Technical University Of Munich

This study tests whether giving ICU patients extra protein and activating their muscles early with electrical stimulation can prevent severe muscle loss. About 40 critically ill adults on breathing machines will take part. The goal is to see if this approach helps patients keep m…

This study looks at two ways to treat a specific type of neck fracture (odontoid fracture) in people aged 70 and older. One group will have surgery to fix the bones, while the other group will wear a rigid neck brace for several weeks. The goal is to see which treatment helps pat…

This study tests whether a gentle, at-home brain stimulation device (tDCS) can help people with depression maintain their improvement after successful hospital treatments like rTMS, ECT, or esketamine. Thirty adults who have already improved will use the device for 30 minutes, 5 …

This study looks at whether a short-term whole-food, plant-based diet can change how the immune system works and affect disease activity in people with early-stage chronic lymphocytic leukemia (CLL) who have not yet had treatment. About 50 participants will follow the diet for 4 …

This study compares standard kidney stone surgery (using a scope and laser) to the same surgery plus a special hydrogel that captures tiny stone fragments. The goal is to see if the gel helps remove more stone pieces, which could lower the chance of stones coming back. About 120 …

This study tests whether giving the COVID-19 vaccine to babies as young as 6 months old can lower their chance of developing type 1 diabetes. It involves over 2,200 children who have a high genetic risk for the disease. Half will get the vaccine, half a placebo, and researchers w…

This study tests whether Blood Flow Restriction (BFR) training can reduce pain and improve elbow function in people with tennis elbow (lateral epicondylitis). About 40 adults who have had symptoms for more than 6 weeks but less than 12 months, and who have not improved with physi…

This study compares two recovery plans after hip replacement surgery: a standard approach and a 'fast track' approach designed to get patients home sooner. Researchers will measure how long patients stay in the hospital and how well they recover in terms of pain, movement, and qu…

This study looks at whether a heart procedure called ablation, combined with a 12-week exercise program, helps people with heart failure and atrial fibrillation use oxygen better. About 40 adults with both conditions will take part. The goal is to see if the combination improves …

This study tests whether fasudil, a drug already used in Japan for blood vessel spasms, is safe and can improve symptoms in people with early Parkinson's disease. 75 participants will receive either fasudil or a placebo twice daily for 3 weeks. The main goal is to check for side …

This study looks at whether the drug mavacamten can make it safe for people with a type of thickened heart muscle (hypertrophic obstructive cardiomyopathy) to do moderate exercise. About 24 adults already stable on mavacamten will either join a supervised 6-week exercise program …

This study looks at whether using an MRI scanner during brain surgery helps surgeons remove brain metastases more completely. About 154 adults who need surgery for brain tumors will take part. The goal is to see if this advanced imaging leads to better outcomes and fewer repeat p…

This study is for people with depression who are getting a treatment called TMS (transcranial magnetic stimulation), which uses magnetic pulses to stimulate the brain. Researchers will use MRI brain scans before, during, and after 20 TMS sessions to see how the brain changes and …

This study is testing a smartphone app that tracks movement and symptoms in people before and after knee or hip replacement surgery. The goal is to create a score that helps predict which patients will be satisfied with their surgery. About 1,250 adults in Germany will participat…

This study looks at whether exercising before or after breakfast or dinner changes how the body processes sugar from meals. Thirty healthy, active adults will try different exercise schedules while wearing a continuous glucose monitor. The goal is to understand the best timing fo…

This study tests whether a program that teaches married couples about money and healthy relationships can improve their bond and mental health. About 4,500 couples in three Indian states will take part. The program involves six sessions, and researchers will measure changes in re…

This study looks at why some patients become very weak after being in the intensive care unit (ICU). Researchers will take blood and small muscle samples from 20 high-risk surgical patients to find chemical markers linked to this weakness. The goal is to better understand the pro…

This study adds special sports tests to a larger knee replacement recovery study. Researchers want to see if these tests can help patients know when it's safe to return to activities like running or tennis. About 50 people who have had knee replacement and are active in sports wi…

This study tests whether using artificial intelligence to rewrite medical discharge letters in plain language helps cancer patients better understand their diagnosis, treatment, and next steps. About 150 adults with blood cancer or other cancers will be randomly assigned to recei…