The Hospital For Sick Children

This study is testing whether following a Mediterranean-style diet for 8-12 weeks can help improve arthritis symptoms in children. Researchers want to see if the diet works by changing the mix of bacteria in the gut. The study will enroll 54 children with arthritis to see if this…

This study is testing whether deep brain stimulation can reduce severe self-injurious behaviors in children with autism who haven't responded to other treatments. Researchers will implant small devices in the brains of 25 children to deliver electrical stimulation to specific are…

This early-stage study is testing whether metformin, a common diabetes medication, can help repair nerve damage in children and young adults with multiple sclerosis (MS). Researchers want to see if the drug can stimulate the brain's own repair cells to rebuild the protective coat…

This study is testing whether a computer program can help doctors identify children in the hospital with serious heart conditions who are at high risk of a major health event. The program predicts which patients might benefit from earlier conversations with a special support team…

This study is testing if a special type of MRI scan, where children hold their breath while inhaling a safe gas, can help doctors spot a serious lung condition earlier. The condition, called bronchiolitis obliterans syndrome, can happen after a child receives a stem cell transpla…

This study is testing two new types of MRI scans that use safe, inhaled gases instead of radiation to create detailed pictures of the lungs. Researchers want to see if these scans can detect changes in lung structure and function in people with cystic fibrosis or asthma more clea…

This study tests whether a computer model can predict which children in the hospital for cancer treatment are most likely to vomit in the next four days. If the model flags a child as high-risk, pharmacists will alert the medical team so they can start preventive anti-nausea medi…

This study is testing if adding a drug called olanzapine to standard anti-nausea medicines can better control vomiting in children receiving very strong chemotherapy for cancer or before a stem cell transplant. It will involve about 200 children and teenagers. The main goal is to…

This study aims to find out exactly how much of four essential building blocks (amino acids) stable, premature babies need when they are fed entirely through an IV. Researchers in Brazil will measure how babies' bodies use these nutrients by analyzing their breath and urine. The …

This study is testing whether a computer model can help doctors identify children in the hospital who are likely to need certain medications soon, so that genetic testing can be offered in advance. The goal is to see if this timely testing leads to more personalized medication ch…

This study aims to better understand how common respiratory viruses like the flu, RSV, and COVID-19 spread among children. Researchers will track 500 children under 18 who test positive for one of these viruses, along with their household and classroom contacts. The goal is to le…