University Hospital, Bordeaux

This study tests whether a special physiotherapy program can help prevent breathing failure in ICU patients after their breathing tube is removed. It compares this combined breathing and movement therapy to standard care in 256 high-risk patients. The goal is to see if this appro…

This study is testing whether a computer system (AI) can help doctors spot more dangerous growths during a routine colonoscopy. About 600 people getting a screening colonoscopy will be randomly assigned to have it done with or without the AI assistant. The main goal is to see if …

This study tests a new three-part strategy to make placing emergency breathing tubes safer for critically ill adults. It combines a specific muscle relaxant, brief assisted breathing before tube placement, and a special guiding tool. The goal is to reduce serious complications li…

This study aims to validate a simple, non-invasive ultrasound test to help doctors decide which critically ill children on breathing machines need IV fluids. The test measures changes in blood flow in the heart to predict if a child will respond to fluids, helping avoid giving un…

This study is testing a new type of imaging scan to see if it can better detect infections on artificial heart valves. Researchers will compare the new scan to the current standard scan in 40 adults who are suspected of having such an infection. The goal is to see if the new meth…

This study is testing if a quick, non-invasive eye exam called capillaroscopy can help doctors diagnose the cause of a scarring lung disease faster. Researchers will give the exam to 48 adults newly diagnosed with interstitial lung disease. The goal is to see if this test helps i…

This study is testing a new, very fast type of ultrasound imaging to better measure how well the heart fills with blood in children born with heart defects. It aims to see if this technology can more accurately assess heart stiffness and blood flow, which are hard to measure with…

This study aims to develop a better diagnostic tool for a specific type of adrenal gland tumor. Researchers will use a detailed blood test that measures many hormones at once, combined with basic health information like weight and blood sugar. They will use this data to create a …

This study aims to see if measuring a protein called P2X4 on certain blood cells can serve as a reliable marker for diagnosing Amyotrophic Lateral Sclerosis (ALS). Researchers will compare blood samples from 50 people with ALS to samples from healthy volunteers to see if P2X4 lev…

This study is testing a new way to diagnose a hard-to-detect bile duct cancer called cholangiocarcinoma. Researchers will analyze proteins in patients' bile fluid to see if this 'liquid biopsy' can provide a faster, more accurate diagnosis than current methods. The goal is to hel…

This study aims to develop and validate a new blood test for pregnant women that can determine the paternity of their baby. The test analyzes tiny bits of the baby's DNA found in the mother's blood, offering a non-invasive alternative to riskier procedures. The research is specif…

This study is testing whether a specific lab test that looks for antibodies against a person's own platelets can help doctors diagnose immune thrombocytopenia (ITP) faster and more accurately. It will enroll 225 adults who have been found to have low platelet counts. The goal is …

This study aims to find better ways to predict which pregnant women will develop gestational diabetes and have babies with high birth weight (macrosomia). Researchers will test 800 pregnant women using new markers (skin autofluorescence and glycated albumin) and compare them to t…

This study aims to see if starting hormone replacement therapy (HRT) improves the quality of sexual life for women with premature ovarian failure (early menopause). Researchers will follow 135 women, asking them to complete questionnaires about their sexual function and overall q…

This study is testing whether a brief hypnosis session can help anxious patients stay calmer and more still during a heart MRI scan. The goal is to see if reducing anxiety leads to clearer, more usable images, which could help doctors make faster diagnoses. Researchers will compa…

This study aims to understand how small blood vessel disease in the brain affects thinking and memory. Researchers will measure brain wave patterns in 80 older adults and see if personalized brain training or gentle electrical stimulation can improve these patterns. The goal is t…

This study aims to determine how reliable a standard medical test for daytime sleepiness is when repeated. Researchers will enroll 100 participants, including people with sleep apnea or narcolepsy and healthy volunteers. The goal is to see if this test consistently measures sleep…

This study aims to understand how systemic sclerosis (scleroderma), a rare and serious autoimmune disease, naturally changes over time. Researchers will follow 500 adult patients for five years, collecting health data and biological samples. The goal is to build a detailed pictur…

This study aims to understand if and why the immune system ages faster in people with lupus (SLE). Researchers will compare blood samples from 50 lupus patients to healthy individuals to look for signs of accelerated immune aging. The goal is to gather knowledge, not to test a ne…

