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Engineered t cells take on blood cancers in early trial

NCT ID NCT00709033

First seen Feb 01, 2026 · Last updated May 25, 2026 · Updated 19 times

Summary

This early-phase study tested a new approach for people with advanced B-cell non-Hodgkin lymphoma or chronic lymphocytic leukemia (CLL) that had returned or not responded to standard treatments. Researchers took patients' own immune cells (T cells) and added a special receptor (anti-CD19) to help them recognize and attack cancer cells. The goal was to find a safe dose and see how long these modified cells lasted in the body. Only 3 patients took part, so results are very preliminary.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Houston Methodist Hospital

    Houston, Texas, 77030, United States

  • Texas Children's Hospital

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.