University Hospital, Bordeaux

This study compares two ways to drain urine in men with blocked bladders before prostate surgery: self-catheterization (done by the patient several times a day) versus a permanent tube. The goal is to see if self-catheterization leads to fewer infections. About 106 men over 50 wi…

This study looks at a drug called imlifidase that temporarily removes harmful antibodies from the blood, allowing highly sensitized kidney patients to receive a transplant from a donor they would otherwise reject. About 450 adults who are unlikely to get a kidney through standard…

This study looks at two methods for detecting minimal residual disease (MRD) in acute myeloid leukemia (AML) patients after chemotherapy. One method relies on expert manual analysis, while the other uses a computer algorithm called FlowSOM. Researchers will compare results from 6…

This study looks at newborn boys with posterior urethral valves (PUV), a rare birth defect that raises the risk of serious kidney infections. It compares circumcision alone versus circumcision plus daily antibiotics to see if the surgery alone is enough to prevent these infection…

This study tests whether having general practitioners hand out colorectal cancer screening kits directly to eligible patients (ages 50-74) during visits increases screening rates compared to the usual method of mailing an invitation to make an appointment. About 26,260 people wil…

This study will collect blood and tumor samples from 45 adults with glioblastoma, a serious brain cancer, to understand why it often returns after treatment. Researchers will look at molecular, immune, and metabolic changes in the samples. The goal is to find new ways to target t…

This study will follow 50 adults and children who are starting long-term parenteral nutrition (IV nutrition) to measure the buildup of advanced glycation end-products (AGEs) in their skin. AGEs are harmful compounds that form when sugar binds to proteins, and they may increase he…

This study looks back at medical records of 300 adults in France who had a rare but life-threatening fungal infection in a blood vessel graft. Researchers want to learn what treatments work best and what affects survival. No new treatments are being tested; the goal is to gather …

This study looks at why some people with Common Variable Immunodeficiency (CVID) develop complications not caused by infections. Researchers will test whether a type of immune cell called peripheral helper T-cells (Tph) helps faulty B-cells produce antibodies that lead to these c…

This study will collect tumor samples and medical data from 150 adults with non-small cell lung cancer (stages I to IV) at Bordeaux University Hospital. Researchers will analyze the molecular, metabolic, and immune features of the tumors to understand how the cancer progresses an…

This study will test a new, non-invasive ultrasound technique that captures brain blood flow in real time for infants with congenital heart disease. Researchers aim to understand how medical treatments and surgeries affect the brain, potentially explaining why some children later…

This study tests a new way to detect if a coma patient is aware but unable to move, known as cognitive-motor dissociation. Researchers will use EEG to measure brain activity after a mild wrist nerve stimulation, looking for signs of motor intention. The goal is to improve predict…

This study aims to find out how often a rare genetic condition called alpha-1 antitrypsin deficiency (AATD) occurs in people who develop liver cancer (hepatocellular carcinoma) but do not have cirrhosis or other known causes like hepatitis or heavy drinking. Researchers will look…

This study looks at how social and psychological factors, like beliefs and emotions, relate to spine posture in 150 adults with healthy spines. Participants fill out questionnaires and have a special X-ray to measure their spine alignment. The goal is to understand these connecti…

This study looks at why people with Noonan syndrome often bleed easily, especially from the skin, mouth, or nose. Researchers will compare a simple questionnaire about bleeding history with blood tests in 100 patients. The goal is to find better ways to predict serious bleeding, …

This study examines how much the tensor fascia latae muscle is damaged during hip replacement surgery through the front approach. Researchers will compare the amount of muscle damage to how well patients recover at 6 weeks and 6 months. The goal is to understand if less muscle da…

This study follows 4200 mothers and their children for 5 years to see if inducing labor at 39 weeks (instead of waiting for natural labor) affects the child's brain development. Researchers will assess thinking, language, movement, and behavior skills. The goal is to help pregnan…

This study looks back at 400 adults in France who had a rare but serious blood vessel infection caused by the bacteria Coxiella burnetii. The goal is to learn why some patients die within two years and how to diagnose the infection faster. Researchers will review medical records …

This study tests a new DNA sequencing method that reads long stretches of DNA to find hidden genetic changes causing rare diseases like albinism and intellectual disability. Researchers will analyze stored blood or DNA from 150 patients who haven't gotten a clear diagnosis yet. T…

This study looks at whether a special nurse consultation before stroke patients go home helps them stick to their medications and care plan. About 300 adults who had a mild stroke and are returning home will take part. Half will get the extra nurse talk; the other half will get u…

This study looks at whether young people (ages 8–25) with chronic immune thrombocytopenic purpura (ITP) have lower aerobic fitness than healthy peers. Fatigue is a major problem for many with ITP, and the researchers want to see if it's linked to a 'vicious cycle' of being less a…

This study looks at whether a video call (teleconsultation) works as well as an in-person visit for checking pregnant patients before they receive anesthesia during delivery. About 250 first-time mothers will take part, and researchers will compare how complete and accurate the i…

This study aims to create a computer model, or 'digital twin,' of a person's heart to better predict who is at risk for sudden cardiac death after a first heart attack. Researchers will enroll 1000 people who have had a heart attack and track them for two years. The goal is to se…

This study looks at stored liver biopsy samples from 30 people with MASH (a fatty liver disease) to see if a protein test can predict who will develop liver cancer within 15 years. Half of the participants later got liver cancer, and half did not. Researchers will compare the pro…