University Of Maryland, Baltimore
Clinical trials sponsored by University Of Maryland, Baltimore, explained in plain language.
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Could a single pill prevent two types of diarrhea? early trial begins
⭐️ VACCINE ⭐️ CompletedThis early-stage study tested an oral vaccine designed to protect against two bacteria that cause severe diarrhea: Shigella and ETEC. Fifty-three healthy adults received the vaccine to check for side effects and to see if it triggers an immune response. The goal is to develop a s…
Phase: PHASE1 • Sponsor: University of Maryland, Baltimore • Aim: ⭐️ VACCINE ⭐️
Last updated May 01, 2026 16:01 UTC
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New drug combo shows promise for tough leukemia cases
Disease control CompletedThis early-stage trial tested a combination of two drugs, pegcrisantaspase and venetoclax, in 27 adults whose acute myeloid leukemia had returned or not responded to prior treatments. The main goals were to check safety and find the best dose. Researchers also looked at how many …
Phase: PHASE1 • Sponsor: University of Maryland, Baltimore • Aim: Disease control
Last updated May 01, 2026 16:00 UTC
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New program aims to help young adults with psychosis cut back on cannabis
Disease control CompletedThis study tested a program called the Teen Marijuana Check Up, adapted for young adults (ages 13-35) who have early psychosis and use cannabis. The program provided education on safer cannabis use and helped participants stay engaged in their mental health care. The goal was to …
Phase: NA • Sponsor: University of Maryland, Baltimore • Aim: Disease control
Last updated May 01, 2026 16:00 UTC
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Smart pens and sensors: a new way to tame diabetes?
Disease control CompletedThis pilot study tested whether using smart insulin pens together with continuous glucose monitors (CGMs) could improve blood sugar control in adults with type 2 diabetes. Thirty participants used these devices for six months. The main goal was to see if their average blood sugar…
Phase: NA • Sponsor: University of Maryland, Baltimore • Aim: Disease control
Last updated Apr 26, 2026 20:00 UTC
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Robots and electricity join forces to restore arm movement after stroke
Symptom relief CompletedThis study tested whether combining robotic therapy with electrical stimulation helps people with chronic stroke regain arm movement better than robotic therapy alone. Twenty-four adults who had a stroke more than six months ago participated. The goal was to improve smoothness, s…
Phase: NA • Sponsor: University of Maryland, Baltimore • Aim: Symptom relief
Last updated May 01, 2026 15:58 UTC
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Could celery compound ease schizophrenia?
Symptom relief CompletedThis study tested whether luteolin, a natural substance found in celery and chamomile tea, can help improve symptoms of schizophrenia. 85 adults with schizophrenia or schizoaffective disorder took either luteolin or a placebo. The goal was to see if luteolin reduces overall sympt…
Phase: NA • Sponsor: University of Maryland, Baltimore • Aim: Symptom relief
Last updated Apr 30, 2026 15:48 UTC
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New app aims to ease cancer Survivors' recovery
Symptom relief CompletedThis study tested a smartphone app called POSTHOC that helps cancer survivors track symptoms and health goals after finishing treatment. 51 adults who recently completed cancer therapy used the app or received standard care for 12 weeks. The goal was to see if the app makes it ea…
Phase: PHASE1, PHASE2 • Sponsor: University of Maryland, Baltimore • Aim: Symptom relief
Last updated Apr 29, 2026 15:15 UTC
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Can a sleep pill boost your daytime brain power? new study says maybe
Symptom relief CompletedThis study looked at whether suvorexant, an FDA-approved sleep aid, can improve daytime symptoms like thinking, mood, and energy in older adults with insomnia. Forty participants took either the drug or a placebo and reported their symptoms on a smartphone. The goal was to see if…
Phase: PHASE2 • Sponsor: University of Maryland, Baltimore • Aim: Symptom relief
Last updated Apr 26, 2026 20:00 UTC
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Veterans study: can shedding pounds and walking more cool down body inflammation?
Knowledge-focused CompletedThis study looked at how age and body fat affect inflammation in 100 veterans. Researchers wanted to see if losing a moderate amount of weight and increasing aerobic exercise could lower inflammation. Participants followed a weight loss and exercise program to measure changes in …
Phase: NA • Sponsor: University of Maryland, Baltimore • Aim: Knowledge-focused
Last updated May 01, 2026 16:01 UTC
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Breathing new life: training program for childhood cancer survivors
Knowledge-focused CompletedThis study looked at whether a 6-week breathing muscle training program is possible for childhood cancer survivors and how it affects their breathing during exercise. Seven survivors who finished cancer treatment at least a year ago took part. The goal was to see if they could st…
Phase: NA • Sponsor: University of Maryland, Baltimore • Aim: Knowledge-focused
Last updated May 01, 2026 15:59 UTC
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Brain zaps reveal clues in schizophrenia
Knowledge-focused CompletedThis study looked at how a non-invasive brain stimulation technique called TMS changes brain activity in people with schizophrenia. Ten participants received both real and fake TMS sessions, and researchers measured brain connectivity and electrical signals before and after. The …
Phase: NA • Sponsor: University of Maryland, Baltimore • Aim: Knowledge-focused
Last updated May 01, 2026 15:58 UTC
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Brain chemistry study seeks to understand schizophrenia better
Knowledge-focused CompletedThis study looked at how a supplement called N-acetylcysteine (NAC) affects brain chemicals and thinking in people with schizophrenia. Researchers gave participants tryptophan (an amino acid) to raise a brain chemical called kynurenic acid, then used cognitive tests and MRI scans…
Phase: PHASE1, PHASE2 • Sponsor: University of Maryland, Baltimore • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:52 UTC
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Epinephrine's hidden role in blood vessel health revealed
Knowledge-focused CompletedThis study looked at how epinephrine, a key hormone that fights low blood sugar, affects blood vessel function and clotting in 32 healthy adults aged 18-55. Researchers measured changes in artery dilation before and after giving epinephrine. The goal was to better understand diab…
Phase: EARLY_PHASE1 • Sponsor: University of Maryland, Baltimore • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:51 UTC
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Seeing is believing: how observing others eases your pain
Knowledge-focused CompletedThis study looked at how watching someone else experience pain relief can actually reduce your own pain. Researchers used brain scans to see which parts of the brain are involved in this 'observational learning' effect. 211 healthy adults participated, and the goal was to underst…
Phase: PHASE2 • Sponsor: University of Maryland, Baltimore • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:15 UTC
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Can a workplace wellness program boost heart health for caregivers?
Knowledge-focused CompletedThis study tested a workplace wellness program designed to reduce stress and improve heart health in long-term care workers. 159 staff and residents participated. The program aimed to help staff adopt healthier habits, which might also positively influence the residents they care…
Phase: NA • Sponsor: University of Maryland, Baltimore • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:05 UTC
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New lab report strategy cuts unnecessary antibiotics in ICU patients
Knowledge-focused CompletedThis study tested a new way of reporting lab results for patients on breathing machines who might have pneumonia. The goal was to see if changing how the lab reports test results could help doctors avoid prescribing antibiotics that aren't needed. The study included 161 adults in…
Phase: NA • Sponsor: University of Maryland, Baltimore • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:04 UTC
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ER bed blocking: new study reveals hidden costs of hospital delays
Knowledge-focused CompletedThis study looked at over 30,000 adults admitted to hospitals in Maryland to understand why some patients wait in the emergency room even after being admitted (called boarding). Researchers measured how long patients boarded, what it cost, and how it affected care for all ER pati…
Sponsor: University of Maryland, Baltimore • Aim: Knowledge-focused
Last updated Apr 26, 2026 20:03 UTC