University Of Edinburgh
Clinical trials sponsored by University Of Edinburgh, explained in plain language.
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Could a heart drug save lives from pesticide poisoning?
Disease control CompletedThis study looked at whether adding two widely available medicines (magnesium sulphate or nimodipine) to standard treatment could help people who intentionally poisoned themselves with certain insecticides. Over 1,700 adults were enrolled. The main goal was to see if these added …
Phase: PHASE3 • Sponsor: University of Edinburgh • Aim: Disease control
Last updated May 26, 2026 03:21 UTC
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Donor cells fight transplant-linked cancer in landmark trial
Disease control CompletedThis study tested whether specially treated donor white blood cells could help treat a rare cancer (lymphoproliferative disease) that sometimes happens after an organ transplant. The cancer is linked to the Epstein-Barr virus. 50 transplant recipients took part. The goal was to s…
Phase: PHASE3 • Sponsor: University of Edinburgh • Aim: Disease control
Last updated May 26, 2026 03:11 UTC
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Can a PET scan and blood thinner prevent silent heart attacks?
Disease control CompletedThis study looked at 220 people with coronary artery disease to see if a blood thinner called ticagrelor could reduce signs of heart muscle injury. Participants had a special PET scan to find high-risk plaques that might rupture without causing symptoms. The goal was to see if ti…
Phase: PHASE2, PHASE3 • Sponsor: University of Edinburgh • Aim: Disease control
Last updated May 26, 2026 03:10 UTC
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New drug combo shows promise for reducing fractures in brittle bone disease
Disease control CompletedThis study tested whether a two-year course of teriparatide (a bone-building drug) followed by a single infusion of zoledronic acid (a bone-strengthening drug) could reduce fractures in adults with osteogenesis imperfecta (OI), a genetic condition causing fragile bones. 350 adult…
Phase: PHASE4 • Sponsor: University of Edinburgh • Aim: Disease control
Last updated May 26, 2026 02:47 UTC
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Water workouts vs land exercises: which eases back pain best?
Symptom relief CompletedThis study looked at how water-based and land-based exercises affect chronic low back pain in adults aged 18 to 65. Over 12 weeks, 32 participants did supervised exercises in a pool or on land. Researchers measured pain, daily function, fear of movement, sleep, and quality of lif…
Phase: NA • Sponsor: University of Edinburgh • Aim: Symptom relief
Last updated May 26, 2026 03:15 UTC
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Borderline personality disorder empathy secrets revealed
Knowledge-focused CompletedThis study looked at how people with borderline personality disorder (BPD) understand and feel others' emotions. About 40 adults with BPD took computer tests and answered questionnaires over two years. The goal was to see if empathy changes with the severity of the disorder. No t…
Sponsor: University of Edinburgh • Aim: Knowledge-focused
Last updated May 26, 2026 03:21 UTC
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Heart attack drug dilemma: shorter may be safer
Knowledge-focused CompletedThis study looked at how long people who had a heart attack should take two blood-thinning medicines (aspirin plus a second drug). Over 5,000 patients were randomly assigned to shorter or longer treatment. The goal was to find the best balance between preventing another heart att…
Phase: PHASE4 • Sponsor: University of Edinburgh • Aim: Knowledge-focused
Last updated May 26, 2026 03:21 UTC
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Can a heart drug shield arteries from reperfusion injury?
Knowledge-focused CompletedThis study looked at whether rotigaptide, a drug that helps heart cells communicate, can protect blood vessel function after a temporary blockage of blood flow. Twelve healthy men participated. The goal was to see if the drug could reduce damage that sometimes happens when blood …
Phase: NA • Sponsor: University of Edinburgh • Aim: Knowledge-focused
Last updated May 26, 2026 03:15 UTC
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Can a high-tech insulin system and low-carb diet fix a dangerous diabetes complication?
Knowledge-focused CompletedThis study looked at 24 people with long-standing type 1 diabetes to see if using an automated insulin delivery system plus a low-carbohydrate diet for 8 months could restore their body's ability to release glucagon during low blood sugar (hypoglycemia). Glucagon is a hormone tha…
Phase: NA • Sponsor: University of Edinburgh • Aim: Knowledge-focused
Last updated May 26, 2026 03:13 UTC
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Scientists hunt for clues to stop cancer weight loss
Knowledge-focused CompletedThis study looked at why many cancer patients lose a lot of weight and muscle, a condition called cachexia. Researchers took samples of muscle, fat, blood, and urine from 282 patients during cancer surgery and compared them to samples from people without cancer. They also measure…
Sponsor: University of Edinburgh • Aim: Knowledge-focused
Last updated May 26, 2026 02:48 UTC
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New imaging sheds light on hidden clots after heart attacks
Knowledge-focused CompletedThis study looked at 100 people who recently had a heart attack to better understand blood clots in the heart and brain. Using special PET/MR scans, researchers tracked clot activity over time. The goal was to learn more about how clots form and dissolve, which could lead to bett…
Sponsor: University of Edinburgh • Aim: Knowledge-focused
Last updated May 22, 2026 13:51 UTC
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Probiotic study probes Gut-Brain link in Parkinson's
Knowledge-focused CompletedThis study looked at whether a probiotic called Bacillus subtilis can change certain markers in the gut and blood of people with Parkinson's disease. 26 participants took the probiotic or a placebo to see how it affected their gut bacteria, blood fats, inflammation, and other hea…
Phase: NA • Sponsor: University of Edinburgh • Aim: Knowledge-focused
Last updated May 18, 2026 12:12 UTC
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UK study maps rare nerve condition to improve care
Knowledge-focused CompletedThis study looked at 621 adults in the UK who had cauda equina syndrome, a rare condition where nerves at the bottom of the spine are squeezed. Researchers collected information on symptoms, treatments, and recovery to understand how the condition is managed and to help set bette…
Sponsor: University of Edinburgh • Aim: Knowledge-focused
Last updated May 14, 2026 12:02 UTC