University Hospital, Limoges

This study tested whether dobutamine, a heart-strengthening drug, could improve outcomes in people with septic shock and heart muscle weakness. 136 intensive care unit patients received either dobutamine or a placebo. The goal was to see if the drug reduced organ failure and impr…

This study looked at 156 adults with advanced non-small cell lung cancer whose first chemotherapy stopped working. It compared taking two drugs (erlotinib pills followed by docetaxel infusion) versus docetaxel alone. The goal was to see if the combo could delay cancer growth long…

This study looked at 134 kidney or liver transplant patients to see if switching from a twice-daily anti-rejection drug (Prograf) to a once-daily version (Envarsus) keeps drug levels stable. Researchers used blood tests and computer models to compare exposure. The goal is to make…

This study compares two procedures for removing large, flat colon polyps: endoscopic submucosal dissection (ESD) and endoscopic mucosal resection (EMR). The goal is to see which method leads to fewer polyps coming back and which is more cost-effective over time. About 360 adults …

This study tested whether a lab technique called flow cytometry can accurately diagnose allergies to muscle relaxant drugs used during anesthesia. Researchers enrolled 129 adults who had a suspected allergic reaction during a previous surgery. The goal was to see if the test coul…

This study tested whether chewing gum can help doctors diagnose giant cell arteritis (Horton's disease), a condition that causes inflamed blood vessels. Researchers asked 66 people—some with suspected disease and some healthy—to chew gum for 4 minutes to see if it triggered jaw p…

This study looked at two different pain management methods for people aged 70 and older who had a hip fracture and were waiting for surgery. The goal was to see which method worked better to reduce pain during washing before the operation. Forty patients took part, and the main f…

This study looked at whether adding a relaxing touch technique to standard pain treatment can lower pain when removing a surgical drain in children aged 7 to 17. About 232 children took part. The goal was to see if this drug-free method improves comfort and reduces pain scores.

This study tested a program where parents and children prepare together before surgery to see if it lowers children's anxiety when they go to sleep for the operation. Fifty children aged 5 to 12 having planned surgery took part. The program aimed to help parents support their chi…

This study tested whether adding a specific massage technique (manual lymphatic drainage) to standard physical therapy helps people regain knee movement faster after knee replacement surgery. About 44 adults who had knee replacement took part. The massage aims to reduce swelling …

This study looked at whether using an early heart ultrasound (echocardiography) in the emergency department can help guide treatment and reduce organ damage in adults with sepsis or septic shock. Researchers compared this approach to standard care based on current guidelines. The…

This study looked at whether home automation and remote monitoring can help elderly people (65+) with multiple chronic illnesses live independently. Over 500 participants had their homes equipped with sensors to track health signs and detect early warning signs of disease flare-u…

This study surveyed 121 adults with autoimmune diseases like lupus, Sjögren's syndrome, or scleroderma to find out how many use alternative medicines (such as herbal remedies or acupuncture). Participants filled out an anonymous questionnaire about their practices. The goal was s…

This study checked whether the tick-borne encephalitis virus (TBEV) is present in the Limousin region of France. Researchers tested blood samples from 878 people who had a positive Lyme test or symptoms of brain swelling. They also looked for the virus in spinal fluid when availa…

This study looked at how the antifungal drug micafungin behaves in critically ill ICU patients with invasive candidiasis, a serious fungal infection. Researchers measured drug levels in 60 patients to see if standard doses are enough or if personalized dosing is needed. The goal …

This study followed 400 stem cell transplant recipients to see how well anti-CMV medications work in everyday hospital care. Researchers tracked infections, drug resistance, and side effects. The goal was to improve treatment guidelines for these high-risk patients.

This study examined how the heart's ability to pump and relax affects survival in people with septic shock, a life-threatening infection that causes organ failure. Researchers followed 440 intensive care patients, measuring heart function with ultrasound and tracking daily fluid …

This study looked at how leg muscles activate when people who have had a stroke walk. Researchers tested 500 participants to see if current measurement methods are reliable and to find early signs that predict walking recovery. The goal is to use these insights to create better, …

This study looked at 30 people with scleroderma, an autoimmune disease that often affects the hands. Researchers measured how much each hand could move and compared the dominant hand to the other. The goal was to better understand hand disability and guide future therapy.

This study looked at how often people with primary Sjögren's syndrome have digestive issues. Researchers used a questionnaire to track 10 different digestive symptoms in 151 patients. The goal was to better understand these symptoms and how they relate to the disease.

This study tested if letting parents watch and help with syringe feeding (instead of using a machine) encourages them to spend more time in the neonatal unit. 72 premature babies born between 30-34 weeks took part. The goal was to see if this simple change increases parental pres…

This study looked at how doing a thinking task while walking affects the brain activity of stroke survivors. 11 people who had a stroke walked on a special mat while wearing a brain scanner. The goal was to understand why walking can become harder when you have to think at the sa…