University Of Maryland, Baltimore
Clinical trials sponsored by University Of Maryland, Baltimore, explained in plain language.
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Cancer drug fails to prove benefit in small COVID-19 trial
Disease control TerminatedThis study tested whether the cancer drug imatinib could help hospitalized adults with COVID-19. It was a Phase 3 trial that planned to compare imatinib plus standard care against a placebo plus standard care. The main goal was to see if imatinib reduced deaths by day 28. However…
Phase: PHASE3 • Sponsor: University of Maryland, Baltimore • Aim: Disease control
Last updated May 01, 2026 16:00 UTC
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Stroke clot removal study with diabetes drug shutters after enrolling just one patient
Disease control TerminatedThis study aimed to see if adding the diabetes drug pioglitazone to a minimally invasive brain surgery could improve recovery after a severe type of stroke called intracerebral hemorrhage. The plan was to enroll 20 adults aged 18-80 with a specific type of brain bleed, but the st…
Phase: PHASE2 • Sponsor: University of Maryland, Baltimore • Aim: Disease control
Last updated Apr 30, 2026 15:55 UTC
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Can Ice-Cold saline buy time to fix bleeding in trauma arrest?
Disease control TerminatedThis study tested a way to quickly cool down trauma victims whose hearts stopped from severe bleeding. Doctors flushed ice-cold salt water into the body to slow damage, then used a heart-lung machine to restart blood flow after surgery. The goal was to see if people could survive…
Phase: PHASE2 • Sponsor: University of Maryland, Baltimore • Aim: Disease control
Last updated Apr 29, 2026 15:04 UTC
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Exercise and nutrition may ease chemo nerve damage
Symptom relief TerminatedThis study tested whether exercise or nutrition education can reduce nerve pain caused by platinum chemotherapy in people with gastrointestinal cancers. 36 participants were enrolled. The goal was to see if these approaches improve symptoms and help design a larger future study.
Phase: PHASE2 • Sponsor: University of Maryland, Baltimore • Aim: Symptom relief
Last updated Apr 26, 2026 20:00 UTC
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Weight may affect how breast cancer drugs work, study suggests
Knowledge-focused TerminatedThis study aimed to find out if standard doses of aromatase inhibitors (hormone-blocking pills) work differently in overweight or obese postmenopausal women with early breast cancer compared to normal-weight women. About 42 women were planned to take anastrozole or letrozole befo…
Phase: NA • Sponsor: University of Maryland, Baltimore • Aim: Knowledge-focused
Last updated May 01, 2026 15:59 UTC
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Gum treatment may shield aging brains from dementia
Knowledge-focused TerminatedThis study looked at whether intensive treatment for gum disease (periodontitis) could slow memory loss in older adults with mild cognitive impairment and narrowed neck arteries. Researchers planned to compare intensive gum therapy to standard care in 26 people aged 65 and older.…
Phase: NA • Sponsor: University of Maryland, Baltimore • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:50 UTC