Semmelweis University
Clinical trials sponsored by Semmelweis University, explained in plain language.
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Gum bone repair: PRF gel vs. enamel matrix in head-to-head trial
Disease control CompletedThis study tested two treatments for deep bone defects caused by gum disease: platelet-rich fibrin (PRF) gel and enamel matrix derivative (EMD). Twenty-six adults with advanced chronic periodontitis received one of the two treatments during surgery. Researchers measured gum attac…
Phase: PHASE4 • Sponsor: Semmelweis University • Aim: Disease control
Last updated May 26, 2026 05:26 UTC
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Digital device offers new way to treat jaw cysts
Disease control CompletedThis study tested a new way to treat odontogenic cysts (fluid-filled sacs in the jawbone) using a custom-made device created with digital technology. Fifteen patients had the device placed right after a small surgical opening to slowly shrink the cyst before final removal. The go…
Phase: NA • Sponsor: Semmelweis University • Aim: Disease control
Last updated Apr 26, 2026 19:38 UTC
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New dental technique may stop gum recession during braces
Prevention CompletedThis study tested a procedure called PAOO to prevent bone loss and gum recession in people getting braces. 20 adults with crowded teeth and thin jawbones participated. The procedure involved a small cut in the gum and adding bone graft material before braces were placed. The goal…
Phase: NA • Sponsor: Semmelweis University • Aim: Prevention
Last updated May 26, 2026 04:37 UTC
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Can simple exercises keep teen handball Players' shoulders safe?
Prevention CompletedThis study tested two shoulder injury prevention programs in 137 teenage handball players (ages 13-19) from a Hungarian academy. Over 18 weeks, players did exercises from either a Swedish or Norwegian program. Researchers measured shoulder function, control, and injury rates to s…
Phase: NA • Sponsor: Semmelweis University • Aim: Prevention
Last updated May 15, 2026 11:57 UTC
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Brain zaps could ease tough symptoms of schizophrenia
Symptom relief CompletedThis study tested a type of brain stimulation called theta-burst TMS to see if it can safely reduce negative symptoms (like lack of motivation) and improve thinking in people with schizophrenia. 76 adults with stable schizophrenia took part in a double-blind trial where some rece…
Phase: NA • Sponsor: Semmelweis University • Aim: Symptom relief
Last updated May 26, 2026 05:33 UTC
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Talking it out: group therapy shows promise for eczema sufferers
Symptom relief CompletedThis study looked at whether adding group psychotherapy to standard eczema care can improve symptoms in adults with moderate-to-severe atopic dermatitis (eczema). Thirty-two participants were split into three groups: standard care alone, standard care plus cognitive behavioral th…
Phase: NA • Sponsor: Semmelweis University • Aim: Symptom relief
Last updated May 26, 2026 05:23 UTC
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New program helps teens take control of chronic pain
Symptom relief CompletedThis study tested a program to help Hungarian teenagers (ages 12-18) with chronic pain become more active and manage their pain better. The program combined motivational interviewing and self-management techniques, delivered either in person or via video. The goal was to see whic…
Phase: NA • Sponsor: Semmelweis University • Aim: Symptom relief
Last updated May 26, 2026 04:36 UTC
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Virtual reality goggles ease pain and fear for teens facing chest surgery
Symptom relief CompletedThis study tested whether using virtual reality (VR) before and after surgery could help teenagers feel less anxious and have less pain. Fifty teens having chest surgery for a condition called pectus excavatum took part. The researchers measured anxiety with a standard questionna…
Phase: NA • Sponsor: Semmelweis University • Aim: Symptom relief
Last updated May 26, 2026 04:35 UTC
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New method helps seniors get off the floor safely
Symptom relief CompletedThis study tested a teaching method called backward chaining to help elderly nursing home residents learn how to get up from the floor safely. 26 residents aged 65 and older who could walk at least 6 meters took part. The goal was to improve their mobility, muscle strength, and c…
Phase: NA • Sponsor: Semmelweis University • Aim: Symptom relief
Last updated May 19, 2026 11:46 UTC
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Which marking method helps surgeons find lung nodules faster?
Knowledge-focused CompletedThis study tested two methods to mark small lung nodules before minimally invasive surgery: one using a dye delivered through a breathing tube, and another using a radioactive substance guided by CT scan. 66 adults with lung nodules took part. The goal was to see which method hel…
Phase: NA • Sponsor: Semmelweis University • Aim: Knowledge-focused
Last updated May 26, 2026 05:29 UTC
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Jaw widening study: surgery vs. non-surgical method compared
Knowledge-focused CompletedThis study looked at two methods to widen the upper jaw in adults: one with surgery and one without. About 50 adults took part, and their jaw changes were measured with 3D scans over 12 months. The goal was to see which method works better and lasts longer, helping dentists choos…
Phase: NA • Sponsor: Semmelweis University • Aim: Knowledge-focused
Last updated May 19, 2026 11:47 UTC