Fondazione Policlinico Universitario Agostino Gemelli Irccs
Clinical trials sponsored by Fondazione Policlinico Universitario Agostino Gemelli Irccs, explained in plain language.
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Poop pills may boost cancer fight: kidney study shows promise
Disease control CompletedThis study tested whether transferring gut bacteria from people who responded well to immunotherapy could help others with advanced kidney cancer. Fifty patients received either a fecal transplant or a placebo alongside their standard immunotherapy. The goal was to see if this ap…
Phase: PHASE1, PHASE2 • Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Disease control
Last updated May 26, 2026 03:29 UTC
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New monitor may prevent blood pressure crashes in C-Sections
Disease control CompletedThis study tested a non-invasive finger cuff monitor that predicts blood pressure drops during planned C-sections. 102 women were randomly assigned to either standard blood pressure checks or the new continuous monitor. The goal was to see if the monitor could reduce the amount a…
Phase: NA • Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Disease control
Last updated May 26, 2026 03:28 UTC
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New hope for stuffy noses: drug shrinks polyps in rare disease
Symptom relief CompletedThis study looked at whether mepolizumab 300 mg can improve sinus symptoms in 52 adults with EGPA (a rare inflammatory disease) and severe, hard-to-control nasal polyps. Researchers measured changes in polyp size, quality of life, and smell function over 12 months. The goal was t…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Symptom relief
Last updated May 26, 2026 03:27 UTC
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New program boosts HIV patient engagement and quality of life
Symptom relief CompletedThis study tested a training program for people living with HIV to help them become more active in managing their health. The program, led by psychologists, aimed to improve emotional and behavioral involvement in treatment, leading to better quality of life and well-being. 75 pa…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Symptom relief
Last updated May 26, 2026 03:26 UTC
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Spinal morphine may cut opioid use after hysterectomy
Symptom relief CompletedThis study looked at 670 women who had a hysterectomy to see if spinal morphine works better than IV morphine for pain control. The goal was to reduce pain and the need for opioids after surgery. Researchers measured pain scores and side effects in the first 48 hours.
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Symptom relief
Last updated May 26, 2026 03:24 UTC
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Virtual therapy helps kids with rare epilepsy do daily tasks
Symptom relief CompletedThis study tested whether remote occupational therapy could help children and teens with Dravet syndrome improve their daily living skills. Fourteen families participated in online therapy sessions using the CO-OP approach. The goal was to see if telehealth could make therapy mor…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Symptom relief
Last updated May 26, 2026 03:15 UTC
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Psoriasis patients prefer cream over foam in new study
Symptom relief CompletedThis study looked at whether people with mild-to-moderate psoriasis prefer using Wynzora cream compared to Enstilar foam they had used before. Thirty adults who had stopped Enstilar for at least 30 days tried Wynzora for 4 weeks. Researchers measured preference, satisfaction, how…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Symptom relief
Last updated May 22, 2026 13:53 UTC
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Leukemia Patients' hidden threat: fungal infections under microscope
Knowledge-focused CompletedThis study observed 150 adults with a specific type of leukemia (Ph-negative ALL) to see how many develop serious fungal infections during the first weeks of chemotherapy. Researchers tracked infection rates and related deaths. The goal was to better understand this risk, not to …
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated May 26, 2026 03:29 UTC
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Tailored breathing support may reduce lung injury in respiratory failure
Knowledge-focused CompletedThis study looked at 20 adults with acute hypoxemic respiratory failure (low oxygen levels) to see how different noninvasive breathing support methods affect lung function. Researchers compared standard CPAP and NIV with a personalized approach guided by the patient's breathing e…
Phase: NA • Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated May 26, 2026 03:29 UTC
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Robot platform could help predict and prevent falls in older adults
Knowledge-focused CompletedThis study reviewed data from 355 adults aged 20 to 95 who used a robotic platform called hunova® to assess their fall risk. The goal was to understand how well the platform works in a clinic setting to identify people at risk of falling. Falls are a major health issue, especiall…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated May 26, 2026 03:28 UTC
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Scientists probe Cannabis-Like brain chemicals to tame gut troubles
Knowledge-focused CompletedThis study looked at how drugs that interact with the body's natural cannabis-like system affect the movement of the colon. Researchers used colon tissue samples from 36 colorectal cancer patients to test these drugs in the lab. The goal was to understand how these drugs might he…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated May 26, 2026 03:25 UTC
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Helmet or facemask: which breathing aid wins for low oxygen?
