Technical University Of Munich

This phase 2 trial tests whether glycerol phenylbutyrate (GPB) can slow corticobasal syndrome (CBS), a rare and fast-progressing brain disease. 32 adults with CBS will receive either GPB or a placebo for 26 weeks. The main goal is to see if GPB lowers levels of a nerve damage mar…

This study tested a 6-month exercise program for older adults living in retirement homes. The program included strength, balance, and endurance training twice a week. Researchers measured changes in mobility, balance, and quality of life in 404 participants. The goal was to see i…

This study looked at combining the drug abemaciclib with standard hormone therapy as a first treatment for women with metastatic breast cancer that has spread to organs or has a high tumor burden. The goal was to see how many patients' tumors shrank or disappeared. The study enro…

This study explores whether a heart ultrasound taken during exercise on a special bicycle can detect subtle heart changes in young people who finished cancer treatment months or years earlier. It aims to see if this test is practical and acceptable for survivors aged 10 to 25, an…

This phase 2 trial tests whether fasudil, a drug already used in Japan for blood vessel spasms, is safe and can help symptoms in people with early Parkinson's disease. 75 participants will take either fasudil or a placebo for 3 weeks. The study focuses on safety and tolerability,…

This study tested whether taking 4 grams of taurine every day for 6 months can slow biological aging in healthy adults aged 55 to 75. Researchers measured aging through blood and DNA tests, and also checked physical fitness and thinking skills. The goal was to see if this simple …

This study looked at how cancer patients, the general public, and healthcare professionals use and feel about large language models (like ChatGPT) for making cancer treatment decisions. Over 7,000 people from 30 countries completed a survey. The goal was to understand current usa…

This study looked at whether using regular CT scans (already done for other reasons) can better predict the risk of spine fractures in people over 50, compared to the standard FRAX risk score. Researchers analyzed CT images from nearly 2,800 adults taken five years apart. The goa…

This completed pilot study looked at how moderate exercise affects heart function and dangerous heart rhythms in 20 adults with arrhythmogenic cardiomyopathy (ACM). Participants did different types of exercise while doctors measured heart pressures and electrical activity. The go…

This study looked at how a low-carb diet or a standard calorie-restricted diet affects metabolic flexibility—the body's ability to switch between using carbs and fat for energy. Thirty healthy adults followed each diet for two weeks. Researchers measured breath ketones, blood sug…

This study looked at whether exercising in the morning or evening, without eating first, changes how many calories people eat right after and over the next 24 hours. Thirty-five healthy adults aged 18-30 completed fasted exercise sessions at different times. Researchers measured …

This study looked at how 6 weeks of endurance training changes brown and beige fat, which helps the body burn sugar and fat for heat. Twenty-four healthy adults were split into a training group and a control group. Researchers took blood and fat samples before and after to see ho…

This study looked at 108 healthy sports science students to see if past leg injuries leave lasting changes in walking and running patterns. Participants wore small sensors on their legs while walking and running, and filled out questionnaires about their injury history. The goal …

This study followed 277 male runners who took part in a 2009 study to see how years of ultra-endurance running affect the heart and body. Researchers measured heart function and blood markers over a decade. The goal is to learn about the long-term effects of extreme exercise on h…