This study aims to find a simple blood marker that can predict which children will truly benefit from receiving extra fluids after heart surgery. Currently, doctors give fluids to treat low blood pressure, but too much fluid can be harmful. The research will test if a specific bl…

This study aims to translate and validate a French version of the Sleep Regularity Questionnaire, a tool that measures how consistent people's sleep patterns are. Researchers will enroll 50 French-speaking adults who are already scheduled for sleep monitoring due to chronic insom…

This study aims to find out if specific markers in the blood can predict which patients with certain blood cancers are most likely to develop dangerous blood clots. Researchers will follow 300 patients for two years, taking blood samples to measure these markers. The goal is to b…

This study looks back at medical records to understand if starting kidney dialysis early or waiting longer is better for cancer patients who develop tumor lysis syndrome, a serious complication that can damage kidneys. Researchers will compare 800 patients treated in French inten…

This study aims to understand why people with diabetic foot ulcers have a higher risk of death and other serious health problems. Researchers will follow 1,000 patients in France for five years to track their health, quality of life, and medical costs. The goal is to identify the…

This study aims to understand if multiple sclerosis (MS) affects a woman's ovarian reserve, which is linked to fertility. It will compare 160 women with MS to a group of healthy women, all aged 25-35. Researchers will measure hormone levels and perform ultrasounds to see if there…

This research study aims to understand how specific immune cells contribute to different forms of multiple sclerosis (MS). Researchers will analyze blood and spinal fluid samples from 150 adults with MS or early symptoms to identify which cell types are most involved in the disea…

This study aims to learn if a special imaging technique can help doctors better adjust ventilator settings for patients with severe lung failure (ARDS). Researchers will use the imaging to see how different air pressure levels affect the lungs when patients are lying on their bac…

This study aims to understand how stem cell transplants for acute leukemia affect women's reproductive health. Researchers will review medical records of 80 women who received transplants as adults to document gynecological complications like early menopause and fertility issues.…

This study aims to understand the brain basis of Restless Legs Syndrome (RLS). Researchers will compare brain scans and daily symptom tracking from 30 people with RLS to 30 healthy volunteers. The goal is to see if changes in how the brain processes internal body signals are link…

This study aims to understand how harmful blood clots form in the smallest blood vessels of patients with severe sepsis (septic shock) who need kidney dialysis. Researchers will compare two different types of dialysis filters to see if one affects the levels of substances linked …

This study aims to understand how mitochondrial diseases affect the immune system. Researchers will analyze blood samples from 60 participants (30 patients and 30 healthy volunteers) to measure immune cell levels and function. The goal is to identify immune problems that could ex…

This study aims to better understand systemic granulomatosis, a group of inflammatory diseases like sarcoidosis. Researchers will follow 150 patients at a single hospital for up to 10 years to track how their disease changes over time. The main goal is to collect detailed health …

This study aims to understand how often depression and malnutrition occur in patients who develop infections after orthopedic surgery. Researchers will follow 300 patients for three years to track their mental health, nutrition, and recovery. The goal is to gather information tha…

This study aims to understand the current state of gynecological care for transgender people in France. Researchers will survey 500 transgender adults to learn about their actual care, their knowledge of recommended screenings, and the impact of hormone therapy. The goal is to ga…

This study is testing new MRI scanning techniques on healthy volunteers to see if they can produce clearer images faster. Researchers want to develop better scanning methods that could help doctors diagnose diseases more accurately in the future. The study involves 200 healthy ad…

This study aims to see if using a smartphone app to track symptoms in real-time is a practical way to understand Restless Legs Syndrome (RLS). For two weeks, 62 adults with RLS will carry a study phone and a wrist-worn activity monitor to log their symptoms, activities, and mood.…

This study is testing whether using filtered, reusable water is safe for colonoscopies. Currently, sterile water in single-use bottles is used, which creates waste. Researchers want to see if reusable water bottles can be used without getting contaminated during the procedure, an…

This study is creating a large national database to collect detailed information from 30,000 kidney cancer patients in France. The goal is to gather real-world data on treatments, outcomes, and patient experiences to help researchers better understand the disease. It does not tes…