Knowledge-focused CompletedThis study looked at whether a helmet or a facemask is better at helping people with acute low-oxygen respiratory failure breathe easier. Twenty adults were randomly assigned to try both methods. Researchers measured breathing effort and lung function to see which approach works …
Phase: NA • Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated May 26, 2026 03:23 UTC
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What do women really think about membrane sweeping? new study listens
Knowledge-focused CompletedThis study interviewed 20 women to understand their feelings and experiences with membrane sweeping, a common method to start labor. The goal was to learn what women go through, not to test a treatment. Results will help doctors better support women during labor induction.
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated May 26, 2026 03:17 UTC
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Robot vs. surgeon: which adrenal surgery is better?
Knowledge-focused CompletedThis study looked back at 316 patients who had one adrenal gland removed through keyhole surgery. It compared the standard laparoscopic method to a newer robot-assisted technique to see which was safer, more effective, and more cost-effective. The goal was to help doctors choose …
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated May 26, 2026 03:17 UTC
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Tiny implants, big smiles: new study tests slim tooth replacements
Knowledge-focused CompletedThis study tested narrow dental implants for people missing a single tooth in the front of the mouth, where there isn't much space or bone. 17 patients received the implants using computer-guided surgery. The goal was to see how much bone loss occurred around the implant and how …
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated May 26, 2026 03:04 UTC
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Hidden Gut-Brain disorders common in kids with IBD
Knowledge-focused CompletedThis study looked at 220 children with inflammatory bowel disease (IBD) that is in remission to see how many also have disorders of gut-brain interaction (DGBIs), such as irritable bowel syndrome (IBS). Researchers compared them to healthy children to find out if these gut-brain …
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated May 26, 2026 02:48 UTC
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Bubble test may help doctors place central lines faster during heart surgery
Knowledge-focused CompletedThis study tested a simple method to confirm the position of a central venous catheter (a large IV) during heart surgery. Doctors injected a saltwater solution to create tiny bubbles and used an ultrasound on the chest to see how long it took for the bubbles to reach the heart. T…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated May 26, 2026 02:47 UTC
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New imaging study aims to personalize prostate cancer treatment
Knowledge-focused CompletedThis study looked at 70 men with newly diagnosed intermediate or high-risk prostate cancer. Researchers used special PET scans and blood tests to see if they could better predict how aggressive the cancer is. The goal is to help doctors choose the most effective treatment for eac…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated May 22, 2026 14:05 UTC
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Spinal shot before robotic surgery may ease pain afterward
Knowledge-focused CompletedThis study looked back at the records of 100 women who had robotic hysterectomy to see if a spinal injection of morphine before surgery helped control pain afterward. Researchers measured pain scores using a simple scale. The goal was to find out if this type of pain relief impro…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated May 22, 2026 13:54 UTC
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10-Year study reveals hidden clues about artery disease
Knowledge-focused CompletedThis study looked at 320 people with atherosclerosis (hardening of the arteries) to see how genetic, biological, and imaging factors relate to the disease getting worse over 10 years. Researchers used ultrasound scans to track changes in the arteries of the legs and neck. The goa…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated May 22, 2026 13:53 UTC
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Hidden cancer cells force second surgery in thyroid patients
Knowledge-focused CompletedThis study looked at 314 adults with small, early-stage papillary thyroid cancer who were scheduled for a less extensive surgery (lobectomy). Doctors checked lymph nodes during the operation and found that many patients had hidden cancer spread, requiring a second surgery to remo…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated May 22, 2026 13:52 UTC
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Brain oxygen boost: new protocol may protect patients during surgery
Knowledge-focused CompletedThis study looked at 48 adults having major abdominal surgery to see if preventing low blood pressure helps keep the brain's oxygen levels stable. One group received standard care, while the other used a special monitoring system to avoid drops in blood pressure. The goal was to …
Phase: NA • Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated May 20, 2026 11:53 UTC
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Liver cancer drug combo tested in real-world cirrhosis patients
Knowledge-focused CompletedThis study looked at how well a combination of two drugs (Atezolizumab and Bevacizumab) works compared to standard pills (tyrosine kinase inhibitors) in 38 patients with liver cancer and cirrhosis. The goal was to see if the combo is safe and effective in everyday medical practic…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated May 19, 2026 11:48 UTC
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Heart surgery training: study tracks Residents' learning curve for better bypass outcomes
Knowledge-focused CompletedThis study looked at how many coronary bypass surgeries cardiac surgery residents need to perform to become skilled at using two imaging tools that check the quality of new blood vessel connections during surgery. 80 adult patients having bypass surgery took part. The goal is to …
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated May 08, 2026 12:00 UTC