University Hospital, Bordeaux

This study compared two antiplatelet drug regimens after transcatheter aortic valve implantation (TAVI) for aortic stenosis. One group received ticagrelor alone, the other received aspirin plus clopidogrel. The goal was to see which caused fewer serious complications like bleedin…

This study tested a special bone graft material (MatriBONE mixed with the patient's own bone marrow) for spinal fusion surgery in people with painful degenerative back problems. The goal was to see how well the bones fused together after 12 months. However, the trial was stopped …

This study tested whether adding cognitive remediation therapy and emotional skills training to standard obesity treatment could reduce food cravings and improve weight management. It involved 144 obese adults who reported food cravings. The program included weekly group sessions…

This study tested whether adding the immunotherapy drug avelumab to standard chemotherapy (gemcitabine and cisplatin) works better than chemotherapy alone for people with advanced bladder cancer. The trial planned to enroll 65 patients but was terminated early, so we have limited…

This study tested if the beta-blocker propranolol could control the growth of infantile hemangiomas (non-dangerous blood vessel growths) in babies under 4 months old. The trial was terminated early and only enrolled 14 infants. The goal was to measure changes in hemangioma thickn…

This early-phase trial tested whether low doses of interleukin-2 (IL-2) could boost certain immune cells (CD8+ regulatory T cells) in patients with warm autoimmune hemolytic anemia that did not respond to standard steroids. Only 2 adults were enrolled before the study was termina…

This study tested a special cement that mimics natural bone to repair broken vertebrae in adults aged 18 to 65. The cement is designed to be absorbed by the body and replaced with new bone over time. Only 4 people took part before the study was stopped early. The goal was to see …

This early-phase study looked at whether the drug lenalidomide is safe to give after a stem cell transplant for multiple myeloma that has come back. It included 13 adults aged 18 to 65 whose cancer had responded to previous treatment. The goal was to see how many people had serio…

This study tested a new imaging method to detect inflammation in fatty plaques that cause strokes. It involved 3 men who had a recent stroke and were scheduled for surgery to remove a plaque in their neck artery. The goal was to see if a special PET scan tracer could highlight in…

This study looked at whether eating corn rich in zeaxanthin (a natural pigment) could increase the density of the macular pigment in the eye, which may help prevent age-related macular degeneration (AMD), a leading cause of blindness. Nine healthy volunteers aged 20-35 ate a dail…

This study tested a nasal spray containing a strong painkiller (sufentanil) for adults with sickle cell disease experiencing a painful crisis. The goal was to see if it could provide faster relief than the standard gas mixture (EMONO) before giving morphine through an IV. The tri…

This study looked at whether giving vitamin C to hospitalized adults aged 75 and older with pneumonia could improve their breathing and daily function. Only 9 people took part before the study was stopped early. The goal was to see if vitamin C, which supports the immune system, …

This study collected blood, urine, stool, and respiratory samples from 615 COVID-19 patients and caregivers at Bordeaux University Hospital. The goal was to build a biobank for research on the virus and disease. The study was terminated early, but the samples may still help scien…

This study aimed to find out how common sperm problems are in men with Fabry disease. Researchers planned to check sperm samples from 22 men aged 18 to 65. The study was stopped early, so results are limited.

This study looked for hidden brain damage in 38 hospitalized COVID-19 patients. Instead of using standard MRI scans, researchers used electrical tests to check how well the brainstem was working. The goal was to find subtle nervous system problems that might not show up on regula…

This study looked at whether MRI scans can detect changes in the lungs of people with cystic fibrosis as well as CT scans do. CT scans use radiation, so finding a reliable alternative like MRI could mean safer monitoring over time. The study included 212 patients aged 8 and older…

This study tested special shoe insoles with pressure sensors to see if they can accurately measure walking speed and step patterns in people with CIDP, a nerve condition that causes walking difficulties. Researchers compared the insoles to a standard electronic walkway. The goal …