Heart drug may tame baby blood vessel growth
NCT ID NCT00744185
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested if the beta-blocker propranolol could control the growth of infantile hemangiomas (non-dangerous blood vessel growths) in babies under 4 months old. The trial was terminated early and only enrolled 14 infants. The goal was to measure changes in hemangioma thickness after one month of treatment compared to a placebo.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 2/3
Runs two stages together: whether the treatment works, then large-scale confirmation.
- Participants
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14 people
The number who actually took part.
- Start date
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Oct 2008
- Finished
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Apr 2010
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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Up to 4 months
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Infant aged less than 4 months * Infant with one or more hemangiomas sized more than 1 cm diameter * Infant not threatening for vital or functional structure and for which no treatment would be proposed * Informed consent * Patient with social insurance. Exclusion Criteria: * Alarming hemangioma (s) (complicated forms or localization at risk) * Cardiac pathology (cardiac malformation, heart failure, cardiac arrhythmias, pulmonary hypertension) * Asthma * Bronchopulmonary dysplasia * Bronchiolitis * Raynaud syndrome * Phéochromocytoma * Development of serious form of hemangioma (bleeding, necrosis, ulceration, infection, respiratory distress) requiring standard treatment
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Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Dermatologie Pédiatrique
Bordeaux, 33 076, France