Leukemia Patients' hidden threat: fungal infections under microscope
NCT ID NCT05750706
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study observed 150 adults with a specific type of leukemia (Ph-negative ALL) to see how many developed serious fungal infections during their first weeks of chemotherapy. Researchers tracked infection rates and deaths linked to these infections. The goal was to better understand this risk, not to test a new treatment.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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150 people
The number who actually took part.
- Started
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Jun 2022
- Finished
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Mar 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adult patients with B or T acute lymphoblastic leukemia Ph negative
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * diagnosis of acute lymphoblastic leukemia Ph negative * age more than 18 yo Exclusion Criteria: * diagnosis of acute lymphoblastic leukemia Ph positive * acute lymphoblastic leukemia relapsed/refractory * lymphoblastic lymphoma
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Fondazione Policlinico Universitario A. Gemelli IRCCS
Rome, 00168, Italy
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a Low-Dose antifungal shield vulnerable patients from deadly fungal infections?
- Can we make CAR-T cells last longer in leukemia?
- Can a safer dose of an old drug shield vulnerable children from deadly fungal infections?
- Blood test clues could make antifungal dosing safer for transplant patients
- Tiny study aims to Fine-Tune fungal drug dosing during plasma exchange
- New combo therapy aims to boost survival in adult leukemia