University Of Maryland, Baltimore
Clinical trials sponsored by University Of Maryland, Baltimore, explained in plain language.
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Cancer drug tested against COVID-19 in small trial
Disease control TerminatedThis study tested whether imatinib, a drug used for certain cancers, could help hospitalized adults with COVID-19. Participants received either imatinib or a placebo alongside standard care. The trial was stopped early and only included 21 people, so no firm conclusions can be dr…
Phase: PHASE3 • Sponsor: University of Maryland, Baltimore • Aim: Disease control
Last updated Jun 22, 2026 12:03 UTC
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Nerve repair supplement fails to reach finish line in diabetes study
Disease control TerminatedThis study tested whether a supplement called nicotinamide riboside (NR) could help repair nerve damage in people with type 2 diabetes or prediabetes. The goal was to see if NR could increase nerve fiber density in the skin, a sign of healthier nerves. The study was stopped early…
Phase: PHASE1, PHASE2 • Sponsor: University of Maryland, Baltimore • Aim: Disease control
Last updated Jun 18, 2026 11:53 UTC
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Can freezing the body buy time to fix fatal bleeding?
Disease control TerminatedThis study tested a way to rapidly cool people who had a cardiac arrest from severe bleeding after a traumatic injury. The idea was to flush ice-cold salt water into the body to preserve the brain and organs, giving surgeons time to stop the bleeding before slowly rewarming the p…
Phase: PHASE2 • Sponsor: University of Maryland, Baltimore • Aim: Disease control
Last updated Jun 18, 2026 11:49 UTC
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Brain bleed drug combo study halted after just one patient
Disease control TerminatedThis study looked at whether adding the drug pioglitazone to a keyhole brain surgery (MIPS) could help people recover from a severe bleeding stroke. Only one person took part before the study was stopped early. The goal was to see if the combination was safe and helped clear the …
Phase: PHASE2 • Sponsor: University of Maryland, Baltimore • Aim: Disease control
Last updated Jun 17, 2026 12:05 UTC
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Gum treatment may shield aging brains from dementia
Prevention TerminatedThis study looked at whether intensive treatment for gum disease (periodontitis) could slow cognitive decline in older adults with mild memory problems and narrowed neck arteries. Researchers compared intensive gum therapy to standard care in 26 participants aged 65 and older. Th…
Phase: NA • Sponsor: University of Maryland, Baltimore • Aim: Prevention
Last updated Jun 15, 2026 19:08 UTC
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Walking and eating tips may ease chemo nerve pain
Symptom relief TerminatedThis study tested whether a 12-week home exercise program or nutrition education could reduce nerve damage caused by platinum chemotherapy in people with gastrointestinal cancers. The trial was small and terminated early, so findings are preliminary. The goal was to gather data f…
Phase: PHASE2 • Sponsor: University of Maryland, Baltimore • Aim: Symptom relief
Last updated Jun 22, 2026 11:56 UTC
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Weight and breast cancer drugs: does size matter?
Knowledge-focused TerminatedThis study looked at whether postmenopausal women with higher body fat respond differently to standard doses of aromatase inhibitors (anastrozole or letrozole) compared to women with lower body fat. The goal was to see if weight affects how well these hormone-blocking pills shrin…
Phase: NA • Sponsor: University of Maryland, Baltimore • Aim: Knowledge-focused
Last updated Jun 15, 2026 18:54 UTC