University Hospital, Limoges

This study tests whether giving immunosuppressive drugs as a single daily dose after liver transplant works as well as the standard twice-daily regimen. About 162 liver transplant recipients will be randomly assigned to once-daily or twice-daily dosing. The goal is to see if once…

This study tests whether having nurses measure blood flow in tiny vessels (microcirculation) can help doctors start fluid treatment earlier for sepsis patients in the emergency room. About 556 adults with suspected sepsis will be enrolled. The goal is to see if this approach redu…

This study tests if a drug called interferon gamma can prevent new infections in ICU patients whose immune systems are weak. About 326 adults who have been in the ICU for at least a week will receive either the drug or a placebo. The goal is to see if the drug reduces infections …

This study tests a special home therapy program for people aged 75+ with dementia who were recently hospitalized for a fall. The program involves an occupational therapist who makes the home safer and trains a family caregiver to provide support. The goal is to see if this approa…

This study compares two drugs used during gallbladder surgery to see which one helps patients recover better with fewer side effects. One drug, sufentanil, is a common morphine-like painkiller that can cause nausea, confusion, and itching. The other, esmolol, is a heart medicatio…

This study is creating a large group of children with idiopathic nephrotic syndrome, a rare kidney disease, to follow their health over time. Researchers will collect information on relapses, treatments, and side effects. The goal is to better understand the disease and make it e…

This study looks at how filtering affects the helpful ingredients in serum eye drops for people with severe dry eye disease. Ten adults who haven't gotten better with standard treatments will provide blood samples to make the drops. The goal is to find the best way to prepare the…

This study is collecting information from 1,200 people in France who are having a special procedure called endoscopic submucosal dissection (ESD) to remove large colon polyps or early cancers. The goal is to see how well ESD works and how safe it is compared to older methods. Res…

This study looks at a kidney disease called IgA nephropathy, which can lead to kidney failure. Researchers want to find special markers in the blood that could help diagnose the disease without needing a kidney biopsy. They will study 150 adults who need a kidney biopsy as part o…

This study looks at genetic changes in natural killer (NK) and B cells from 140 people with chronic hepatitis B. Researchers want to understand why the immune system cannot clear the virus. Participants include both treated and untreated patients, as well as healthy volunteers. T…