Baylor College Of Medicine

This study tested a new vaccine to prevent hookworm infection in 39 healthy adults who had never had hookworms. Participants received different vaccine formulas and were later exposed to hookworms in a controlled setting to see if the vaccine worked. The goal was to check safety …

This study tested a new vaccine (Sm-TSP-2) to protect against intestinal schistosomiasis, a parasitic worm infection common in parts of Africa. Healthy adults in Uganda received different doses of the vaccine, with or without an immune booster, to check safety and how well it tri…

This study tested a new treatment for people with HPV-related cancers that returned or didn't respond to standard care. Researchers took blood from 32 patients, grew special immune cells (HPVST cells) that target HPV-infected cancer cells, and gave them back to patients. The goal…

This study tested a new program called THRIVE for people with HIV who are not regularly seeing a doctor. The program helps them stay in HIV care after leaving the hospital. 75 adults took part, and the study looked at whether the program was acceptable and if it improved viral lo…

This early-phase study tested a new approach for people with advanced B-cell non-Hodgkin lymphoma or chronic lymphocytic leukemia (CLL) that had returned or not responded to standard treatments. Researchers took patients' own immune cells (T cells) and added a special receptor (a…

This early-phase study tested a new approach for children with high-risk neuroblastoma, a cancer that often returns. Researchers took the patients' own immune cells (T cells) and modified them to better recognize and attack the cancer, while also training them to last longer in t…

This early-phase study tested a chemotherapy regimen called dose-adjusted EPOCH-R in 4 children with certain B-cell cancers (DLBCL, PMBCL, or PTLD). The goal was to see if giving the drugs continuously over 4 days and adjusting doses based on blood cell counts is safe and effecti…

This study tested a new experimental therapy using special immune cells designed to attack five proteins found on pancreatic cancer cells. It included 37 patients whose cancer had returned, not gone away, or who could not have standard chemotherapy. The main goals were to check i…

This study looked at whether adding a cream made from human milk to the feedings of extremely premature babies (born weighing 500-1250 grams) helps them leave the hospital sooner. About 210 babies were split into two groups: one got the extra cream, the other got standard feeding…

This study tested whether trained peer mentors (ages 20-35) could help young adults (ages 17-25) with type 1 diabetes manage their blood sugar and successfully transition from pediatric to adult care. 144 participants were randomly assigned to receive peer support or standard car…

This study tested whether adding human milk cream to breast milk or donor milk could help very low birth weight preterm infants get enough calories to grow. Researchers measured the calorie content of the milk and added cream to bring it up to a standard level. The study included…

This study tested whether adding acupuncture to standard anti-nausea medication could better prevent nausea and vomiting after gallbladder removal surgery. 270 adults scheduled for laparoscopic cholecystectomy received either standard drugs alone or drugs plus acupuncture at spec…

This study looked at whether mailing self-test kits for HPV (the virus that can cause cervical cancer) could help more women get screened. It involved nearly 2,500 minority and underserved women who were overdue for screening. The goal was to see if a simple at-home test could ma…

This study looked at whether adding a sleep medication (lemborexant) to a standard alcohol craving medicine (naltrexone) helps reduce cravings and improve sleep in people with alcohol use disorder and insomnia. Eight adults from a treatment center took part. The goal was to see i…

This study tested a new program designed to help autistic children and teens manage anxiety in community settings. 32 participants aged 7-17 with autism and anxiety took part. The goal was to see if the program could be used effectively in local clinics to reduce anxiety symptoms…

This study tested whether a mobile app with guided imagery therapy could help children aged 7 to 12 with ongoing stomach pain. Four children used the app for 8 weeks, listening to 10-15 minute sessions most days. The goal was to see if the app could reduce pain frequency and inte…

This study tested if using a Fitbit activity tracker along with text message reminders could help Hispanic teenagers with obesity increase their physical activity and improve their sleep. 43 teens aged 14-16 took part. The goal was to see if this simple, technology-based approach…

This study looked at how donor human milk is given to very low birth weight infants in the NICU. The goal was to see if current feeding practices follow safety guidelines and properly monitor for electrolyte imbalances. 150 premature babies weighing 1250 grams or less were includ…

This early-phase trial tested whether adding the pneumonia drug atovaquone to standard chemotherapy is feasible for children and young adults with newly diagnosed acute myeloid leukemia (AML). The study enrolled 26 participants and focused on measuring drug levels in the blood an…

This study looked at 163 children aged 7-12 with chronic abdominal pain to see if simple tests (biomarkers) could predict whether they would benefit more from cognitive behavioral therapy (CBT) or a low FODMAP diet. The goal was to personalize treatment and improve symptom relief…

This study looked at a newer needle technique called fine needle biopsy (FNB) for diagnosing pancreatic masses. It involved 52 adults who needed a tissue sample from their pancreas. The goal was to see if FNB could provide better tissue samples and reduce the need for extra proce…

This study looked at whether giving very small premature babies (under 1000 grams at birth) a diet with extra protein helps them grow better and build more muscle. The babies received only human milk with added protein based on individual needs. The goal was to see if this approa…