury using blood and urine tests, and track …